The Immune Deficiency and Histiocytosis Program offers a wide range of treatment options for diseases involving the immune system. These therapies include medications, chemotherapy, hematopoietic (blood or marrow) stem cell transplantation, immunoglobulin therapy, plasma exchange and home-based therapies.

Our team may also consider if you will benefit from new, emerging or experimental options that have already shown promising results in other patients.

Children can receive treatment at Cincinnati Children’s on an inpatient or outpatient basis, or return home to the care of their referring physician. Our team is always available to consult with families and their physician.

Genetic Testing

The care team works closely with technicians in the Molecular Genetics Laboratory at Cincinnati Children’s. These technicians perform tests that help confirm diagnoses and determine whether an immune deficiency disorder has a genetic cause.

Genetic counselors familiar with immune system diseases such as hemophagocytic lymphohistiocytosis (HLH) are available to meet with families to talk about what the results might mean. Results also help the care team refine the treatment plan.