A photo of William D. Hardie.

Member, Division of Pulmonary Medicine

Professor, UC Department of Pediatrics

513-636-6771

513-636-4615

"Going into pediatrics was a natural choice, as working with children is its own reward."

My Biography & Research

Biography

As a pediatric pulmonologist for over 25 years, I have broad experience in many facets of pediatric pulmonary medicine. I enjoy the wide variety of challenges in the patients I see, ranging from wheezing, chronic cough, sleep disorders and recurrent pneumonia, and feel deeply rewarded when I improve the health of children. In additional to my general pulmonary expertise, I am a co-founder of Cincinnati Children’s Cardiorespiratory Sports Clinic which evaluates and treats children and young adults who have shortness of breath or chest pain with exercise. I also initiated a collaborative effort with physicians in surgery and emergency medicine to manage children and young adults who develop primary spontaneous pneumothorax, an abnormal accumulation of air in the space between the lungs and the chest cavity (the pleural space).

Going into pediatrics was a natural choice, as working with children is its own reward. As a student, I remember a pediatrician telling me he liked pediatrics because he felt it made him younger — now that I’m older, I can see he was right. I was drawn to pulmonary medicine during medical school because I enjoyed the respiratory system physiology and research challenges and especially the opportunity to develop longitudinal relationships with patients and families.

In addition to caring for patients I have maintained a basic science laboratory focused on pulmonary fibrosis, which is scarring of the lung. My colleagues and I seek to identify the proteins and cellular pathways associated with this disorder and explore potential novel treatments. We are currently focused on a rare lung fibrosis condition called pleuroparenchymal fibroelastosis which can afflict both children and adults. As a clinician and a scientist I have a developed a stronger appreciation for the vital importance of clean air in preserving child health and am involved with state and national organizations advocating for improving air quality.

My wife and I purchased a small “farmette” located between Mason and Lebanon, Ohio where we raised our three children. One of my hobbies is growing fruit trees and making maple and walnut syrup in the winter. I was born and raised in Wilmington, Ohio where as a boy I worked for the Cincinnati Bengals during their summer training camps at Wilmington College. Feel free to drop by and shout out a “Who Dey” if you come to my clinic!

Clinical Interests

General pediatric pulmonary with additional expertise in managing children with recurrent pneumonia, pneumothorax, pectus excavatum and shortness of breath with exercise

Research Interests

Pulmonary fibrosis

Academic Affiliation

Professor, UC Department of Pediatrics

Clinical Divisions

Pulmonary Medicine, Home Ventilator, Pulmonary Function

Research Divisions

Pulmonary Medicine

My Education

MD: Vanderbilt University, Nashville, TN, 1990.

Residency: Children's Hospital Medical Center, Cincinnati, OH.

Fellowship: Children's Hospital Medical Center, Cincinnati, OH.

Certification: Pediatrics, 1993; Pulmonary Medicine, 1999.

My Publications

Ventilatory limitations are not associated with dyspnea on exertion or reduced aerobic fitness in pectus excavatum. Hardie, W; Powell, AW; Jenkins, TM; Foster, K; Tretter, JT; Fleck, RJ; Garcia, VF; Brown, RL. Pediatric Pulmonology. 2021; 56:2911-2917.

The Severity of Pectus Excavatum Defect Is Associated With Impaired Cardiopulmonary Function. Zens, TJ; Casar Berazaluce, AM; Jenkins, TM; Hardie, W; Alsaied, T; Tretter, JT; Moore, R; Foster, K; Fleck, RJ; Hanke, RE; et al. Annals of Thoracic Surgery. 2021.

An evidence-based review of primary spontaneous pneumothorax in the adolescent population. Wilson, PM; Rymeski, B; Xu, X; Hardie, W. Journal of the American College of Emergency Physicians Open. 2021; 2.

The chest wall gender divide: females have better cardiopulmonary function and exercise tolerance despite worse deformity in pectus excavatum. Casar Berazaluce, AM; Jenkins, TM; Garrison, AP; Hardie, WD; Foster, KE; Alsaied, T; Tretter, J; Moore, RA; Fleck, RJ; Garcia, VF; et al. Pediatric Surgery International. 2020; 36:1281-1286.

COVID-19, Climate Change, and the American Thoracic Society. A Shared Responsibility. Shankar, HM; Ewart, G; Garcia, E; Hicks, A; Hardie, W. Annals of the American Thoracic Society. 2020; 17:1052-1055.

Black walnut tree syrup is not allergenic in individuals with a documented walnut allergy. Lierl, M; Assa'ad, A; Jennings, J; Farrell, M; Hardie, WD. Journal of Allergy and Clinical Immunology: In Practice. 2020; 8:2096-2097.

Respiratory Medications in Infants <29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium. Ryan, RM; Keller, RL; Poindexter, BB; D'Angio, CT; Shaw, PA; Bellamy, SL; Moore, PE; McPherson, C; Greenberg, JM; Chougnet, C; et al. Journal of Pediatrics. 2019; 208:148-155.e3.

Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia. Ryan, RM; Feng, R; Bazacliu, C; Ferkol, TW; Ren, CL; Mariani, TJ; Poindexter, BB; Wang, F; Moore, PE; Chougnet, C; et al. Journal of Pediatrics. 2019; 207:130-135.e2.

Longitudinal free-breathing MRI measurement of murine lung physiology in a progressive model of lung fibrosis. Guo, J; Hardie, WD; Cleveland, ZI; Davidson, C; Xu, X; Madala, SK; Woods, JC. Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 2019; 126:1138-1149.

Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth. Hamvas, A; Feng, R; Bi, Y; Wang, F; Bhattacharya, S; Mereness, J; Kaushal, M; Cotten, CM; Ballard, PL; Mariani, TJ; et al. BMC Genetics. 2018; 19.