Publications

Abe, H; Alavattam, KG; Hu, Y; Pang, Q; Andreassen, PR; Hegde, RS; Namekawa, SH. The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis. Current Biology. 2020; 30:408-420.e5.

Agrawal, M; Schwarz, P; Giaimo, BD; Bedzhov, I; Corbacioglu, A; Weber, D; Gaidzik, VI; Jahn, N; Ruecker, FG; Schroeder, T; et al. Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML). Leukemia. 2020; 34:630-634.

Alsaied, T; Niss, O; Tretter, JT; Powell, AW; Chin, C; Fleck, RJ; Cnota, JF; Malik, P; Quinn, CT; Nagueh, SM; et al. Left atrial dysfunction in sickle cell anemia is associated with diffuse myocardial fibrosis, increased right ventricular pressure and reduced exercise capacity. Scientific Reports. 2020; 10.

Althoff, MJ; Nayak, RC; Hegde, S; Wellendorf, AM; Bohan, B; Filippi, MD; Xin, M; Richard Lu, Q; Geiger, H; Zheng, Y; et al. Yap1-Scribble polarization is required for hematopoietic stem cell division and fate. Blood. 2020; 136:1824-1836.

Asleh, J; Shofty, B; Cohen, N; Kavushansky, A; Lopez-Juarez, A; Constantini, S; Ratner, N; Kahn, I. Brain-wide structural and functional disruption in mice with oligodendrocyte-specific Nf1 deletion is rescued by inhibition of nitric oxide synthase. Proceedings of the National Academy of Sciences of USA. 2020; 117:22506-22513.

Berry, K; Wang, J; Richard Lu, Q. Epigenetic regulation of oligodendrocyte myelination in developmental disorders and neurodegenerative diseases. F1000Research. 2020; 9:105-105.

Berry, KP; Lu, QR. Chromatin modification and epigenetic control in functional nerve regeneration. Seminars in Cell and Developmental Biology. 2020; 97:74-83.

Boucher, AA; Luchtman-Jones, L; Palumbo, JS; Cancelas, JA; Abu-El-Haija, M; Jenkins, TM; Lin, TK; Nathan, JD. Extreme Thrombocytosis after Pediatric Pancreatectomy with Islet Autotransplantation Is Unique Compared to Other Postsplenectomy States. Journal of Pediatric Surgery. 2020; 55:1645-1650.

Brown, A; Geiger, H. Role of cell cycle control, checkpoints, and DNA repair mechanisms in stem cells and changes with aging and cancerogenesis. Geriatric Oncology. : Springer International Publishing; Springer International Publishing; 2020.

Brown, A; Schuetz, D; Han, Y; Daria, D; Nattamai, KJ; Eiwen, K; Sakk, V; Pospiech, J; Saller, T; van Zant, G; et al. The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function. Haematologica: the hematology journal. 2020; 105:317-324.

Chaney, KE; Perrino, MR; Kershner, LJ; Patel, AV; Wu, J; Choi, K; Rizvi, TA; Dombi, E; Szabo, S; Largaespada, DA; et al. Cdkn2a Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST. Cancer Research. 2020; 80:4720-4730.

Crane, J; Manfredo, J; Boscolo, E; Coyan, M; Takemoto, C; Itkin, M; Adams, DM; Le Cras, TD. Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood angiopoietin-2 levels. Pediatric Blood and Cancer. 2020; 67.

D'Alessandro, A; Yoshida, T; Nestheide, S; Nemkov, T; Stocker, S; Stefanoni, D; Mohmoud, F; Rugg, N; Dunham, A; Cancelas, JA. Hypoxic storage of red blood cells improves metabolism and post-transfusion recovery. Transfusion. 2020; 60:786-798.

Fletcher, JS; Pundavela, J; Ratner, N. After Nf1 loss in Schwann cells, inflammation drives neurofibroma formation. 2020; 2:i23-i32.

Florian, MC; Leins, H; Gobs, M; Han, Y; Marka, G; Soller, K; Vollmer, A; Sakk, V; Nattamai, KJ; Rayes, A; et al. Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice. Aging Cell. 2020; 19.

Freedman, J; Tran, A; Tourdot, BE; Kalyanaraman, C; Perry, S; Holinstat, M; Jacobson, MP; Holman, TR. Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators. Biochemistry. 2020; 59:1832-1844.

