A photo of Theodosia A. Kalfa.

Co-Director, Erythrocyte Diagnostic Laboratory

Professor, UC Department of Pediatrics



Board Certified

My Biography & Research

Additional Languages


Research Interests

Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species

Academic Affiliation

Professor, UC Department of Pediatrics

Clinical Divisions

Cancer and Blood Diseases, Sickle Cell and Hemoglobin Disorders

Research Divisions

Experimental Hematology and Cancer Biology, Hematology, Cancer and Blood Diseases

Blog Posts

My Locations

My Education

MD: Aristotle University Medical School, Thessaloniki, Greece, 1990.

PhD: Aristotle University Medical School, Thessaloniki, Greece, 1997.

Residency: University Of North Carolina, Chapel Hill, NC, 1999.

Fellowship: Duke University Medical Center, Durham, NC, 2003.

Certification: Hematology / oncology, American Board of Pediatrics, 2004; Pediatrics, American Board of Pediatrics, 2000; ECFMG Certification, 1995.

Licenses: Full and unrestricted medical license (OH Medical Board), 2003-present; full and unrestricted license of medical practice in Greece, 1990-present.

My Publications

Selected Publication

VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. Seu, KG; Trump, LR; Emberesh, S; Lorsbach, RB; Johnson, C; Meznarich, J; Underhill, HR; Chou, ST; Sakthivel, H; Nassar, NN; et al. American Journal of Human Genetics. 2020; 107:1149-1156.

Red cell membrane disorders: structure meets function. Risinger, M; Kalfa, TA. Blood. 2020; 136:1250-1261.

Signaling and cytoskeletal requirements in erythroblast enucleation. Konstantinidis, DG; Pushkaran, S; Johnson, JF; Cancelas, JA; Manganaris, S; Harris, CE; Williams, DA; Zheng, Y; Kalfa, TA. Blood. 2012; 119:6118-6127.

Implementation of near-universal hydroxyurea uptake among children with sickle cell anemia: A single-center experience. Karkoska, K; Todd, K; Niss, O; Clapp, K; Fenchel, L; Kalfa, TA; Malik, P; Quinn, CT; Ware, RE; McGann, PT. Pediatric Blood and Cancer. 2021; 68.

Automated Oxygen Gradient Ektacytometry: A Novel Biomarker in Sickle Cell Anemia. Sadaf, A; Seu, KG; Thaman, E; Fessler, R; Konstantinidis, DG; Bonar, HA; Korpik, J; Ware, RE; McGann, PT; Quinn, CT; et al. Frontiers in Physiology. 2021; 12.

Rasa3 regulates stage-specific cell cycle progression in murine erythropoiesis. Brindley, EC; Papoin, J; Kennedy, L; Robledo, RF; Ciciotte, SL; Kalfa, TA; Peters, LL; Blanc, L. Blood Cells, Molecules, and Diseases. 2021; 87.

Congenital dyserythropoietic anemia type I: First report from the Congenital Dyserythropoietic Anemia Registry of North America (CDAR). Niss, O; Lorsbach, RB; Berger, M; Chonat, S; McLemore, M; Buchbinder, D; McCavit, T; Shaffer, LG; Simpson, J; Schwartz, JH; et al. Blood Cells, Molecules, and Diseases. 2021; 87.

Altered erythropoiesis in newborns with congenital heart disease. Tseng, SY; Gao, Z; Kalfa, TA; Ollberding, NJ; Tabbah, S; Keller, R; Cnota, JF. Pediatric Research. 2021.

ER-to-Golgi transport and SEC23-dependent COPII vesicles regulate T cell alloimmunity. Kim, S; Khoriaty, R; Li, L; McClune, M; Kalfa, TA; Wu, J; Peltier, D; Fujiwara, H; Sun, Y; Oravecz-Wilson, K; et al. Journal of Clinical Investigation. 2021; 131.

Autoimmune Hemolytic Anemia in the Pediatric Setting. Voulgaridou, A; Kalfa, TA. Journal of Clinical Medicine. 2021; 10.