A photo of David Neal Franz.

Founding Director, Tuberous Sclerosis Clinic

Associate Director of Clinical Affairs, Division of Neurology

Professor, UC Department of Pediatrics



Board Certified

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My Biography & Research


David Neal Franz, MD, was born and raised in Dayton, Ohio. He received his undergraduate degree in history and literature from Earlham College in Richmond, Indiana.

After completing his training, he served as assistant professor of neurology and pediatrics at Wright State University before returning to Cincinnati Children's Hospital Medical Center.

He established the Cincinnati Tuberous Sclerosis Clinic in 1992, to assist in the medical care of patients who have or are suspected of having tuberous sclerosis.

Additional Languages


Clinical Interests

Tuberous sclerosis (adults and children); neuropharmacology; neurocutaneous disorders; general pediatric neurology

Academic Affiliation

Professor, UC Department of Pediatrics


Neurology, Tuberous Sclerosis, Sturge-Weber Syndrome, Neurology

My Locations

  • Mason


    9560 Children's Drive
    Mason, Ohio 45040

My Education

MD: Ohio State University College of Medicine, Columbus, OH, 1985.

Residency: Wright State University Affiliated Hospitals, Dayton, OH.

Fellowship: Children's Hospital Medical Center, Cincinnati, OH.

Certification: Pediatrics, 1990, 2016; Neurology with special competence in child neurology, 1992.

My Publications

Effect of everolimus on renal function in patients with tuberous sclerosis complex: evidence from EXIST-1 and EXIST-2. Bissler, JJ; Budde, K; Sauter, M; Franz, DN; Zonnenberg, BA; Frost, MD; Belousova, E; Berkowitz, N; Ridolfi, A; Kingswood, JC. Nephrology Dialysis Transplantation. 2019; 34:1000-1008.

Lymphangioleiomyomatosis Mortality in Patients with Tuberous Sclerosis Complex. Zak, S; Mokhallati, N; Su, W; McCormack, FX; Franz, DN; Mays, M; Krueger, DA; Szczesniak, RD; Gupta, N. Annals of the American Thoracic Society. 2019; 16:509-512.

Longitudinal Effects of Everolimus on White Matter Diffusion in Tuberous Sclerosis Complex. Peters, JM; Prohl, A; Kapur, K; Nath, A; Scherrer, B; Clancy, S; Prabhu, SP; Sahin, M; Franz, DN; Warfield, SK; et al. Pediatric Neurology. 2019; 90:24-30.

Short-term safety of mTOR inhibitors in infants and very young children with tuberous sclerosis complex (TSC): Multicentre clinical experience. Krueger, DA; Capal, JK; Curatolo, P; Devinsky, O; Ess, K; Tzadok, M; Koenig, MK; Narayanan, V; Ramos, F; Jozwiak, S; et al. European Journal of Paediatric Neurology. 2018; 22:1066-1073.

Effect of everolimus on skin lesions in patients treated for subependymal giant cell astrocytoma and renal angiomyolipoma: final 4-year results from the randomized EXIST-1 and EXIST-2 studies. Franz, DN; Budde, K; Kingswood, JC; Belousova, E; Sparagana, S; de Vries, PJ; Berkowitz, N; Ridolfi, A; Bissler, JJ. Journal of the European Academy of Dermatology and Venereology. 2018; 32:1796-1803.

mTOR inhibitor therapy as a disease modifying therapy for tuberous sclerosis complex. Franz, DN; Krueger, DA. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 2018; 178:365-373.

Measuring Health-Related Quality of Life in Tuberous Sclerosis Complex - Psychometric Evaluation of Three Instruments in Individuals With Refractory Epilepsy. de Vries, PJ; Franz, DN; Curatolo, P; Nabbout, R; Neary, M; Herbst, F; Sully, K; Brohan, E; Bennett, B; Lawson, JA. Frontiers in Pharmacology. 2018; 9.

Thoracoabdominal imaging of tuberous sclerosis. Morin, CE; Morin, NP; Franz, DN; Krueger, DA; Trout, AT; Towbin, AJ. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2018; 48:1307-1323.

Calcification in cerebral parenchyma affects pharmacoresistant epilepsy in tuberous sclerosis. Zhang, M; Zou, L; Wang, Y; Pang, L; Ma, S; Huang, L; Gao, Y; Lu, Q; Franz, DN. Seizure-European Journal of Epilepsy. 2018; 60:86-90.

Everolimus dosing recommendations for tuberous sclerosis complex-associated refractory seizures. Franz, DN; Lawson, JA; Yapici, Z; Brandt, C; Kohrman, MH; Wong, M; Milh, M; Wiemer-Kruel, A; Voi, M; Coello, N; et al. Epilepsia. 2018; 59:1188-1197.