Our lab (EpiFluidLab) is an epigenomics and computational biology lab within the Division of Human Genetics, Department of Pediatrics in the Cincinnati Children’s Hospital Medical Center and also part of the College of Medicine, University of Cincinnati.

Major Research Areas

  • Computational Biology
  • Epigenomics and Genomics
  • Liquid Biopsy
  • Precision Medicine 

We develop and apply machine learning and high throughput experimental methods (especially next-generation sequencing) to understand the gene regulatory circuits behind non-coding genetic variants. Specifically, we strive to extract genetic and multi-dimensional epigenetic information from circulating cell-free DNA, exosomes and their related cell types to explore the role of epigenetics in gene regulation. This may bridge the gap between genetic and phenotypic variations in different healthy and pathological conditions.  

For additional information, please visit Dr. Liu’s resource website.