2024; 84:1464.
. Abstract 1464: Smoking carcinogen-induced inflammation promotes lung carcinogenesis via IRAK4 activation. Cancer Research.ATF7IP2/MCAF2 directs H3K9 methylation and meiotic gene regulation in the male germline. Genes and Development. 2024; 38:115-130.
.A toxicology study of Csf2ra complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice. Molecular Therapy-Methods & Clinical Development. 2024; 32:101213.
.2024; 84:3092.
. Abstract 3092: MICRO-TAG: A novel fluorescence-based real-time cellular target engagement platform for drug discovery. Cancer Research.Neural responses to decision-making in suicide attempters with youth major depressive disorder. NeuroImage-Clinical. 2024; 43:103667.
.Dysregulated innate immune signaling cooperates with RUNX1 mutations to transform an MDS-like disease to AML. iScience. 2024; 27:109809.
.Adult microglial TGFβ1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in mice. Nature Communications. 2024; 15:5306.
.Immortalised chronic myeloid leukemia (CML) derived mesenchymal stromal cells (MSCs) line retains the immunomodulatory and chemoprotective properties of CML patient-derived MSCs. Cellular Signalling. 2024; 116:111067.
.Soluble glycoprotein VI predicts abdominal aortic aneurysm growth rate and is a novel therapeutic target. Blood. 2024; 144:1663-1678.
.In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy. Cancer Cell. 2024; 42:1955-1969.e7.
.SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation. Cell Reports. 2024; 43:114536.
.2024; 135:awe146.
. Abstract We146: CHD8 is Essential for Postnatal Heart Function through Preserving Mitochondrial Integrity. Circulation Research.Zinc-Finger Protein ZFP488 Regulates the Timing of Oligodendrocyte Myelination and Remyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024; 44:e0141242024.
.Chemotherapy resistance in acute myeloid leukemia is mediated by A20 suppression of spontaneous necroptosis. Nature Communications. 2024; 15:9189.
.Macrophage memories of early-life injury drive neonatal nociceptive priming. Cell Reports. 2024; 43:114129.
.The mediating role of family functioning between childhood trauma and depression severity in major depressive disorder and bipolar disorder. Journal of Affective Disorders. 2024; 365:443-450.
.2024; 3:1339870.
. Research and clinical updates on IRAK4 and its roles in inflammation and malignancy: themes and highlights from the 1st symposium on IRAK4 in cancer.Gestational diabetes in mice induces hematopoietic memory that affects the long-term health of the offspring. The Journal of Clinical Investigation. 2024; 134:e169730.
.Capillary malformations. The Journal of Clinical Investigation. 2024; 134:e172842.
.Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets. Blood. 2024; 144:1732-1746.
.DOR activation in mature oligodendrocytes regulates α-ketoglutarate metabolism leading to enhanced remyelination in aged mice. Nature Neuroscience. 2024; 27:2073-2085.
.Shared patterns of glial transcriptional dysregulation link Huntington's disease and schizophrenia. Brain: a journal of neurology. 2024; 147:3099-3112.
.2024; 26:e20-e21.
. CMV SEROSTATUS IS MOST IMPORTANT TO SELECT DONORS OF MONONUCLEAR CELL PRODUCTS AIMED TO THE GENERATION OF ANTI-CMV VIRUS-SPECIFIC T CELL (VSTS) PRODUCTS. Cytotherapy (Informa).Inhibition of NRF2 signaling overcomes acquired resistance to arsenic trioxide in FLT3-mutated Acute Myeloid Leukemia. Annals of Hematology. 2024; 103:1919-1929.
.Third-party virus-specific T cells for the treatment of double-stranded DNA viral reactivation and posttransplant lymphoproliferative disease after solid organ transplant. American Journal of Transplantation. 2024; 24:1634-1643.
.Biomolecular condensates: hubs of Hippo-YAP/TAZ signaling in cancer. Trends in Cell Biology. 2024; 34:566-577.
.Red cell abnormalities characterized by ektacytometry in children with cholestasis. Pediatric Research. 2024; 95:1035-1040.
.A road map for the treatment of pediatric diffuse midline glioma. Cancer Cell. 2024; 42:1-5.
.Absence of PNH-clones in DDX41mutant-GPS aids in their distinction from acquired BM failure syndromes. Leukemia Research: clinical and laboratory studies. 2024; 145:107561.
.In vivo ablation of NF-κB cascade effectors alleviates disease burden in myeloproliferative neoplasms. Blood. 2024; 143:2414-2424.
.Tumor-derived RHOA mutants interact with effectors in the GDP-bound state. Nature Communications. 2024; 15:7176.
.Intrinsic link between PGRN and Gba1 D409V mutation dosage in potentiating Gaucher disease. Human Molecular Genetics. 2024; 33:1771-1788.
.Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration. Cell. 2024; 187:2465-2484.e22.
.Methodological issues in the evaluation of cold snare endoscopic mucosal resection for colon polyps. Endoscopy. 2024; 56:79.
.Metabolic reprogramming regulated by TRAF6 contributes to the leukemia progression. Leukemia. 2024; 38:1032-1045.
