The patient may have a procedure, called a wide resection with margins, to remove the tumor and some tissue around the tumor. If the doctor is concerned that the cancer has also spread to nearby lymph nodes, they may also be removed.
Patients may have radiation treatment before surgery to make the tumor smaller. After surgery, additional radiation therapy can help kill any tumor cells left in the body.
The doctor will make a plan for radiation based on the treatment goals and the location of the tumor.
Two types of radiation are used, regular radiation or proton radiation. Proton radiation has less side effects because it kills the tumor but does not hurt organs and healthy tissue. Cincinnati Children’s is one of the few pediatric hospitals in the country that offers proton therapy.
If the tumor is large or has spread to other areas, the doctor may recommend chemotherapy or other types of drugs to help kill the cancer cells.
Clinical Research Trials
Epithelioid sarcoma can be challenging to treat. In some situations, the doctor may recommend participating in a clinical trial at Cincinnati Children's. Researchers − including those at Cincinnati Children’s − are testing experimental therapies that target the SMARCB1 genetic mutation that is associated with epithelioid sarcoma and other tumor types.
Follow-up imaging tests can help monitor how the cancer is responding to treatment.