Hope Steele
Fort Wayne, IN
Research focus: Tumor necrosis factor superfamily (TNFSF) member control of airway inflammation and fibrosis.
Why did you choose UC? The partnership with Cincinnati Children’s Hospital allows the research to have incredible translational potential, with opportunities for physician collaborations and access to cutting-edge technologies.
Why study Immunology? The study of immunology is vast and key to our understanding of almost any disease, with immense clinical relevance. It is essential for us to understand the intricacies of the immune system in order to develop novel therapeutics and innovative treatment strategies for human disease.
Awards or publications: Publication ORCID ID Number: 0000-0001-9107-5742
Steele H, Sachen K, McKnight AJ, Soloff R, Herro R. Targeting TL1A/DR3 Signaling Offers a Therapeutic Advantage to Neutralizing IL13/IL4Rα in Muco-Secretory Fibrotic Disorders. Front Immunol. 2021 Jul 8;12:692127. doi: 10.3389/fimmu.2021.692127. PMID: 34305924; PMCID: PMC8299868.
Steele H, Song B, Willicut A, Grimes HL, Herro R. Isolation of primary immune cells from fibrotic skin, esophageal, and gut tissue. J Immunol Methods. 2021 Aug 2;497:113107. doi: 10.1016/j.jim.2021.113107. Epub ahead of print. PMID: 34352237.