Le Cras Lab
Publications

Publications

McDaniel, CG; Adams, DM; Steele, KE; Hammill, AM; Merrow, AC; Crane, JL; Smith, CL; Kozakewich, HP W; Le Cras, TD. Kaposiform lymphangiomatosis: Diagnosis, pathogenesis, and treatment. Pediatric Blood and Cancer. 2023; 70:e30219.

Boscolo, E; Pastura, P; Schrenk, S; Goines, J; Kang, R; Pillis, D; Malik, P; Le Cras, TD. NRASQ61R mutation in human endothelial cells causes vascular malformations. Angiogenesis. 2022; 25:331-342.

Henry, BM; de Oliveira, MH S; Cheruiyot, I; Benoit, JL; Cooper, DS; Lippi, G; Le Cras, TD; Benoit, SW. Circulating level of Angiopoietin-2 is associated with acute kidney injury in coronavirus disease 2019 (COVID-19). Angiogenesis. 2021; 24:403-406.

Crane, J; Manfredo, J; Boscolo, E; Coyan, M; Takemoto, C; Itkin, M; Adams, DM; Le Cras, TD. Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood angiopoietin-2 levels. Pediatric Blood and Cancer. 2020; 67:e28529.

Le Cras, TD; Goines, J; Lakes, N; Pastura, P; Hammill, AM; Adams, DM; Boscolo, E. Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation. Angiogenesis. 2020; 23:425-442.

Le Cras, TD; Adams, DM. Comment on: Potential biomarkers of kaposiform lymphangiomatosis. Pediatric Blood and Cancer. 2020; 67:e28100.

Le Cras, TD; Abman, SH. Early Disruption of VEGF Receptor Signaling and the Risk for Adult Emphysema. American Journal of Respiratory and Critical Care Medicine. 2020; 201:620-621.

Boscolo, E; Pastura, P; Glaser, K; Goines, J; Hammill, AM; Adams, DM; Dickie, P; Dickie, BH; Le Cras, TD. Signaling pathways and inhibitors of cells from patients with kaposiform lymphangiomatosis. Pediatric Blood and Cancer. 2019; 66:e27790.

Le Cras, TD; Boscolo, E. Cellular and molecular mechanisms of PIK3CA-related vascular anomalies. Vascular Biology. 2019; 1:H33-H40.

Li, X; Cai, Y; Goines, J; Pastura, P; Brichta, L; Lane, A; Le Cras, TD; Boscolo, E. Ponatinib Combined With Rapamycin Causes Regression of Murine Venous Malformation. Arteriosclerosis, Thrombosis, and Vascular Biology. 2019; 39:496-512.