Pulmonary Biology

Faculty Labs

Our lab investigates how normal lung development is regulated—and how these processes are disrupted in disease—by studying intercellular signaling and gene control using advanced genetic, genomic, and imaging approaches.

Our lab investigates pediatric vascular malformations and tumors to uncover disease mechanisms, identify diagnostic and prognostic biomarkers, and develop safer, targeted therapies through collaborative research.

Our lab defines the cellular and molecular networks driving lung repair and regeneration, using advanced multiomic and imaging tools and clinical partnerships to translate discoveries into therapies for pulmonary disease.

Our lab studies how fibroblasts regulate lung development, injury, and regeneration, with a focus on transcriptional and signaling networks that drive bronchopulmonary dysplasia and lung repair.

Our lab investigates epithelial–mesenchymal interactions and signaling pathways that pattern the developing respiratory tract, using advanced mouse models and live imaging to understand normal lung formation and congenital disease.

Our lab studies lung development and disease by using transgenic mouse models, gene targeting, and molecular approaches to uncover mechanisms of epithelial differentiation, surfactant regulation, and respiratory disorders.

Our lab uses bioinformatics, multi-omics, and single-cell analysis to map lung development and disease, uncover regulatory mechanisms, and identify origins and therapeutic targets for disorders like LAM.

Our lab investigates how cellular metabolism directs cell fate decisions and migration during embryonic development to understand mechanisms underlying tissue formation and birth defects.