Smoking-Associated Carcinogen-Induced Inflammation Promotes Lung Carcinogenesis via IRAK4 Activation. Clinical Cancer Research. 2025; 31:746-755.
.A Single-Cell Transcriptome Atlas of Epithelial Subpopulations in HPV-Positive and HPV-Negative Head and Neck Cancers. Viruses-Basel. 2025; 17:461.
.Reducing clinical trial eligibility barriers for patients with MDS: an icMDS position statement. Blood. 2025; 145:1369-1381.
.Three-generation female cohort with macrocytic anemia and iron overload. American Journal of Hematology. 2025; 100:133-138.
.Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids. Cell Stem Cell. 2025; 32:824-837.e5.
.2025; 85:1596.
. Abstract 1596: Tumor-derived RAC1A159V gain-of-function mutation promotes an immunosuppressive tumor microenvironment and represses response to immune checkpoint inhibitors. Cancer Research.YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies. Cell. 2025; 188:331-351.e30.
.An engineered β-globin homology donor reveals insights into β-globin expression and betters HDR. Molecular Therapy. 2025; 33:1308-1309.
.2025; 31:s2-s3.
. Gene Therapy with Reduced-Intensity Conditioning for Sickle Cell Disease. Transplantation and Cellular Therapy.Dopaminergic encoding of future defensive actions in the mouse nucleus accumbens. Editor, Bahar I. PNAS Nexus. 2025; 4:pgaf128.
.Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia. Leukemia. 2025; 39:51-63.
.Examining the role of the photopigment melanopsin in the striatal dopamine response to light. Frontiers in Systems Neuroscience. 2025; 19:1568878.
.An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup. Science Translational Medicine. 2025; 17:eadr2012.
.GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis. Biochimica et Biophysica Acta (BBA): Molecular Basis of Disease. 2025; 1871:167565.
.IRAK1/4/pan-FLT3 Kinase Inhibitors with Reduced hERG Block as Treatments for Acute Myeloid Leukemia. ACS Medicinal Chemistry Letters. 2025; 16:887-895.
.Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution. Cell. 2025; 188:1623-1641.e26.
.Ubiquitin-conjugating enzyme UBE2N modulates proteostasis in immunoproteasome-positive acute myeloid leukemia. The Journal of Clinical Investigation. 2025; 135.
.Germline DDX41 mutations in myeloid neoplasms: the current clinical and molecular understanding. Current Opinion in Hematology. 2025; 32:67-76.
.Prevalence of cytopenia(s) and somatic variants in patients with DDX41 mutant germline predisposition syndrome. British Journal of Haematology. 2025; 206:1109-1120.
.SUV39H1 maintains cancer stem cell chromatin state and properties in glioblastoma. JCI insight. 2025; 10:e186344.
.Loss of Cpt1a results in elevated glucose-fueled mitochondrial oxidative phosphorylation and defective hematopoietic stem cells. The Journal of Clinical Investigation. 2025; 135:e184069.
.Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia. Blood Advances. 2025; 9:856-861.
.Structural Dynamics of Rho GTPases. Journal of Molecular Biology. 2025; 437:168919.
.The role of oligodendrocyte progenitor cells in the spatiotemporal vascularization of the human and mouse neocortex. Glia. 2025; 73:140-158.
.Tunneling nanotube-like structures regulate distant cellular interactions during heart formation. Science. 2025; 387:eadd3417.
.G-CSF resistance of ELANE-mutant neutropenia depends on SERF1-containing truncated-neutrophil elastase aggregates. The Journal of Clinical Investigation. 2025; 135:e177342.
.Unraveling lipid metabolism for acute myeloid leukemia therapy. Current Opinion in Hematology. 2025; 32:77-86.
.Granulocyte-Macrophage Colony Stimulating Factor Receptor Contributes to Plexiform Neurofibroma Initiation. Cancers. 2025; 17:905.
.2025; 29:104935.
. 137 Schwann Cell Glial Cell Line-Derived Neurotrophic Factor Signaling Influences Pain in Neurofibromatosis 1. Journal of Pain.Preclinical efficacy of a modified gamma-globin lentivirus gene therapy in Berkeley sickle cell anemia mice and human xenograft models. Molecular Therapy-Methods & Clinical Development. 2025; 33:101439.
.Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse brain defects. DMM Disease Models and Mechanisms. 2025; 18:dmm052110.
.Splicing regulatory dynamics for precision analysis and treatment of heterogeneous leukemias. Science Translational Medicine. 2025; 17:eadr1471.
.TIFAB modulates metabolic pathways in KMT2A::MLLT3-induced AML through HNF4A. Blood Advances. 2025; 9:844-855.
.Differential regulation of fetal bone marrow and liver hematopoiesis by yolk-sac-derived myeloid cells. Nature Communications. 2025; 16:4427.
.Intercellular mRNA transfer alters the human pluripotent stem cell state. Proceedings of the National Academy of Sciences of USA. 2025; 122:e2413351122.
.