Experimental Hematology and Cancer Biology
Meet the Team

Meet the Experimental Hematology and Cancer Biology Team

Director

Yi Zheng, PhD

Professor, UC Department of Pediatrics

Research Interests

Using transgenic and gene targeted mouse models to study the physiological and pathological roles of Rho GTPases and their regulators in...

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Faculty

Paul R. Andreassen, PhD

Professor, UC Department of Pediatrics

Email paul.andreassen@cchmc.org

Research Interests

Fanconi anemia; breast cancer susceptibility; genetic variants; genome instability; DNA damage responses; replication stress; relationship of DNA...

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Mohammad Azam, PhD

Professor, UC Department of Pediatrics

Email mohammad.azam@cchmc.org

Research Interests

Structure and function analysis of tyrosine kinases involved in the pathogenesis of leukemia; molecular basis of "oncogene addiction" modeling of...

Elisa Boscolo, PhD

Associate Professor, UC Department of Pediatrics

Email elisa.boscolo@cchmc.org

Research Interests

Vascular anomalies; endothelial cell biology; mTOR signaling.

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Timothy M. Chlon, PhD

Assistant Professor, UC Department of Pediatrics

Email timothy.chlon@cchmc.org

Research Interests

Inherited susceptibility to myelodysplastic syndrome, myeloid leukemia, and bone marrow failure; ribosome biogenesis and snoRNA processing

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Marie-Dominique Filippi, PhD

Professor, UC Department of Pediatrics

Email marie-dominique.filippi@cchmc.org

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H. Leighton "Lee" Grimes, PhD

Professor, UC Department of Pediatrics

Email lee.grimes@cchmc.org

Research Interests

Acute myelogenous leukemia; T-cell acute lymphoblastic leukemia; severe congenital neutropenia; hematopoiesis; myelopoiesis; lineage decision;...

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Fukun Guo, PhD

Professor, UC Department of Pediatrics

Email fukun.guo@cchmc.org

Research Interests

Rho GTPases and T and B lymphocyte development and function

Courtney L. Jones, PhD

Assistant Professor, UC Department of Pediatrics

Email courtney.jones@cchmc.org

Research Interests

Acute myeloid leukemia; leukemia stem cells; cancer metabolism

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Theodosia A. Kalfa, MD, PhD

Professor, UC Department of Pediatrics

Email theodosia.kalfa@cchmc.org

Research Interests

Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species

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Jennifer Kamens, MD

Assistant Professor, UC Department of Pediatrics

Email Jennifer.Kamens@cchmc.org

Research Interests

Translational research in high risk leukemias with a specific focus on understanding DNA damage repair mechanisms in pediatric AML and the use of...

Ashish R. Kumar, MD, PhD

Professor, UC Department of Pediatrics

Email ashish.kumar@cchmc.org

Research Interests

Leukemia biology; cancer biology

Adam Lane, PhD

Assistant Professor, UC Department of Pediatrics

Email adam.lane@cchmc.org

Research Interests

Clinical trials; survival analysis; structural equation modeling

Qing Richard Lu, PhD

Professor, UC Department of Pediatrics

Email richard.lu@cchmc.org

Research Interests

Neoplastic stem cells; malignant glioma; pediatric brain tumors such as medulloblastoma, ependymoma, and diffuse midline gliomas (DMG / DIPG); tumor...

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Linde A. Miles, PhD

Assistant Professor, UC Department of Pediatrics

Email linde.miles@cchmc.org

Research Interests

Acute myeloid leukemia; cancer biology; cancer evolution; single cell multi-omic technologies

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Benjamin E. Mizukawa, MD

Associate Professor, UC Department of Pediatrics

Email benjamin.mizukawa@cchmc.org

Nicolas Nassar, PhD

Associate Professor, UC Department of Pediatrics

Email nicolas.nassar@cchmc.org

Dao Pan, PhD

Professor, UC Department of Pediatrics

Email dao.pan@cchmc.org

Research Interests

Viral vector-mediated gene therapy; stem cell therapy; neurological lysosomal storage diseases; neuroinflammation, BBB remodeling and immunotherapy...

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