.CRISPR/Cas9 deletion of MIR155HG in human T cells reduces incidence and severity of acute GVHD in a xenogeneic model. Blood Advances. 2024; 8:947-958.
.A Multimodal Drug-Diet-Immunotherapy Combination Restrains Melanoma Progression and Metastasis. Cancer Research. 2024; 84:2333-2351.
.A super minigene with a short promoter and truncated introns recapitulates essential features of transcription and splicing regulation of the SMN1 and SMN2 genes. Nucleic Acids Research (NAR). 2024; 52:3547-3571.
.U1 snRNA interactions with deep intronic sequences regulate splicing of multiple exons of spinal muscular atrophy genes. Frontiers in Neuroscience. 2024; 18:1412893.
.Treosulfan Exposure Predicts Thalassemia-Free Survival in Patients with Beta Thalassemia Major Undergoing Allogeneic Hematopoietic Cell Transplantation. Clinical Pharmacology and Therapeutics. 2024; 115:116-125.
.NRASQ61R mutation drives elevated angiopoietin-2 expression in human endothelial cells and a genetic mouse model. Pediatric Blood and Cancer. 2024; 71:e31032.
.NF1-dependent disruption of the blood-nerve-barrier is improved by blockade of P2RY14. iScience. 2024; 27:110294.
.Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors. Frontiers in Immunology. 2024; 15:1384623.
.C5aR plus MEK inhibition durably targets the tumor milieu and reveals tumor cell phagocytosis. Life Science Alliance. 2024; 7:e202302229.
.Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance. Science Advances. 2024; 10:eado6342.
.The Effects of Variation in the GABAA Receptor Gene on Anxious Depression are Mediated by the Functional Connectivity Between the Amygdala and Middle Frontal Gyrus. Neuropsychiatric Disease and Treatment. 2024; 20:1781-1796.
.Schwann cells modulate nociception in neurofibromatosis 1. JCI insight. 2024; 9:e171275.
.GM-CSF brings (good) memories. Blood. 2024; 143:2683-2684.
.ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms. Haematologica: the hematology journal. 2024; 109:1426-1438.
.Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models. Science Translational Medicine. 2024; 16:eadn1285.
.Single-cell sequencing dissects the transcriptional identity of activated fibroblasts and identifies novel persistent distal tubular injury patterns in kidney fibrosis. Scientific Reports. 2024; 14:439.
.The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation. Glia. 2024; 72:1304-1318.
.Protocol for three-dimensional whole-mount imaging of the vascular network in the intestinal muscle. Star Protocols. 2024; 5:103170.
.Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia. 2024; 38:1501-1510.
.Preclinical safety assessment of modified gamma globin lentiviral vector-mediated autologous hematopoietic stem cell gene therapy for hemoglobinopathies. Editor, Ling C. PloS one. 2024; 19:e0306719.
.Targeting Acute Myeloid Leukemia Stem Cells through Perturbation of Mitochondrial Calcium. Cancer Discovery. 2024; 14:1922-1939.
.Slow cycling and durable Flt3+ progenitors contribute to hematopoiesis under native conditions. The Journal of Experimental Medicine. 2024; 221:e20231035.
.DDX41 haploinsufficiency causes inefficient hematopoiesis under stress and cooperates with p53 mutations to cause hematologic malignancy. Leukemia. 2024; 38:1787-1798.
.Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia. Nature Genetics. 2024; 56:2434-2446.
.Electrophysiological predictors of early response to antidepressants in major depressive disorder. Journal of Affective Disorders. 2024; 365:509-517.
.Accelerating drug discovery and repurposing by combining transcriptional signature connectivity with docking. Science Advances. 2024; 10:eadj3010.
.In vitro quality parameters of whole blood-derived platelets pooled using two different platelet pooling sets and stored up to 7 days are similar. Transfusion. 2024; 64:132-140.
.CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells. Cancer Discovery. 2024; 14:1860-1878.
.BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination. The Journal of Cell Biology. 2024; 223:e202310143.
.Single cell RNA-seq reveals cellular and transcriptional heterogeneity in the splenic CD11b+Ly6Chigh monocyte population expanded in sepsis-surviving mice. Molecular medicine (Cambridge, Mass.). 2024; 30:202.
.Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature. 2024; 627:839-846.
.Chaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201. Neuro-Oncology. 2024; 26:735-748.
.Sensors and Devices Guided by Artificial Intelligence for Personalized Pain Medicine. Cyborg and Bionic Systems. 2024; 5:0160.
.Efficacy and advantage of immunotherapy for melanoma via intramuscular co-expression of plasmid-encoded PD-1 and CTLA-4 scFvs. AMERICAN JOURNAL OF CANCER RESEARCH. 2024; 14:2626-2642.
.Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia. Genes and Diseases. 2024; 11:413-429.
.Aberrant high-beta band functional connectivity during reward processing in melancholic major depressive disorder: An MEG study. NeuroImage-Clinical. 2024; 43:103666.
.2024; 150:a4118360.
. Abstract 4118360: Lipocalin10 is Critical for Macrophage Efferocytosis to Repair Myocardial Ischemia/Reperfusion Injury. Circulation.Conditioning for alloengraftment in FA. Blood. 2024; 143:2120-2122.
.