MD: Aristotle University Medical School, Thessaloniki, Greece, 1990.

PhD: Aristotle University Medical School, Thessaloniki, Greece, 1997.

Residency: University Of North Carolina, Chapel Hill, NC, 1999.

Fellowship: Duke University Medical Center, Durham, NC, 2003.

Certification: Hematology / oncology, American Board of Pediatrics, 2004; Pediatrics, American Board of Pediatrics, 2000; ECFMG Certification, 1995.

Licenses: Full and unrestricted medical license (OH Medical Board), 2003-present; full and unrestricted license of medical practice in Greece, 1990-present.

Services and Specialties

Cancer and Blood Diseases, Sickle Cell and Hemoglobin Disorders


Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species

Research Areas

Experimental Hematology and Cancer Biology, Hematology, Cancer and Blood Diseases

Additional Languages


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VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. Seu, KG; Trump, LR; Emberesh, S; Lorsbach, RB; Johnson, C; Meznarich, J; Underhill, HR; Chou, ST; Sakthivel, H; Nassar, NN; et al. The American Journal of Human Genetics. 2020; 107:1149-1156.


Red cell membrane disorders: structure meets function. Risinger, M; Kalfa, TA. Blood. 2020; 136:1250-1261.


Signaling and cytoskeletal requirements in erythroblast enucleation. Konstantinidis, DG; Pushkaran, S; Johnson, JF; Cancelas, JA; Manganaris, S; Harris, CE; Williams, DA; Zheng, Y; Kalfa, TA. Blood. 2012; 119:6118-6127.

Hemolytic anemia and macrothrombocytopenia: A lipid problem?. Risinger, M; Kim, PS; Rodriguez, RX; Narvaez Rivas, M; Setchell, KD R; Zhang, W; Kalfa, TA. American Journal of Hematology. 2023; 98:1335-1340.

Crosstalk between terminal erythropoiesis and granulopoiesis within their common niche: the erythromyeloblastic island. Romano, L; Seu, KG; Blanc, L; Kalfa, TA. Current Opinion in Hematology. 2023; 30:99-105.

Navigating the marrow sea towards erythromyeloblastic islands under normal and inflammatory conditions. Josselsohn, R; Barnes, BJ; Kalfa, TA; Blanc, L. Current Opinion in Hematology. 2023; 30:80-85.

Pediatric myelofibrosis due to compound heterozygous MPIG6B mutations in a patient of European ancestry. Yenwongfai, LN; Arora, R; Smith, AP; Kalfa, T; Husami, A; Radulescu, V; Myers, K; Lorsbach, R. Pediatric Blood and Cancer. 2023; 70:e30023.

Mutations in the RACGAP1 gene cause autosomal recessive congenital dyserythropoietic anemia type III. Hernández, G; Romero-Cortadellas, L; Ferrer-Cortès, X; Venturi, V; Dessy-Rodriguez, M; Olivella, M; Husami, A; de Soto, CP; Morales-Camacho, RM; Villegas, A; et al. Haematologica: the hematology journal. 2023; 108:581-587.

M-CSF supports medullary erythropoiesis and erythroid iron demand following burn injury through its activity on homeostatic iron recycling. Noel, JG; Ramser, SW; Pitstick, L; Bonamer, JP; Mackenzie, B; Seu, KG; Kalfa, TA; Cancelas, JA; Gardner, JC. Scientific Reports. 2022; 12:1235.

De Novo Germline DHX38 Variant Associated with Alternative Splicing of Multiple Transcripts in Iron-Related Pathways in a Patient with Atypical Congenital Dyserythropoietic Anemia with Ring Sideroblasts. Voulgaridou, A; Elgammal, Y; Husami, A; Emberesh, S; Seu, K; Ramamoorthy, M; Trump, L; Barasa, N; Nelson, AS; Lorsbach, RB; et al. Blood. 2022; 140:1234-1235.

From the Blog

Blood Cell Production Discovery Opens Path to Improve Anemia of Inflammation
Tools for Science

Blood Cell Production Discovery Opens Path to Improve Anemia of Inflammation

Theodosia A. Kalfa, MD, PhD10/31/2022

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