A photo of Theodosia A. Kalfa.

Co-Director, Erythrocyte Diagnostic Laboratory

Associate Professor, UC Department of Pediatrics



Board Certified

My Biography & Research

Additional Languages


Research Interests

Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species

Academic Affiliation

Associate Professor, UC Department of Pediatrics


Cancer and Blood Diseases, Sickle Cell and Hemoglobin Disorders, Experimental Hematology and Cancer Biology, Hematology, Cancer and Blood Diseases

My Locations

My Education

MD: Aristotle University Medical School, Thessaloniki, Greece, 1990.

PhD: Aristotle University Medical School, Thessaloniki, Greece, 1997.

Residency: University Of North Carolina, Chapel Hill, NC, 1999.

Fellowship: Duke University Medical Center, Durham, NC, 2003.

Certification: Hematology / oncology, American Board of Pediatrics, 2004; Pediatrics, American Board of Pediatrics, 2000; ECFMG Certification, 1995.

Licenses: Full and unrestricted medical license (OH Medical Board), 2003-present; full and unrestricted license of medical practice in Greece, 1990-present.

My Publications

How I approach hereditary hemolytic anemia and splenectomy. Rothman, JA; Stevens, JL; Gray, FL; Kalfa, TA. Pediatric Blood and Cancer. 2020.

Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia. McGann, PT; Niss, O; Dong, M; Marahatta, A; Howard, TA; Mizuno, T; Lane, A; Kalfa, TA; Malik, P; Quinn, CT; et al. American Journal of Hematology. 2019; 94:871-879.

The Spectrum of SPTA1-Associated Hereditary Spherocytosis. Chonat, S; Risinger, M; Sakthivel, H; Niss, O; Rothman, JA; Hsieh, L; Chou, ST; Kwiatkowski, JL; Khandros, E; Gorman, MF; et al. Frontiers in Physiology. 2019; 10.

Rare Hereditary Hemolytic Anemias Diagnostic Approach and Considerations in Management. Risinger, M; Emberesh, M; Kalfa, TA. Hematology/Oncology Clinics of North America. 2019; 33:373-392.

Hereditary elliptocytosis-associated alpha-spectrin mutation p.L155dup as a modifier of sickle cell disease severity. Risinger, M; Christakopoulos, GE; Schultz, CL; McGann, PT; Zhang, W; Kalfa, TA. Pediatric Blood and Cancer. 2019; 66:e27531-e27531.

Addressing the diagnostic gaps in pyruvate kinase deficiency: Consensus recommendations on the diagnosis of pyruvate kinase deficiency. Bianchi, P; Fermo, E; Glader, B; Kanno, H; Agarwal, A; Barcellini, W; Eber, S; Hoyer, JD; Kuter, DJ; Maia, TM; et al. American Journal of Hematology. 2019; 94:149-161.

Congenital dyserythropoietic anaemia type I diagnosed in a young adult with a history of splenectomy in childhood for presumed haemolytic anaemia. Chonat, S; McLemore, ML; Bunting, ST; Nortman, S; Zhang, K; Kalfa, TA. British Journal of Haematology. 2018; 182:10-10.

Hereditary xerocytosis: Diagnostic considerations. Risinger, M; Glogowska, E; Chonat, S; Zhang, K; Dagaonkar, N; Joiner, CH; Quinn, CT; Kalfa, TA; Gallagher, PG. American Journal of Hematology. 2018; 93:E67-E69.

Alu element insertion in PKLR gene as a novel cause of pyruvate kinase deficiency in Middle Eastern patients. Lesmana, H; Dyer, L; Li, X; Denton, J; Griffiths, J; Chonat, S; Seu, KG; Heeney, MM; Zhang, K; Hopkin, RJ; et al. Human Mutation. 2018; 39:389-393.

Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models. Wang, J; Hayashi, Y; Yokota, A; Xu, Z; Zhang, Y; Huang, R; Yan, X; Liu, H; Ma, L; Azam, M; et al. Haematologica: the hematology journal. 2018; 103:69-79.