A photo of David Neal Franz.

David Neal Franz, MD

  • Founding Director, Tuberous Sclerosis Clinic
  • Associate Director of Clinical Affairs, Division of Neurology
  • Professor, UC Department of Pediatrics
I believe in providing the best care and treatment for my patients and families, whatever that may be.



As a brain doctor, I care for children with general neurologic conditions. I specialize in neurocutaneous disorders and neuropharmacology. I’m the founding director of the Tuberous Sclerosis Clinic at Children’s Hospital Medical Center.

I believe in providing the best care and treatment for my patients and families, whatever that may be.

At Cincinnati Children’s we try our sincere best to help patients and families living with a complex neurological and medical diagnosis. Many of these conditions do not have established or approved therapies.

My research focuses on targeted therapies for epilepsy and genetic brain disorders.

Additional Languages



Insurance Information

Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.

View Insurance Information


Prenatal Sirolimus Treatment for Rhabdomyomas in Tuberous Sclerosis. Ebrahimi-Fakhari, D; Stires, G; Hahn, E; Krueger, D; Franz, DN. Pediatric Neurology. 2021; 125:26-31.

Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations. Northrup, H; Aronow, ME; Bebin, EM; Bissler, J; Darling, TN; de Vries, PJ; Frost, MD; Fuchs, Z; Gosnell, ES; Gupta, N; et al. Pediatric Neurology. 2021; 123:50-66.

Diabetes in Individuals With Tuberous Sclerosis Complex Treated With mTOR Inhibitors. Agricola, K; Stires, G; Krueger, DA; Capal, JK; Franz, DN; Ritter, DM. Pediatric Neurology. 2021; 120:7-10.

Lymphangioleiomyomatosis Association with Underlying Genotype in Patients with Tuberous Sclerosis Complex. Tian, X; Glass, JE; Kwiatkowski, DJ; Towbin, AJ; Li, Y; Sund, KL; Krueger, DA; Franz, DN; McCormack, FX; Gupta, N. Annals of the American Thoracic Society. 2021; 18:815-819.

Frequency, Progression, and Current Management: Report of 16 New Cases of Nonfunctional Pancreatic Neuroendocrine Tumors in Tuberous Sclerosis Complex and Comparison With Previous Reports. Mowrey, K; Northrup, H; Rougeau, P; Hashmi, SS; Krueger, DA; Ebrahimi-Fakhari, D; Towbin, AJ; Trout, AT; Capal, JK; Franz, DN; et al. Frontiers in Neurology. 2021; 12.

mTOR Inhibitor Therapy for Tuberous Sclerosis Complex: Longitudinal Study of Muscle Mass Determined by Abdominal Cross-sectional Imaging with CT and MRI. Raab, C; Gilligan, LA; Trout, AT; Krueger, DA; Franz, DN; Zhang, B; Towbin, AJ. Radiology. Imaging cancer. 2020; 2.

Pharmacological treatment strategies for subependymal giant cell astrocytoma (SEGA). Ebrahimi-Fakhari, D; Franz, DN. Expert Opinion on Pharmacotherapy. 2020; 21:1329-1336.

Cannabidiol Elevates Mechanistic Target of Rapamycin Inhibitor Levels in Patients With Tuberous Sclerosis Complex. Ebrahimi-Fakhari, D; Agricola, KD; Tudor, C; Krueger, D; Franz, DN. Pediatric Neurology. 2020; 105:59-61.

Congenital Lymphatic Malformation and Aortic Aneurysm in a Patient with TSC2 Mutation. Wiemer-Kruel, A; Mayer, H; Ewert, P; Martinoff, S; Eckstein, H; Kriebel, T; Bissler, J; Franz, D; Bast, T. Neuropediatrics. 2020; 51:57-61.

Clinical Letter: A case report of targeted therapy with sirolimus for NPRL3 epilepsy. Vawter-Lee, M; Franz, DN; Fuller, CE; Greiner, HM. Seizure : the journal of the British Epilepsy Association. 2019; 73:43-45.

Patient Ratings and Comments

All patient satisfaction ratings and comments are submitted by actual patients and verified by a leading independent patient satisfaction company, NRC Health. Patient identities are withheld to ensure confidentiality and privacy. Only those providers whose satisfaction surveys are administered through Cincinnati Children’s Hospital Medical Center are displayed. Click here to learn more about our survey