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MD: Aristotle University Medical School, Thessaloniki, Greece, 1990.
PhD: Aristotle University Medical School, Thessaloniki, Greece, 1997.
Residency: University Of North Carolina, Chapel Hill, NC, 1999.
Fellowship: Duke University Medical Center, Durham, NC, 2003.
Certification: Hematology / oncology, American Board of Pediatrics, 2004; Pediatrics, American Board of Pediatrics, 2000; ECFMG Certification, 1995.
Licenses: Full and unrestricted medical license (OH Medical Board), 2003-present; full and unrestricted license of medical practice in Greece, 1990-present.
Cancer and Blood Diseases, Sickle Cell and Hemoglobin Disorders
Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species
Experimental Hematology and Cancer Biology, Hematology, Cancer and Blood Diseases
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VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects.
Seu, KG; Trump, LR; Emberesh, S; Lorsbach, RB; Johnson, C; Meznarich, J; Underhill, HR; Chou, ST; Sakthivel, H; Nassar, NN; et al.
American Journal of Human Genetics.
Red cell membrane disorders: structure meets function.
Risinger, M; Kalfa, TA.
Signaling and cytoskeletal requirements in erythroblast enucleation.
Konstantinidis, DG; Pushkaran, S; Johnson, JF; Cancelas, JA; Manganaris, S; Harris, CE; Williams, DA; Zheng, Y; Kalfa, TA.
Diagnosis and clinical management of red cell membrane disorders.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program.
Characterizing bulk rigidity of rigid red blood cell populations in sickle-cell disease patients.
Gutierrez, M; Shamoun, M; Seu, KG; Tanski, T; Kalfa, TA; Eniola-Adefeso, O.
SERF1 Is Required for G-CSF Resistance of Start-Codon Mutant ELANE Granulocytic Precursors.
Nayak, RC; Trump, L; Emberesh, S; Lee, Y; Singh, AK; Wellendorf, AM; Horwitz, MS; Kalfa, TA; Lutzko, C; Cancelas, JA.
Overexpression of Human TLR8 Causes Fatal Anemia in SLE-Prone Mice By Altering the Bone Marrow Erythropoietic Niche.
Davidson, A; Maria, N; Papoin, J; Raparia, C; Sun, Z; Zhang, W; Kalfa, TA; Paulson, R; Blanc, L.
Activation of Pyruvate Kinase-R with Etavopivat (FT-4202) Is Well Tolerated, Improves Anemia, and Decreases Intravascular Hemolysis in Patients with Sickle Cell Disease Treated for up to 12 Weeks.
Brown, RC C; Saraf, SL; Cruz, K; Idowu, M; Kalfa, TA; Geib, J; Forsyth, S; Schroeder, P; Wu, E; Kelly, P; et al.
Etavopivat, an Allosteric Activator of Pyruvate Kinase-R, Improves Sickle RBC Functional Health and Survival and Reduces Systemic Markers of Inflammation and Hypercoagulability in Patients with Sickle Cell Disease: An Analysis of Exploratory Studies in a Phase 1 Study.
Kalfa, TA; Telen, MJ; Saraf, SL; Brown, RC C; Giger Seu, K; Larkin, SK; Ribadeneira, MD; Schroeder, P; Wu, E; Kelly, P; et al.
Trial in Progress: A Phase 2, Open-Label Study Evaluating the Safety and Efficacy of the PKR Activator Etavopivat (FT-4202) in Patients with Thalassemia or Sickle Cell Disease.
Lal, A; Brown, RC C; Coates, TD; Kalfa, TA; Kwiatkowski, JL; Brevard, J; Potter, V; Wood, KW; Sheth, S.
Theodosia A. Kalfa, MD, PhD, Loren DM Pena, MD, PhD3/1/2021
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