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A photo of Stavra Xanthakos.

Director, Steatohepatitis Center

Medical Director, Surgical Weight Loss Program for Teens

Associate Director, Gastroenterology Fellowship Program

Associate Professor, UC Department of Pediatrics

513-636-4415

513-636-7805

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My Biography & Research

Biography

Stavra A. Xanthakos, MD, is an attending physician in the Division of Gastroenterology, Hepatology and Nutrition, the co-director of the Cincinnati Children’s Steatohepatitis Center, and the medical director of the Surgical Weight Loss Program for Teens. She is an assistant professor for the University of Cincinnati College of Medicine. She also partners with physicians and staff in Cincinnati Children’s Center for Better Health and Nutrition in the evaluation and management of pediatric patients suffering from severe pediatric obesity and related complications.

Dr. Xanthakos received her medical degree from Duke University in 1997 and a Master of Science degree in molecular epidemiology from the University of Cincinnati in 2006. Her post-doctoral training, including residency, chief residency and fellowship were completed at Cincinnati Children's and she joined the faculty within the University of Cincinnati College of Medicine in 2005. During her fellowship, Dr. Xanthakos investigated the prevalence and outcome of non-alcoholic fatty liver disease (NAFLD) in young adult women as her master’s thesis in molecular epidemiology. Her current clinical and translational research is focused on identify the predictors and outcome of obesity-related liver disease (nonalcoholic fatty liver disease and steatohepatitis), in obese adolescents undergoing bariatric surgery. She is also a co-investigator in the NIH sponsored Teen LABS, a multicenter consortium investigating bariatric surgery in adolescents and in the NIH-sponsored NASH Clinical Research Network. Additional research interests of Dr. Xanthakos include the treatment and prevention of pediatric obesity, outcomes of bariatric surgery in adolescents, malnutrition in pediatric obesity, as well as identifying genetic and environmental risk factors for pediatric nonalcoholic fatty liver disease to enable better evaluation and treatment options. She also leads clinical quality improvement initiatives in the Steatohepatitis Center, which are aligned with divisional and institutional initiatives to achieve measurable improvements in children’s health and disease outcomes.

Dr. Xanthakos has published extensively in the field of pediatric obesity, bariatric medicine and non-alcoholic fatty liver disease. She regularly is invited to speak about pediatric obesity evaluation and management, particularly bariatric medicine, and pediatric nonalcoholic fatty liver disease.

Additional Languages

German, Greek

Clinical Interests

Non-alcoholic fatty liver disease and steatohepatitis; pediatric obesity; bariatric surgery; nutrition

Research Interests

Prevalence, determinants and outcome of pediatric obesity-related liver disease (Non-alcoholic fatty liver disease and steatohepatitis); bariatric medicine; pediatric obesity and nutrition

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Divisions

Gastroenterology GI, Steatohepatitis, Surgical Weight Loss, Autoimmune Liver Disease, Gastroenterology

Science Blog

Many Teens Have Low Iron, B12 Levels Years After Bariatric Surgery

Diabetes and Obesity

Many Teens Have Low Iron, B12 Levels Years After Bariatric Surgery

Stavra A. Xanthakos, MD, MS11/8/2019

Bariatric Surgery Improves Outcomes for Obese Teens

Diabetes and Obesity

Bariatric Surgery Improves Outcomes for Obese Teens

Stavra A. Xanthakos, MD, MS6/28/2019

My Locations

My Education

MD: Duke University, Durham, NC, 1997.

MS: Molecular Epidemiology, University of Cincinnati, 2006.

Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1997-2000.

Chief Residency: Cincinnati Children's, Cincinnati, OH, 2000-01.

Clinical Fellowship: Gastroenterology, Hepatology & Nutrition, Cincinnati Children's, Cincinnati, OH, 2001-2004.

Research Fellowship: Molecular Epidemiology in Children's Environmental Health, Masters of Science, 2002-2005.

Certification: Pediatrics, 2008; Pediatric Gastroenterology, 2005.

My Publications

Selected Publication

Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. Inge, TH; Courcoulas, AP; Jenkins, TM; Michalsky, MP; Brandt, ML; Xanthakos, SA; Dixon, JB; Harmon, CM; Chen, MK; Xie, C; et al. The New England journal of medicine. 2019; 380:2136-2145.

Assessment of Nonalcoholic Fatty Liver Disease Progression in Children Using Magnetic Resonance Imaging. Mouzaki, M; Trout, AT; Arce-Clachar, AC; Bramlage, K; Kuhnell, P; Dillman, JR; Xanthakos, S. The Journal of Pediatrics. 2018; 201:86-92.

Added Sugars and Cardiovascular Disease Risk in Children: A Scientific Statement From the American Heart Association. Vos, MB; Kaar, JL; Welsh, JA; Van Horn, LV; Feig, DI; Anderson, CA M; Patel, MJ; Cruz Munos, J; Krebs, NF; Xanthakos, SA; et al. Circulation. 2017; 135:e1017-e1034.

NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). Vos, MB; Abrams, SH; Barlow, SE; Caprio, S; Daniels, SR; Kohli, R; Mouzaki, M; Sathya, P; Schwimmer, JB; Sundaram, SS; et al. Journal of Pediatric Gastroenterology and Nutrition. 2017; 64:319-334.

In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores. Schwimmer, JB; Lavine, JE; Wilson, LA; Neuschwander-Tetri, BA; Xanthakos, SA; Kohli, R; Barlow, SE; Vos, MB; Karpen, SJ; Molleston, JP; et al. Gastroenterology. 2016; 151:1141-1154.e9.

Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. Newton, KP; Hou, J; Crimmins, NA; Lavine, JE; Barlow, SE; Xanthakos, SA; Africa, J; Behling, C; Donithan, M; Clark, JM; et al. JAMA Pediatrics. 2016; 170:e161971-e161971.

Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. Inge, TH; Courcoulas, AP; Jenkins, TM; Michalsky, MP; Helmrath, MA; Brandt, ML; Harmon, CM; Zeller, MH; Chen, MK; Xanthakos, SA; et al. The New England journal of medicine. 2016; 374:113-123.

High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery. Xanthakos, SA; Jenkins, TM; Kleiner, DE; Boyce, TW; Mourya, R; Karns, R; Brandt, ML; Harmon, CM; Helmrath, MA; Michalsky, MP; et al. Gastroenterology. 2015; 149:623e8-634.e8.

Baseline BMI is a Strong Predictor of Nadir BMI after Adolescent Gastric Bypass. Inge, TH; Jenkins, TM; Zeller, M; Dolan, L; Daniels, SR; Garcia, VF; Brandt, ML; Bean, J; Gamm, K; Xanthakos, SA. The Journal of Pediatrics. 2010; 156:103-108 e1-U148.

Vitamin D deficiency: prevalence and association with liver disease severity in pediatric nonalcoholic fatty liver disease. Yodoshi, T; Orkin, S; Arce-Clachar, AC; Bramlage, K; Liu, C; Fei, L; El-Khider, F; Dasarathy, S; Xanthakos, SA; Mouzaki, M. European Journal of Clinical Nutrition. 2020; 74:427-435.