A photo of Theodosia A. Kalfa.

Theodosia A. Kalfa, MD, PhD

  • Co-Director, Erythrocyte Diagnostic Laboratory
  • Professor, UC Department of Pediatrics


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VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. Seu, KG; Trump, LR; Emberesh, S; Lorsbach, RB; Johnson, C; Meznarich, J; Underhill, HR; Chou, ST; Sakthivel, H; Nassar, NN; et al. American Journal of Human Genetics. 2020; 107:1149-1156.


Red cell membrane disorders: structure meets function. Risinger, M; Kalfa, TA. Blood. 2020; 136:1250-1261.


Signaling and cytoskeletal requirements in erythroblast enucleation. Konstantinidis, DG; Pushkaran, S; Johnson, JF; Cancelas, JA; Manganaris, S; Harris, CE; Williams, DA; Zheng, Y; Kalfa, TA. Blood. 2012; 119:6118-6127.

Diagnosis and clinical management of red cell membrane disorders. Kalfa, TA. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2021; 2021:331-340.

Characterizing bulk rigidity of rigid red blood cell populations in sickle-cell disease patients. Gutierrez, M; Shamoun, M; Seu, KG; Tanski, T; Kalfa, TA; Eniola-Adefeso, O. Scientific Reports. 2021; 11.

SERF1 Is Required for G-CSF Resistance of Start-Codon Mutant ELANE Granulocytic Precursors. Nayak, RC; Trump, L; Emberesh, S; Lee, Y; Singh, AK; Wellendorf, AM; Horwitz, MS; Kalfa, TA; Lutzko, C; Cancelas, JA. Blood. 2021; 138:433-433.

Overexpression of Human TLR8 Causes Fatal Anemia in SLE-Prone Mice By Altering the Bone Marrow Erythropoietic Niche. Davidson, A; Maria, N; Papoin, J; Raparia, C; Sun, Z; Zhang, W; Kalfa, TA; Paulson, R; Blanc, L. Blood. 2021; 138:1989-1989.

Activation of Pyruvate Kinase-R with Etavopivat (FT-4202) Is Well Tolerated, Improves Anemia, and Decreases Intravascular Hemolysis in Patients with Sickle Cell Disease Treated for up to 12 Weeks. Brown, RC C; Saraf, SL; Cruz, K; Idowu, M; Kalfa, TA; Geib, J; Forsyth, S; Schroeder, P; Wu, E; Kelly, P; et al. Blood. 2021; 138:9-9.

Etavopivat, an Allosteric Activator of Pyruvate Kinase-R, Improves Sickle RBC Functional Health and Survival and Reduces Systemic Markers of Inflammation and Hypercoagulability in Patients with Sickle Cell Disease: An Analysis of Exploratory Studies in a Phase 1 Study. Kalfa, TA; Telen, MJ; Saraf, SL; Brown, RC C; Giger Seu, K; Larkin, SK; Ribadeneira, MD; Schroeder, P; Wu, E; Kelly, P; et al. Blood. 2021; 138:8-8.

Trial in Progress: A Phase 2, Open-Label Study Evaluating the Safety and Efficacy of the PKR Activator Etavopivat (FT-4202) in Patients with Thalassemia or Sickle Cell Disease. Lal, A; Brown, RC C; Coates, TD; Kalfa, TA; Kwiatkowski, JL; Brevard, J; Potter, V; Wood, KW; Sheth, S. Blood. 2021; 138:4162-4162.

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