Similarity regression predicts evolution of transcription factor sequence specificity.
Lambert, SA; Yang, AW H; Sasse, A; Cowley, G; Albu, M; Caddick, MX; Morris, QD; Weirauch, MT; Hughes, TR.
Nature Genetics.
2019;
51:981-989.
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity.
Harley, JB; Chen, X; Pujato, M; Miller, D; Maddox, A; Forney, C; Magnusen, AF; Lynch, A; Chetal, K; Yukawa, M; et al.
Nature Genetics.
2018;
50:699-707.
The Human Transcription Factors.
Lambert, SA; Jolma, A; Campitelli, LF; Das, PK; Yin, Y; Albu, M; Chen, X; Taipale, J; Hughes, TR; Weirauch, MT.
Cell.
2018;
172:650-665.
Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.
Zhang, G; Feenstra, B; Bacelis, J; Liu, X; Muglia, LM; Juodakis, J; Miller, DE; Litterman, N; Jiang, P; Russell, L; et al.
The New England journal of medicine.
2017;
377:1156-1167.
Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning.
Alipanahi, B; Delong, A; Weirauch, MT; Frey, BJ.
Nature Biotechnology.
2015;
33:831-838.
Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity.
Weirauch, MT; Yang, A; Albu, M; Cote, AG; Montenegro-Montero, A; Drewe, P; Najafabadi, HS; Lambert, SA; Mann, I; Cook, K; et al.
Cell.
2014;
158:1431-1443.
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.
Kottyan, LC; Davis, BP; Sherrill, JD; Liu, K; Rochman, M; Kaufman, K; Weirauch, MT; Vaughn, S; Lazaro, S; Rupert, AM; et al.
Nature Genetics.
2014;
46:895-900.
A compendium of RNA-binding motifs for decoding gene regulation.
Ray, D; Kazan, H; Cook, KB; Weirauch, MT; Najafabadi, HS; Li, X; Gueroussov, S; Albu, M; Zheng, H; Yang, A; et al.
Nature.
2013;
499:172-177.
Evaluation of methods for modeling transcription factor sequence specificity.
Weirauch, MT; Cote, A; Norel, R; Annala, M; Zhao, Y; Riley, TR; Saez-Rodriguez, J; Cokelaer, T; Vedenko, A; Talukder, S; et al.
Nature Biotechnology.
2013;
31:126-134.
Conserved expression without conserved regulatory sequence: the more things change, the more they stay the same.
Weirauch, MT; Hughes, TR.
Trends in Genetics.
2010;
26:66-74.