Gasilina, A; Premnauth, G; Gurjar, P; Biesiada, J; Hegde, S; Milewski, D; Ma, G; Kalin, TV; Merino, E; Meller, J; et al. IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models. PLoS ONE. 2020; 15:e0229801-e0229801.

Golan, K; Singh, AK; Kollet, O; Bertagna, M; Althoff, MJ; Khatib-Massalha, E; Petrovich-Kopitman, E; Wellendorf, AM; Massalha, H; Levin-Zaidman, S; et al. Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma. Blood. 2020; 136:2607-2619.

Govindarajah, V; Lee, JM; Solomon, M; Goddard, B; Nayak, R; Nattamai, K; Geiger, H; Salomonis, N; Cancelas, JA; Reynaud, D. FOXO activity adaptation safeguards the hematopoietic stem cell compartment in hyperglycemia. Blood Advances. 2020; 4:5512-5526.

Gripp, KW; Schill, L; Schoyer, L; Stronach, B; Bennett, AM; Blaser, S; Brown, A; Burdine, R; Burkitt-Wright, E; Castel, P; et al. The sixth international RASopathies symposium: Precision medicine—From promise to practice. American Journal of Medical Genetics, Part A. 2020; 182:597-606.

Guo, J; Chaney, KE; Choi, K; Witek, G; Patel, AV; Xie, H; Lin, D; Whig, K; Xiong, Y; Schultz, DC; et al. Polo-like kinase 1 as a therapeutic target for malignant peripheral nerve sheath tumors (MPNST) and schwannomas. American Journal of Cancer Research. 2020; 10:856-869.

Heinrich, A; Potter, SJ; Guo, L; Ratner, N; DeFalco, T. Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis. Cell Reports. 2020; 31:107513-107513.

Hetzel, M; Lopez-Rodriguez, E; Mucci, A; Ha Nguyen, AH; Suzuki, T; Shima, K; Buchegger, T; Dettmer, S; Rodt, T; Bankstahl, JP; et al. Effective hematopoietic stem cell-based gene therapy in a murine model of hereditary pulmonary alveolar proteinosis. Haematologica: the hematology journal. 2020; 105:1147-1157.

Hinge, A; He, J; Bartram, J; Javier, J; Xu, J; Fjellman, E; Sesaki, H; Li, T; Yu, J; Wunderlich, M; et al. Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition. Cell Stem Cell. 2020; 26:420-430.e6.

Huang, Q; Lei, Y; Li, X; Guo, F; Liu, M. A Highlight of the Mechanisms of Immune Checkpoint Blocker Resistance. Frontiers in Cell and Developmental Biology. 2020; 8.

Jones, LM; Melgar, K; Bolanos, L; Hueneman, K; Walker, MM; Jiang, J; Wilson, KM; Zhang, X; Shen, J; Jiang, F; et al. Targeting AML-associated FLT3 mutations with a type I kinase inhibitor. Journal of Clinical Investigation. 2020; 130:2017-2023.

Kared, H; Tan, SW; Lau, MC; Chevrier, M; Tan, C; How, W; Wong, G; Strickland, M; Malleret, B; Amoah, A; et al. Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway. Nature Communications. 2020; 11.

Kelly, K; Cancelas, JA; Szczepiorkowski, ZM; Dumont, DF; Rugg, N; Dumont, LJ. Frozen Platelets—Development and Future Directions. Transfusion Medicine Reviews. 2020; 34:286-293.

Khandelwal, P; Chaturvedi, V; Owsley, E; Lane, A; Heyenbruch, D; Lutzko, CM; Leemhuis, T; Grimley, MS; Nelson, AS; Davies, SM; et al. CD38brightCD8+ T Cells Associated with the Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells. Biology of Blood and Marrow Transplantation. 2020; 26:1-6.

Khodoun, MV; Morris, SC; Angerman, E; Potter, C; Schuman, R; Wunderlich, M; Maciag, JJ; Locker, KC S; Mulloy, JC; Herr, AB; et al. Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies. Journal of Allergy and Clinical Immunology. 2020; 145:907-921.e3.

Laskin, BL; Denburg, MR; Furth, SL; Moatz, T; Altrich, M; Kleiboeker, S; Lutzko, C; Zhu, X; Blackard, JT; Jodele, S; et al. The Natural History of BK Polyomavirus and the Host Immune Response After Stem Cell Transplantation. Clinical Infectious Diseases. 2020; 71:3044-3054.

Le Cras, TD; Goines, J; Lakes, N; Pastura, P; Hammill, AM; Adams, DM; Boscolo, E. Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation. Angiogenesis. 2020; 23:425-442.

