Perl Lab

Perl Lab

Du, Y; Guo, M; Wu, Y; Wagner, A; Perl, AK; Wikenheiser-Brokamp, K; Yu, J; Gupta, N; Kopras, E; Krymskaya, V; et al. Lymphangioleiomyomatosis (LAM) Cell Atlas. Thorax. 2023; 78:85-87.

Riccetti, MR; Ushakumary, MG; Waltamath, M; Green, J; Snowball, J; Dautel, SE; Endale, M; Lami, B; Woods, J; Ahlfeld, SK; et al. Maladaptive functional changes in alveolar fibroblasts due to perinatal hyperoxia impair epithelial differentiation. JCI insight. 2022; 7:e152404.

Teitz-Tennenbaum, S; Viglianti, SP; Jomma, A; Palone, Q; Andrews, H; Selbmann, KN; Lahiri, S; Subbotina, N; Walker, N; Perl, AK T; et al. Sustained Club Cell Injury in Mice Induces Histopathologic Features of Deployment-Related Constrictive Bronchiolitis. The American journal of pathology. 2022; 192:410-425.

Sun, X; Perl, AK; Li, R; Bell, SM; Sajti, E; Kalinichenko, VV; Kalin, TV; Misra, RS; Deshmukh, H; Clair, G; et al. A census of the lung: CellCards from LungMAP. Developmental Cell. 2022; 57:112-145.e2.

Tisdale-Macioce, N; Green, J; Perl, AK T; Ashbaugh, A; Wiederhold, NP; Patterson, TF; Cushion, MT. The Promise of Lung Organoids for Growth and Investigation of Pneumocystis Species. Frontiers in Fungal Biology. 2021; 2:740845.

Sitaraman, S; Martin, EP; Na, CL; Zhao, S; Green, J; Deshmukh, H; Perl, AK T; Bridges, JP; Xu, Y; Weaver, TE. Surfactant protein C mutation links postnatal type 2 cell dysfunction to adult disease. JCI insight. 2021; 6:e142501.

Ushakumary, MG; Riccetti, M; Perl, AK T. Resident interstitial lung fibroblasts and their role in alveolar stem cell niche development, homeostasis, injury, and regeneration. Stem cells translational medicine. 2021; 10:1021-1032.

Gokey, JJ; Snowball, J; Green, J; Waltamath, M; Spinney, JJ; Black, KE; Hariri, LP; Xu, Y; Perl, AK. Pretreatment of aged mice with retinoic acid supports alveolar regeneration via upregulation of reciprocal PDGFA signalling. Thorax. 2021; 76:456-467.

Guo, M; Yu, JJ; Perl, AK; Wikenheiser-Brokamp, KA; Riccetti, M; Zhang, EY; Sudha, P; Adam, M; Potter, A; Kopras, EJ; et al. Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. American Journal of Respiratory and Critical Care Medicine. 2020; 202:1373-1387.

Riccetti, M; Gokey, JJ; Aronow, B; Perl, AT. The elephant in the lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration. Matrix Biology. 2020; 91-92:51-74.

Guo, M; Du, Y; Gokey, JJ; Ray, S; Bell, SM; Adam, M; Sudha, P; Perl, AK; Deshmukh, H; Potter, SS; et al. Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nature Communications. 2019; 10:37.

Liu, Z; Liao, F; Scozzi, D; Furuya, Y; Pugh, KN; Hachem, R; Chen, DL; Cano, M; Green, JM; Krupnick, AS; et al. An obligatory role for club cells in preventing obliterative bronchiolitis in lung transplants. JCI insight. 2019; 5:124732.