Theodosia A. Kalfa, MD, PhD
- Co-Director, Erythrocyte Diagnostic Laboratory
- Professor, UC Department of Pediatrics
- theodosia.kalfa@cchmc.org
- Board Certified
About
MD: Aristotle University Medical School, Thessaloniki, Greece, 1990.
PhD: Aristotle University Medical School, Thessaloniki, Greece, 1997.
Residency: University Of North Carolina, Chapel Hill, NC, 1999.
Fellowship: Duke University Medical Center, Durham, NC, 2003.
Certification: Hematology / oncology, American Board of Pediatrics, 2004; Pediatrics, American Board of Pediatrics, 2000; ECFMG Certification, 1995.
Licenses: Full and unrestricted medical license (OH Medical Board), 2003-present; full and unrestricted license of medical practice in Greece, 1990-present.
Interests
Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species
Additional Languages
Greek
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. The American Journal of Human Genetics. 2020; 107:1149-1156.
Red cell membrane disorders: structure meets function. Blood. 2020; 136:1250-1261.
Signaling and cytoskeletal requirements in erythroblast enucleation. Blood. 2012; 119:6118-6127.
G-CSF resistance of ELANE-mutant neutropenia depends on SERF1-containing truncated-neutrophil elastase aggregates. The Journal of Clinical Investigation. 2025; 135:e177342.
Three-generation female cohort with macrocytic anemia and iron overload. American Journal of Hematology. 2025; 100:133-138.
Loss of ATG5 in Humans Causes Syndromic Congenital Dyserythropoietic Anemia with Impaired Mitophagy in Late Stages of Terminal Erythropoiesis. Blood. 2024; 144:1084.
The Dominant Negative Acting VPS4AE228Q Mutation Causes Dyserythropoiesis in Human iPSC-Derived Erythroblast Cultures That Phenocopies Cimdag Syndrome-Associated Anemia. Blood. 2024; 144:2458.
Heterogeneity of the Erythromyeloblastic Island (EMBI) Niche during Baseline and Stress Erythropoiesis. Blood. 2024; 144:163.
Inducible, Erythroid-Specific Knockout of Codanin-1 in Adult Mice Replicates Congenital Dyserythropoietic Anemia Type-Ia. Blood. 2024; 144:1071.
A pharmacokinetic-pharmacodynamic analysis of l-glutamine for the treatment of sickle cell disease: Implications for understanding the mechanism of action and evaluating response to therapy. British Journal of Haematology. 2024; 205:1147-1158.
From the Blog
Blood Cell Production Discovery Opens Path to Improve Anemia of Inflammation
Theodosia A. Kalfa, MD, PhD10/31/2022
Rare Disease Day: More Tools for Solving Diagnostic Mysteries
Theodosia A. Kalfa, MD, PhD3/1/2021
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