Li, Q; Li, L; Zhong, J; Huang, LF. Real-time sepsis severity prediction on knowledge graph deep learning networks for the intensive care unit. Journal of Visual Communication and Image Representation. 2020; 72:102901-102901.

Lin, Y; Wang, X; Rose, KP; Dai, M; Han, J; Xin, M; Pan, D. miR-143 Regulates Lysosomal Enzyme Transport across the Blood-Brain Barrier and Transforms CNS Treatment for Mucopolysaccharidosis Type I. Molecular Therapy. 2020; 28:2161-2176.

Lucas, D; Salomonis, N; Grimes, HL. Unraveling bone marrow architecture. Nature Cell Biology. 2020; 22:5-6.

Ma, Y; Gross, AM; Dombi, E; Pemov, A; Choi, K; Chaney, K; Rhodes, SD; Angus, SP; Sciaky, N; Clapp, DW; et al. A molecular basis for neurofibroma-associated skeletal manifestations in NF1. Genetics in Medicine. 2020; 22:1786-1793.

Motta, M; Pannone, L; Pantaleoni, F; Bocchinfuso, G; Radio, FC; Cecchetti, S; Ciolfi, A; Di Rocco, M; Elting, MW; Brilstra, EH; et al. Enhanced MAPK1 Function Causes a Neurodevelopmental Disorder within the RASopathy Clinical Spectrum. The American Journal of Human Genetics. 2020; 107:499-513.

Muench, DE; Olsson, A; Ferchen, K; Pham, G; Serafin, RA; Chutipongtanate, S; Dwivedi, P; Song, B; Hay, S; Chetal, K; et al. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature. 2020; 582:109-114.

Munir, S; Basu, A; Maity, P; Krug, L; Haas, P; Jiang, D; Strauss, G; Wlaschek, M; Geiger, H; Singh, K; et al. TLR4-dependent shaping of the wound site by MSCs accelerates wound healing. EMBO Reports. 2020; 21.

Muraleedharan, R; Gawali, MV; Tiwari, D; Sukumaran, A; Oatman, N; Anderson, J; Nardini, D; Bhuiyan, MA N; Tkac, I; Ward, AL; et al. AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival. Cell Reports. 2020; 32:108092-108092.

Muto, T; Walker, CS; Choi, K; Hueneman, K; Smith, MA; Gul, Z; Garcia-Manero, G; Ma, A; Zheng, Y; Starczynowski, DT. Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs. Nature Immunology. 2020; 21:535-545.

Na, Y; Huang, G; Wu, J. The Role of RUNX1 in NF1-Related Tumors and Blood Disorders. Molecules and Cells. 2020; 43:153-159.

Nalapareddy, K; Geiger, H. Analysis of Aged Dysfunctional Intestinal Stem Cells. Methods in molecular biology (Clifton, N.J.). 2020; 2171:41-52.

Nelson, AS; Heyenbruch, D; Rubinstein, JD; Sabulski, A; Jodele, S; Thomas, S; Lutzko, C; Zhu, X; Leemhuis, T; Cancelas, JA; et al. Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients. Blood Advances. 2020; 4:5745-5754.

Nie, Y; Wilson, AF; DeFalco, T; Meetei, AR; Namekawa, SH; Pang, Q. FANCD2 is required for the repression of germline transposable elements. Reproduction. 2020; 159:659-668.

Niederkorn, M; Agarwal, P; Starczynowski, DT. TIFA and TIFAB: FHA-domain proteins involved in inflammation, hematopoiesis, and disease. Experimental Hematology. 2020; 90:18-29.

Niederkorn, M; Hueneman, K; Choi, K; Varney, ME; Romano, L; Pujato, MA; Greis, KD; Inoue, J; Meetei, R; Starczynowski, DT. TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. Cell Reports. 2020; 30:2776-2790.e6.

Niss, O; Lane, A; Asnani, MR; Yee, ME; Raj, A; Creary, S; Fitzhugh, C; Bodas, P; Saraf, SL; Sarnaik, S; et al. Progression of albuminuria in patients with sickle cell anemia: A multicenter, longitudinal study. Blood Advances. 2020; 4:1501-1511.

Palomo-Irigoyen, M; Pérez-Andrés, E; Iruarrizaga-Lejarreta, M; Barreira-Manrique, A; Tamayo-Caro, M; Vila-Vecilla, L; Moreno-Cugnon, L; Beitia, N; Medrano, D; Fernández-Ramos, D; et al. HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis. Journal of Clinical Investigation. 2020; 130:3848-3864.

