Clinical Rationale/Problem Solved
Medication-associated AKI is underrecognized, causes a lot of morbidity, and is a costly safety issue
Potential Impact
We have shown dramatic improvements in both risk and injury, cutting both by >65-70%.
DSAW Investigators
Eric Kirkendall
Collaborators
Stuart Goldstein (PI), Katie Walsh, Steve Muething
Grants
"AHRQ R18 Grant #5R18HS023763 (Peer-reviewed)
“NINJA2: Reduction of Nephrotoxic Medication-associated Acute Kidney Injury in Children”
Principal Investigator: Stuart Goldstein, MD
Casey Lee Ball Foundation extramural grant
“Reduction of Nephrotoxic Medication Associated Acute Kidney Injury in Children”
Principal Investigator: Stuart Goldstein, MD
Role: Co-investigator
Role: Co-investigator
Agency for Healthcare Research and Quality Grant #U19HS021114 (Peer-reviewed)
“Pursuing Perfection In Pediatric Therapeutics”
Principal Investigator: Carole Lannon, MD"
Publications
Goldstein SL, Mottes T, Simpson K, Barclay C, Muething S, Haslam DB, Kirkendall ES. A sustained quality improvement program reduces nephrotoxic medication-associated acute kidney injury. Kidney Int. 2016 Jul;90(1):212-21.
Menon S, Kirkendall ES, Nguyen H, Goldstein SL. Acute kidney injury associated with high nephrotoxic medication exposure leads to chronic kidney disease after 6 months. J Pediatr. 2014 Sep;165(3):522-7.e2.
Kirkendall ES, Spires WL, Mottes TA, Schaffzin JK, Barclay C, Goldstein SL. Development and performance of electronic acute kidney injury triggers to identify pediatric patients at risk for nephrotoxic medication-associated harm. Appl Clin Inform. 2014 Apr 2;5(2):313-33.
Goldstein SL, Kirkendall E, Nguyen H, Schaffzin JK, Bucuvalas J, Bracke T, Seid M, Ashby M, Foertmeyer N, Brunner L, Lesko A, Barclay C, Lannon C, Muething S. Electronic health record identification of nephrotoxin exposure and associated acute kidney injury. Pediatrics. 2013 Sep;132(3):e756-67.