Perl Lab

Ushakumary, MG; Riccetti, M; Perl, AK T. Resident interstitial lung fibroblasts and their role in alveolar stem cell niche development, homeostasis, injury, and regeneration. Stem cells translational medicine. 2021; 10:1021-1032.

Gokey, JJ; Snowball, J; Green, J; Waltamath, M; Spinney, JJ; Black, KE; Hariri, LP; Xu, Y; Perl, AK. Pretreatment of aged mice with retinoic acid supports alveolar regeneration via upregulation of reciprocal PDGFA signalling. Thorax. 2021; 76:456-467.

Guo, M; Yu, JJ; Perl, AK; Wikenheiser-Brokamp, KA; Riccetti, M; Zhang, EY; Sudha, P; Adam, M; Potter, A; Kopras, EJ; et al. Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. American Journal of Respiratory and Critical Care Medicine. 2020; 202:1373-1387.

Riccetti, M; Gokey, JJ; Aronow, B; Perl, AT. The elephant in the lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration. Matrix Biology. 2020; 91-92:51-74.

Guo, M; Du, Y; Gokey, JJ; Ray, S; Bell, SM; Adam, M; Sudha, P; Perl, AK; Deshmukh, H; Potter, SS; et al. Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nature Communications. 2019; 10.

Liu, Z; Liao, F; Scozzi, D; Furuya, Y; Pugh, KN; Hachem, R; Chen, DL; Cano, M; Green, JM; Krupnick, AS; et al. An obligatory role for club cells in preventing obliterative bronchiolitis in lung transplants. JCI insight. 2019; 5.

Gokey, JJ; Snowball, J; Sridharan, A; Speth, JP; Black, KE; Hariri, LP; Perl, AT; Xu, Y; Whitsett, JA. MEG3 is increased in idiopathic pulmonary fibrosis and regulates epithelial cell differentiation. JCI insight. 2018; 3.

Gokey, JJ; Sridharan, A; Xu, Y; Green, J; Carraro, G; Stripp, BR; Perl, AT; Whitsett, JA. Active epithelial Hippo signaling in idiopathic pulmonary fibrosis. JCI insight. 2018; 3.

Ardini-Poleske, ME; Clark, RF; Ansong, C; Carson, JP; Corley, RA; Deutsch, GH; Hagood, JS; Kaminski, N; Mariani, TJ; Potter, SS; et al. LungMAP: The Molecular Atlas of Lung Development Program. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2017; 313:L733-L740.

Ahlfeld, SK; Perl, AK. A "GLI-tch " in Alveolar Myofibroblast Differentiation. American Journal of Respiratory Cell and Molecular Biology. 2017; 57:261-262.

Endale, M; Ahlfeld, S; Bao, E; Chen, X; Green, J; Bess, Z; Weirauch, M; Xu, Y; Perl, AK. Dataset on transcriptional profiles and the developmental characteristics of PDGFRα expressing lung fibroblasts. Data in Brief. 2017; 13:415-431.

Endale, M; Ahlfeld, S; Bao, E; Chen, X; Green, J; Bess, Z; Weirauch, MT; Xu, Y; Perl, AK. Temporal, spatial, and phenotypical changes of PDGFRα expressing fibroblasts during late lung development. Developmental Biology. 2017; 425:161-175.

Du, Y; Kitzmiller, JA; Sridharan, A; Perl, AK; Bridges, JP; Misra, RS; Pryhuber, GS; Mariani, TJ; Bhattacharya, S; Guo, M; et al. Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development. Thorax. 2017; 72:481-484.

Cox, AM; Gao, Y; Perl, AT; Tepper, RS; Ahlfeld, SK. Cumulative effects of neonatal hyperoxia on murine alveolar structure and function. Pediatric Pulmonology. 2017; 52:616-624.