A photo of Benjamin Mizukawa.

Benjamin E. Mizukawa, MD


  • Research Director, Pediatric Cancer Avatar Program
  • Assistant Professor, UC Department of Pediatrics

About

MD: University of Utah, Salt Lake City, UT, 2004.

Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Certification: Pediatrics, 2008; Pediatric Hematology/Oncology, 2011.

Interests

Pediatric leukemia and lymphoma; investigation of the role of small Rho GTPases in leukemogenesis and leukemic stem cell biology and their potential as therapeutic targets in acute myeloid leukemia; development of xenograft models for use in testing novel therapeutics.

Services and Specialties

Cancer and Blood Diseases, Leukemia

Research Areas

Experimental Hematology and Cancer Biology, Oncology, Cancer and Blood Diseases

Insurance Information

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Publications

Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Nayak, RC; Chang, KH; Singh, AK; Kotliar, M; Desai, M; Wellendorf, AM; Wunderlich, M; Bartram, J; Mizukawa, B; Cuadrado, M; et al. Nature Communications. 2022; 13.

Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia. Hegde, S; Gasilina, A; Wunderlich, M; Lin, Y; Buchholzer, M; Krumbach, OH F; Akbarzadeh, M; Ahmadian, MR; Seibel, W; Zheng, Y; et al. Leukemia. 2022; 36:637-647.

Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms. Sabnis, HS; Shulman, DS; Mizukawa, B; Bouvier, N; Zehir, A; Fangusaro, J; Fabrizio, VA; Whitlow, C; Winchester, M; Agresta, L; et al. Journal of Clinical Oncology. 2021; 39:3822-3828.

Treatment of posttransplant lymphoproliferative disorder with poor prognostic features in children and young adults: Short-course EPOCH regimens are safe and effective. Rubinstein, JD; Shah, R; Breese, EH; Burns, KC; Mangino, JL; Norris, RE; Lee, L; Mizukawa, B; O'Brien, MM; Phillips, CL; et al. Pediatric Blood and Cancer. 2021; 68.

Hyperdiploid Precursor B-acute Lymphoblastic Leukemia Presenting as a Cavernous Sinus Mass in a 4-Year-old Male. Sabulski, A; Bartlett, AL; Koch, BL; Vatner, R; Mizukawa, B; Phillips, CL. Journal of Pediatric Hematology/Oncology. 2021; 43:e494-e497.

Hyperdiploid Precursor B-acute Lymphoblastic Leukemia Presenting as a Cavernous Sinus Mass in a 4-Year-old Male. Sabulski, A; Bartlett, AL; Koch, BL; Vatner, R; Mizukawa, B; Phillips, CL. Journal of Pediatric Hematology/Oncology. 2021; 43:e494-e497.

PD-1 Inhibition Enhances Blinatumomab Response in a UCB/PDX Model of Relapsed Pediatric B-Cell Acute Lymphoblastic Leukemia. Wunderlich, M; Manning, N; Sexton, C; O’Brien, E; Byerly, L; Stillwell, C; Perentesis, JP; Mulloy, JC; Mizukawa, B. Frontiers in Oncology. 2021; 11.

FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML. Sheng, Y; Yu, C; Liu, Y; Hu, C; Ma, R; Lu, X; Ji, P; Chen, J; Mizukawa, B; Huang, Y; et al. Nature Communications. 2020; 11.

Cyclosporine enhances the sensitivity to lenalidomide in MDS/AML in vitro. He, X; Dou, A; Feng, S; Roman-Rivera, A; Hawkins, C; Lawley, L; Zhang, J; Wunderlich, M; Mizukawa, B; Halene, S; et al. Experimental Hematology. 2020; 86:21-27.e2.

Methylation profiling of hypomethylating agent response and treatment failure in pediatric and young adult MDS/AML. Jones, LM; O'Brien, MM; Breese, EH; Absalon, M; Burns, KC; Grimley, M; Mizukawa, B; Lee, LH; Perentesis, JP; Phillips, CL. Journal of Clinical Oncology. 2020; 38:e22502-e22502.

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4.6
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