Perl Lab

Guo, M; Yu, JJ; Perl, AK; Wikenheiser-Brokamp, KA; Riccetti, M; Zhang, EY; Sudha, P; Adam, M; Potter, A; Kopras, EJ; et al. Single-cell transcriptomic analysis identifies a unique pulmonary lymphangioleiomyomatosis cell. American Journal of Respiratory and Critical Care Medicine. 2020; 202:1373-1387.

Riccetti, M; Gokey, JJ; Aronow, B; Perl, AT. The elephant in the lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration. Matrix Biology. 2020; 91-92:51-74.

Liu, Z; Liao, F; Scozzi, D; Furuya, Y; Pugh, KN; Hachem, R; Chen, DL; Cano, M; Green, JM; Krupnick, AS; et al. An obligatory role for club cells in preventing obliterative bronchiolitis in lung transplants. JCI insight. 2019; 5.

Guo, M; Du, Y; Gokey, JJ; Ray, S; Bell, SM; Adam, M; Sudha, P; Perl, AK; Deshmukh, H; Potter, SS; et al. Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nature Communications. 2019; 10:37-37.

Gokey, JJ; Snowball, J; Sridharan, A; Speth, JP; Black, KE; Hariri, LP; Perl, AT; Xu, Y; Whitsett, JA. MEG3 is increased in idiopathic pulmonary fibrosis and regulates epithelial cell differentiation. JCI insight. 2018; 3.

Gokey, JJ; Sridharan, A; Xu, Y; Green, J; Carraro, G; Stripp, BR; Perl, AT; Whitsett, JA. Active epithelial Hippo signaling in idiopathic pulmonary fibrosis. JCI insight. 2018; 3.

Ardini-Poleske, ME; Clark, RF; Ansong, C; Carson, JP; Corley, RA; Deutsch, GH; Hagood, JS; Kaminski, N; Mariani, TJ; Potter, SS; et al. LungMAP: The Molecular Atlas of Lung Development Program. American Journal of Physiology: Lung Cellular and Molecular Physiology. 2017; 313:L733-L740.

Ahlfeld, SK; Perl, AK. A "GLI-tch " in Alveolar Myofibroblast Differentiation. American Journal of Respiratory Cell and Molecular Biology. 2017; 57:261-262.

Endale, M; Ahlfeld, S; Bao, E; Chen, X; Green, J; Bess, Z; Weirauch, M; Xu, Y; Perl, AK. Dataset on transcriptional profiles and the developmental characteristics of PDGFRα expressing lung fibroblasts. Data in Brief. 2017; 13:415-431.

Endale, M; Ahlfeld, S; Bao, E; Chen, X; Green, J; Bess, Z; Weirauch, MT; Xu, Y; Perl, AK. Temporal, spatial, and phenotypical changes of PDGFR alpha expressing fibroblasts during late lung development. Developmental Biology. 2017; 425:161-175.

Du, Y; Kitzmiller, JA; Sridharan, A; Perl, AK; Bridges, JP; Misra, RS; Pryhuber, GS; Mariani, TJ; Bhattacharya, S; Guo, M; et al. Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development. Thorax. 2017; 72:481-484.

Cox, AM; Gao, Y; Perl, AT; Tepper, RS; Ahlfeld, SK. Cumulative Effects of Neonatal Hyperoxia on Murine Alveolar Structure and Function. Pediatric Pulmonology. 2017; 52:616-624.

Xu, Y; Mizuno, T; Sridharan, A; Du, Y; Guo, M; Tang, J; Wikenheiser-Brokamp, KA; Perl, AT; Funari, VA; Gokey, JJ; et al. Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. JCI insight. 2016; 1.

Ustiyan, V; Zhang, Y; Perl, AT; Whitsett, JA; Kalin, TV; Kalinichenko, VV. beta-Catenin and Kras/Foxm1 Signaling Pathway Are Critical to Restrict Sox9 in Basal Cells During Pulmonary Branching Morphogenesis. Developmental Dynamics. 2016; 245:590-604.

Green, J; Endale, M; Auer, H; Perl, AK T. Diversity of interstitial lung fibroblasts is regulated by platelet-derived growth factor receptor a kinase activity. American Journal of Respiratory Cell and Molecular Biology. 2016; 54:532-545.