Parras, C; Marie, C; Zhao, C; Lu, QR. Chromatin remodelers in oligodendroglia. Glia. 2020; 68:1604-1618.

Patel, SK; Hartley, RM; Wei, X; Furnish, R; Escobar-Riquelme, F; Bear, H; Choi, K; Fuller, C; Phoenix, TN. Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation. Neuro-Oncology. 2020; 22:381-392.

Perry, SC; Horn, T; Tourdot, BE; Yamaguchi, A; Kalyanaraman, C; Conrad, WS; Akinkugbe, O; Holinstat, M; Jacobson, MP; Holman, TR. Role of human 15-lipoxygenase-2 in the biosynthesis of the lipoxin intermediate, 5S,15S-Dihpete, implicated with the altered positional specificity of human 15-lipoxygenase-1. Biochemistry. 2020; 59:4118-4130.

Perry, SC; Kalyanaraman, C; Tourdot, BE; Conrad, WS; Akinkugbe, O; Freedman, JC; Holinstat, M; Jacobson, MP; Holman, TR. 15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-Lipoxygenase-2 in biosynthesis of resolvin D5. Journal of lipid research. 2020; 61:1087-1103.

Rodriguez, S; Abundis, C; Boccalatte, F; Mehrotra, P; Chiang, MY; Yui, MA; Wang, L; Zhang, H; Zollman, A; Bonfim-Silva, R; et al. Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL. Leukemia. 2020; 34:1241-1252.

Rodriguez-Romaguera, J; Ung, RL; Nomura, H; Otis, JM; Basiri, ML; Namboodiri, VM K; Zhu, X; Robinson, JE; van den Munkhof, HE; McHenry, JA; et al. Prepronociceptin-Expressing Neurons in the Extended Amygdala Encode and Promote Rapid Arousal Responses to Motivationally Salient Stimuli. Cell Reports. 2020; 33:108362-108362.

Rubinstein, JD; Burns, K; Absalon, M; Lutzko, C; Leemhuis, T; Chandra, S; Hanley, PJ; Keller, MD; Davies, SM; Nelson, A; et al. EBV-directed viral-specific T-lymphocyte therapy for the treatment of EBV-driven lymphoma in two patients with primary immunodeficiency and DNA repair defects. Pediatric Blood and Cancer. 2020; 67.

Rubinstein, JD; Zhu, X; Lutzko, C; Leemhuis, T; Cancelas, JA; Jodele, S; Bollard, CM; Hanley, PJ; Davies, SM; Grimley, MS; et al. Complement inhibition does not impair the clinical antiviral capabilities of virus-specific T-cell therapy. Blood Advances. 2020; 4:3252-3257.

Schieber, M; Marinaccio, C; Bolanos, LC; Haffey, WD; Greis, KD; Starczynowski, DT; Crispino, JD. FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome. Blood Cancer Journal. 2020; 10.

Schrenk, S; Goines, J; Boscolo, E. A patient-derived xenograft model for venous malformation. Jove-Journal of Visualized Experiments. 2020; 2020:1-14.

Seu, KG; Trump, LR; Emberesh, S; Lorsbach, RB; Johnson, C; Meznarich, J; Underhill, HR; Chou, ST; Sakthivel, H; Nassar, NN; et al. VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. The American Journal of Human Genetics. 2020; 107:1149-1156.

Siems, SB; Jahn, O; Eichel, MA; Kannaiyan, N; Wu, LM N; Sherman, DL; Kusch, K; Hesse, D; Jung, RB; Fledrich, R; et al. Proteome profile of peripheral myelin in healthy mice and in a neuropathy model. eLife. 2020; 9.

Singh, AK; Cancelas, JA. Gap junctions in the bone marrow lympho-hematopoietic stem cell niche, leukemia progression, and chemoresistance. International Journal of Molecular Sciences. 2020; 21:796-796.

Singh, RN; Seo, J; Singh, NN. RNA in spinal muscular atrophy: therapeutic implications of targeting. Expert Opinion on Therapeutic Targets. 2020; 24:731-743.

Smith, MA; Culver-Cochran, AE; Adelman, ER; Rhyasen, GW; Ma, A; Figueroa, ME; Starczynowski, DT. TNFAIP3 Plays a Role in Aging of the Hematopoietic System. Frontiers in Immunology. 2020; 11.

