BA: Duquesne University, Pittsburgh, PA.
MS: Clinical and Translational Research, University of Cincinnati, Cincinnati, OH.
MD: Medical College of Wisconsin, Milwaukee, WI.
Residency: Pediatrics, Medical College of Wisconsin/Children's Hospital of Wisconsin, Milwaukee, WI.
Fellowship: Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children's, Cincinnati, OH.
Certification: General Pediatrics; Pediatric Gastroenterology.
Pediatric inflammatory bowel disease; evidence-based care for children and young adults with IBD; sustained, prednisone-free clinical remission
Application of personalized medicine in the care of children and young adults with IBD through the discovery of surrogate biomarkers of intestinal inflammation; sensitive and specific pharmacodynamic biomarker, neutrophil CD64; innovative pharmacokinetic dosing platform, RoadMAB; personalized dosing of biologic therapies for patients with IBD; novel method to dose infliximab (guided by RoadMAB) from the start of treatment and throughout the maintenance phase to assess both the effectiveness and safety of model-informed precision dosing.
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Hybrid Population Pharmacokinetic-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn's Disease. Clinical Pharmacokinetics. 2025; 64:1669-1679.
Magnetic resonance imaging for suspected perianal Crohn's disease in children: a multi-reader agreement study. European Radiology. 2025; 35:5856-5863.
Acute pancreatitis gut dysbiosis persists at 1-year follow-up and is associated with clinical outcomes. Journal of Pediatric Gastroenterology and Nutrition. 2025; 81:690-698.
Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease: A Nationwide Survey of Anti-TNF Therapy Practices, Attitudes, and Barriers. Crohn's and Colitis 360. 2025; 7:otaf050.
Low Anti-Tumor Necrosis Factor Levels During Maintenance Phase Are Associated With Treatment Failure in Children With Crohn's Disease. Inflammatory Bowel Diseases. 2025; 31:1841-1850.
Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease. Inflammatory Bowel Diseases. 2025; 31:1380-1391.
HLA DQA1*05 and Risk of Antitumor Necrosis Factor Treatment Failure and Anti-Drug Antibody Development in Children With Crohn's Disease. The American Journal of Gastroenterology (Elsevier). 2025; 120:1076-1086.
Tu2094: COHORT FOR PEDIATRIC TRANSLATIONAL AND CLINICAL RESEARCH IN IBD (CAPTURE IBD): INITIAL ENROLLMENT OF A DIVERSE AND ADVANCED THERAPY-EXPOSED PROSPECTIVE COHORT. Gastroenterology. 2025; 169:s-1607.
36: LONGITUDINAL MICROBIAL SIGNATURES PREDICT DRUG CONCENTRATIONS, IMMUNOGENICITY, AND ENDOSCOPIC HEALING IN PEDIATRIC PATIENTS WITH CROHN’S DISEASE TREATED WITH ANTI-TNF THERAPY. Gastroenterology. 2025; 169:s-13-s-14.
Editorial: Baseline Drug Clearance Predicts Outcomes in Children With Inflammatory Bowel Disease Treated With Vedolizumab. Alimentary Pharmacology and Therapeutics. 2025; 61:1063-1064.
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