Trent R. Hummel, MD

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Co-Medical Director, Brain Tumor Center
Professor, UC Department of Pediatrics

trent.hummel@cchmc.org
Board Certified

Liberty Campus
Burnet Campus

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About

Biography

I completed my graduate medical training at the University of Cincinnati College of Medicine, residency training in pediatrics at Children's Hospital Medical Center of Akron, and pediatric hematology/oncology training at Cincinnati Children's Hospital Medical Center. Currently, I serve as an associate professor of pediatrics at Cincinnati Children's within the University of Cincinnati.

As a pediatric neuro-oncologist, I care for children and families affected by brain and spinal cord tumors and specialize in developing new therapies for central nervous system cancers. I am a member of the Central Nervous System (Brain Tumor) Committee in the Children's Oncology Group (COG) and the co-principal investigator for the Pediatric Brain Tumor Consortium (PBTC) at Cincinnati Children's. My work is dedicated to developing novel therapeutics to treat children with all central nervous system tumors, including those with neurofibromatosis type 1 and 2 related CNS tumors and very poor prognosis tumors such as high-grade gliomas and diffuse intrinsic pontine gliomas.

Services and Specialties

Research Areas

Locations (2)

Liberty Campus

7777 Yankee Rd
Liberty Township, OH 45044

Burnet Campus

3333 Burnet Ave
Cincinnati, OH 45229

Insurance Information

Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.

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Publications

A CAR-T Tonic Signaling Code Predicts Anti-Tumor Efficacy in Diffuse Midline Glioma. Deng, B; Zhong, X; Xin, D; Huang, X; Soni, UK; Ma, W; Cai, M; Liang, P-Y; Bai, J; Qin, Q; Koschmann, C; Cancelas, JA; Zheng, Y; Lu, QR. Neuro-Oncology. 2026.

ID #476 Increased Prevalence of Optic Nerve Hypoplasia in Neurofibromatosis Type 1. Rawashdeh, M; Gilene, S; Hummel, T; Smiley, NP; Graham, R; Mochizuki, A; Raskin, S; Shah, V; De Blank, P. Neuro-Oncology Pediatrics. 2026; 2(Supplement_1):wuag026.170.

ID #1028 A Retrospective Review Characterizing the Toxicities, Outcomes, and Molecular Characteristics of Adolescent and Young Adult Patients with Medulloblastoma. Reiff, S; Cronk, J; Graham, R; Hummel, T; Mochizuki, A; Smiley, NP; De Blank, P; Raskin, S. Neuro-Oncology Pediatrics. 2026; 2(Supplement_1):wuag026.457.

ID #1002 Hematologic Toxicity during Proton Radiation: a Review of Weekly CBC Results at a Single Center. Miller, C; Camardo, H; Fohl, D; Davis, J; Hummel, T; Mochizuki, A; Smiley, NP; Graham, R; Raskin, S; Frankart, A; Pater, L; De Blank, P. Neuro-Oncology Pediatrics. 2026; 2(Supplement_1):wuag026.440.

ID #112 PAEDNEOVAX - Multicentre, investigator-initiated phase I/II study to assess safety and efficacy of personalised mRNA vaccine targetting tumour-associated neoantigens in children and young adults with high-risk brain tumours. Hansford, J; Valvi, S; Dodgshun, A; Manoharan, N; Moore, C; Hassall, T; De Luca, C; Dawes, L; Goldstein, R; Waddell, N; Olsen, K; Dube, C; Orozco, NM; Wainwright, B. Neuro-Oncology Pediatrics. 2026; 2(Supplement_1):wuag026.021.

Multi-Institutional Annotated Multiparametric MRI Dataset of Pediatric High-Grade Gliomas. Kazerooni, AF; Jiang, Z; Gandhi, D; Khalili, N; Liu, X; Tu, W; Ware, JB; Familiar, AM; Vunnava, B; Zapaishchykova, A; Resnick, AC; Nabavizadeh, A; Vossough, A; Linguraru, MG. Radiology: Artificial Intelligence. 2026; 8(3):e250902.

MEK inhibitor-induced dropped head syndrome in pediatrics. Gilene, S; Miller, C; Cronk, JC; Graham, RT; Gross, AM; Hummel, TR; Kotch, C; Mochizuki, AY; Raskin, S; Pillay-Smiley, N; De Blank, P. Neuro-Oncology Pediatrics. 2026; 2(2):wuag024.

Re-irradiation practices and outcomes in patients with diffuse intrinsic pontine glioma (DIPG): A report from the International DIPG/DMG Registry. Smiley, NP; Lane, A; Webster, A; Blank, C; Hawkins, C; Hassall, T; Leach, J; Dorris, K; Jones, B; Hansford, JR; Zaghloul, M; Cheng, S; Hummel, TR; Hoffman, LM; Warren, KE. Neuro-Oncology Pediatrics. 2026; 2(2):wuag013.

IMMU-40. Robust activation and clonal expansion of early, non-exhausted, stem-like endogenous T cells induced by chemo-immunotherapy treatment in patients with pediatric brain tumors is predictive of clinical outcome. Johnson, TS; Pacholczyk, R; Satpathy, S; Berrong, Z; Chien, F; Huang, C; Thomas, BE; N, S; Baird, L; Sadek, RF; Yeo, KK; Macdonald, TJ; Bhasin, MK; Munn, DH. Neuro-Oncology. 2025; 27(Supplement_5):v211-v212.

BraTS-PEDs: Results of the Multi-Consortium International Pediatric Brain Tumor Segmentation Challenge 2023. Fathi Kazerooni, A; Khalili, N; Liu, X; Haldar, D; Jiang, Z; Zapaishchykova, A; Pavaine, J; Shah, LM; Jones, BV; Sheth, N; Resnick, A; Bakas, S; Vossough, A; Linguraru, MG. MELBA journal. 2025; 2025(June 2025):72-87.

From the Blog

Blog Cancer and Blood Diseases

NJoyitAll Camp: Can’t Wait for Another Summer

By Trent R. Hummel, MD3/13/2019

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