Solomon, M; DeLay, M; Reynaud, D. Phenotypic Analysis of the Mouse Hematopoietic Hierarchy Using Spectral Cytometry: From Stem Cell Subsets to Early Progenitor Compartments. Cytometry Part B: Clinical Cytometry. 2020; 97:1057-1065.

Starczynowski, DT. HHEX expression drives AML development. Blood. 2020; 136:1575-1576.

Su, R; Dong, L; Li, Y; Gao, M; Han, L; Wunderlich, M; Deng, X; Li, H; Huang, Y; Gao, L; et al. Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion. Cancer Cell. 2020; 38:79-96.e11.

Tackenberg, H; Moeller, S; Filippi, M; Laskay, T. The Small GTPase Cdc42 Is a Major Regulator of Neutrophil Effector Functions. Frontiers in Immunology. 2020; 11.

Ueno, M; Nakamura, Y; Nakagawa, H; Niehaus, JK; Maezawa, M; Gu, Z; Kumanogoh, A; Takebayashi, H; Lu, QR; Takada, M; et al. Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction after Spinal Cord Injury. Cerebral Cortex. 2020; 30:5702-5716.

Wang, J; He, X; Meng, H; Li, Y; Dmitriev, P; Tian, F; Page, JC; Lu, QR; He, Z. Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia. Neuron. 2020; 108:876-886.e4.

Wang, J; Lu, QR. Convergent epigenetic regulation of glial plasticity in myelin repair and brain tumorigenesis: A focus on histone modifying enzymes. Neurobiology of Disease. 2020; 144:105040-105040.

Wang, J; Wang, J; Yang, L; Zhao, C; Wu, LN; Xu, L; Zhang, F; Weng, Q; Wegner, M; Lu, QR. CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair. Nature Communications. 2020; 11.

Wang, J; Yang, L; Dong, C; Wang, J; Xu, L; Qiu, Y; Weng, Q; Zhao, C; Xin, M; Lu, QR. EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP, and senescence pathways. Science Advances. 2020; 6:eaaz6477-eaaz6477.

Weng, Q; Zhao, M; Zheng, J; Yang, L; Xu, Z; Zhang, Z; Wang, J; Wang, J; Yang, B; Lu, QR; et al. STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia. Cell Death and Differentiation. 2020; 27:130-145.

Xie, Y; Gao, L; Xu, C; Chu, L; Gao, L; Wu, R; Liu, Y; Liu, T; Sun, X; Ren, R; et al. ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients. Haematologica: the hematology journal. 2020; 105:925-936.

Xu, J; Jahromi, AK; Brake, J; Robinson, JE; Yang, C. Interferometric speckle visibility spectroscopy (ISVS) for human cerebral blood flow monitoring. APL Photonics. 2020; 5:126102-126102.

Yazer, MH; Spinella, PC; Doyle, L; Kaufman, RM; Dunn, R; Hess, JR; Filho, LA; Fontaine, M; Gathof, B; Jackson, B; et al. Transfusion of uncrossmatched group o erythrocyte-containing products does not interfere with most ABO typings. Anesthesiology. 2020; 132:525-534.

Yokota, A; Huo, L; Lan, F; Wu, J; Huang, G. The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies. Molecules and Cells. 2020; 43:145-152.

Yu, Y; Choi, K; Wu, J; Andreassen, PR; Dexheimer, PJ; Keddache, M; Brems, H; Spinner, RJ; Cancelas, JA; Martin, LJ; et al. NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation. Acta Neuropathologica. 2020; 139:157-174.

Zeng, X; Zhu, S; Hou, Y; Zhang, P; Li, L; Li, J; Huang, LF; Lewis, SJ; Nussinov, R; Cheng, F. Network-based prediction of drug-target interactions using an arbitrary-order proximity embedded deep forest. Bioinformatics. 2020; 36:2805-2812.

Zhang, C; Fondufe-Mittendorf, YN; Wang, C; Chen, J; Cheng, Q; Zhou, D; Zheng, Y; Geiger, H; Liang, Y. Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance. Haematologica: the hematology journal. 2020; 105:573-584.

Zhang, H; Qi, L; Du, Y; Huang, LF; Braun, FK; Kogiso, M; Zhao, Y; Li, C; Lindsay, H; Zhao, S; et al. Patient-derived orthotopic xenograft (PDOX) mouse models of primary and recurrent meningioma. Cancers. 2020; 12:1478-17.