Francesco T. Mangano, DO, FACS, FAAP, FACOS
- Mary Jane and Bob Tritsch Chair, Division of Pediatric Neurosurgery
- Division Chief, Division of Pediatric Neurosurgery
- Director of the Pediatric Epilepsy Surgery Program, Division of Pediatric Neurosurgery
- Professor, UC Department of Neurosurgery
- Board Certified
About
Biography
I am currently the Mary Jane and Bob Tritsch Chair and professor of Neurological Surgery and Pediatrics. I joined the Division of Pediatric Neurosurgery at Cincinnati Children's in July 2005, with an appointment as assistant professor of neurosurgery in the College of Medicine at the University of Cincinnati.
I graduated from the Philadelphia College of Osteopathic Medicine and completed my neurosurgical residency at Long Island Jewish Medical Center in 2004, followed by a fellowship in pediatric neurosurgery at St. Louis Children's Hospital in St. Louis, Missouri. Since joining the faculty at Cincinnati Children's, I have been instrumental in developing our nationally renowned Pediatric Epilepsy Program and serve as the Director of the Pediatric Epilepsy Surgery Program.
In addition, I have been a co-principal investigator for an NIH-funded multi-institutional research study investigating advanced MRI imaging techniques in children with congenital hydrocephalus. This study established DTI as a non-invasive biomarker for white matter injury in this condition. I also head a basic science lab primarily focused on studying new models of hydrocephalus in combination with advanced MR imaging.
My academic endeavors have resulted in 111 publications and numerous book chapters. I have presented my work nationally and internationally and continue to teach locally as the site PI for pediatric neurosurgery residencies of the University of Cincinnati and the Henry Ford Medical Center.
I am also the fellowship director for the Cincinnati Children’s pediatric neurosurgery fellowship program, which has graduated 15 fellows and continues to recruit nationally every year. I am a member of the American Society of Pediatric Neurosurgeons, the AANS/CNS Section of Pediatric Neurosurgery, and the International Society of Pediatric Neurosurgery. I was board certified in 2008 in Neurological Surgery by the American Osteopathic Board of Surgery.
DO: Philadelphia College of Osteopathic Medicine, Philadelphia, PA.
Residency: Neurosurgery, NYCOM-Long Island Jewish Medical Center/North Shore University Hospital Health System, New Hyde Park, NY.
Fellowship: Pediatric Neurosurgery, Washington University School of Medicine-St. Louis Children's Hospital, St. Louis, MO.
Board Certification: Neurological Surgery, American Osteopathic Board of Surgery, 2008.
Interests
Pediatric Epilepsy Program; Pediatric Epilepsy Surgery Program; imaging and monitoring of seizures; surgical intervention; vagal nerve stimulator implantation; brain resection; brain and spinal cord tumors; chiari malformations; tethered cord syndromes in patients with anorectal malformations.
Services and Specialties
Interests
Advanced MRI imaging techniques in children with congenital hydrocephalus.
Research Areas
Additional Languages
Italian
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
Chronobiological Spatial Clusters of Cortical Regions in the Human Brain. Journal of Clinical Neurophysiology. 2025; 42:323-330.
User-defined virtual sensors: A new solution to the problem of temporal plus epilepsy sources. Epilepsia. 2025; 66:1071-1083.
Outcomes of Growth-Friendly Surgical Treatment of Early Onset Scoliosis in Children With Prune Belly Syndrome: A Preliminary Report. Journal of Pediatric Orthopaedics. 2025; 45:212-219.
Altered cortical excitability in tuberous sclerosis and the effect of mTOR inhibitors: An intracranial electrical stimulation study. Clinical Neurophysiology. 2025; 172:1-9.
A novel minimally invasive neurosurgical cranial fixation device for improved accuracy of intraventricular catheter placement: an experimental animal study. Patient Safety in Surgery. 2024; 18:36.
Antibiotic impregnated catheters and intrathecal antibiotics for CSF shunt infection prevention in children undergoing low-risk CSF shunt surgery. BMC Pediatrics. 2024; 24:325.
Infection rates during eras of intrathecal antibiotic use followed by antibiotic-impregnated catheter use in prevention of cerebrospinal fluid shunt infection. Journal of Neurosurgery: Pediatrics. 2024; 34:357-364.
High-gamma modulation language mapping and cognitive outcomes after epilepsy surgery. Epilepsia. 2024; 65:3052-3063.
White matter characteristics in children with cerebral palsy prior to selective dorsal rhizotomy: a multicenter diffusion tensor imaging study. Journal of Neurosurgery: Pediatrics. 2024; 34:268-277.
Impact of seizure onset zone and intracranial electroencephalography ictal characteristics on epilepsy surgery outcomes in tuberous sclerosis complex. Epilepsy Research. 2024; 205:107422.
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