A photo of John Greinwald Jr.

John H. Greinwald Jr., MD, FAAP

  • Professor, UC Department of Pediatrics
  • UC Department of Otolaryngology – Head & Neck Surgery
  • Board Certified



Hearing loss in infants and children can be temporary or permanent. It can be caused by head infections, trauma, exposure to loud noise and some types of medical therapies. There is a significant genetic component associated with hearing loss.

My research aims to uncover the connections between genetics and hearing loss. Throughout my investigations, I seek to understand the genetic basis of hearing loss. In addition to my research work, I’m a pediatric ear, nose and throat (ENT)/otologist at Cincinnati Children's Hospital Medical Center and Professor of Otolaryngology Head and Neck Surgery at the University of Cincinnati.

I was first inspired to become a pediatric ENT surgeon during residency. When working with children, my mentor Dr. Craig Derkay, a pediatric ENT surgeon and a director of pediatric otolaryngology, inspired me. I pursued my research interests when I trained under my mentor Dr. Richard Smith during my pediatric ENT fellowship. These mentors encouraged and supported my career in Otolaryngology, Otology and Genetics.

I have more than 23 years of experience in the ENT field. My research has been published in respected journals, such as Journal of Child Neurology, Genetics in Medicine, International Journal of Pediatric Otorhinolaryngology, Journal of the American Academy of Audiology, Otology and Neurotology, Otolaryngology Head and Neck Surgery and The Laryngoscope.

BS: Wofford College, Spartanburg, SC, 1983.

MD: Medical University of South Carolina, Charleston, SC, 1987.

Internship: Naval Medical Center, Portsmouth, VA, 1988.

Residency: Naval Medical Center, Portsmouth, VA, 1995.

Fellowship: Pediatric Otolaryngology, University of Iowa, Iowa City, IA, 1998.

Services and Specialties

Genetics, Otolaryngology ENT, Cochlear Implant, Ear and Hearing, Genetic Testing for Hearing Loss

Research Areas


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The Girl With the Bleeding Earlobe Mass. Nistel, M; Lee, SH; Born, H; Greinwald, JH; Abdaljaleel, M; Sobolewski, B. Pediatric Emergency Care. 2021; 37:e1718-e1720.

Disease-specific ACMG/AMP guidelines improve sequence variant interpretation for hearing loss. Patel, MJ; DiStefano, MT; Oza, AM; Hughes, MY; Wilcox, EH; Hemphill, SE; Cushman, BJ; Grant, AR; Siegert, RK; Shen, J; Yamazawa, K; Yuan, HJ; Black-Zeigelbein, E; Zhang, K. Genetics in Medicine. 2021; 23:2208-2212.

Cortical processing of location and frequency changes of sounds in normal hearing listeners. Zhang, F; McGuire, K; Firestone, G; Dalrymple, K; Greinwald, J; Fu, QJ. Hearing Research. 2021; 400:108110.

Socioeconomic Disparities in Pediatric Single-Sided Deafness. Lipschitz, N; Kohlberg, GD; Scott, M; Smith, MM; Jr, GJ H. Otolaryngology - Head and Neck Surgery. 2020; 163:829-834.

How Strong Is the Duty to Treat in a Pandemic? Ethics in Practice: Point-Counterpoint. Redmann, AJ; Manning, A; Kennedy, A; Greinwald, JH; deAlarcon, A. Otolaryngology - Head and Neck Surgery. 2020; 163:325-327.

Imaging findings in pediatric single-sided deafness and asymmetric hearing loss. Lipschitz, N; Kohlberg, GD; Scott, M; Jr, GJ H. The Laryngoscope. 2020; 130:1007-1010.

The Clinical Journey of Patients with Riboflavin Transporter Deficiency Type 2. Amir, F; Atzinger, C; Massey, K; Greinwald, J; Hunter, LL; Ulm, E; Kettler, M. Journal of Child Neurology. 2020; 35:283-290.

International Pediatric Otolaryngology Group (IPOG) Consensus Recommendations: Congenital Cholesteatoma. Denoyelle, F; Simon, F; Chang, KW; Chan, KH; Cheng, AG; Cheng, AT; Choo, DI; Daniel, SJ; Farinetti, A; Garabedian, E; Triglia, J; Walton, J; Zalzal, G; Leboulanger, N. Otology and Neurotology: an international forum. 2020; 41:345-351.

Consensus interpretation of the p.Met34Thr and p.Val37Ile variants in GJB2 by the ClinGen Hearing Loss Expert Panel. Shen, J; Oza, AM; del Castillo, I; Duzkale, H; Matsunaga, T; Pandya, A; Kang, HP; Mar-Heyming, R; Guha, S; Moyer, K; Yuan, H; Mutai, H; Schimmenti, L; Grp, CH L W. Genetics in Medicine. 2019; 21:2442-2452.

ClinGen expert clinical validity curation of 164 hearing loss gene-disease pairs. DiStefano, MT; Hemphill, SE; Oza, AM; Siegert, RK; Grant, AR; Hughes, MY; Cushman, BJ; Azaiez, H; Booth, KT; Chapin, A; Yuan, H; Black-Zeigelbein, E; Zhang, K; Doma, CH L C. Genetics in Medicine. 2019; 21:2239-2247.

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