Publications

Boscolo, E; Pastura, P; Schrenk, S; Goines, J; Kang, R; Pillis, D; Malik, P; Le Cras, TD. NRASQ61R mutation in human endothelial cells causes vascular malformations. Angiogenesis. 2022.

Engel, E; Ricci, K; Hammill, AM; Mittermeier, K; LeCras, TD; Luchtman-Jones, L. Use of Serum Antiopoietin-2 Assay for Therapeutic Decision-Making in Patients with Vascular Anomalies. Blood. 2021; 138:4929-4929.

Henry, BM; de Oliveira, MH S; Cheruiyot, I; Benoit, JL; Cooper, DS; Lippi, G; Le Cras, TD; Benoit, SW. Circulating level of Angiopoietin-2 is associated with acute kidney injury in coronavirus disease 2019 (COVID-19). Angiogenesis. 2021; 24:403-406.

Crane, J; Manfredo, J; Boscolo, E; Coyan, M; Takemoto, C; Itkin, M; Adams, DM; Le Cras, TD. Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood angiopoietin-2 levels. Pediatric Blood and Cancer. 2020; 67.

Le Cras, TD; Goines, J; Lakes, N; Pastura, P; Hammill, AM; Adams, DM; Boscolo, E. Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation. Angiogenesis. 2020; 23:425-442.

Le Cras, TD; Adams, DM. Comment on: Potential biomarkers of kaposiform lymphangiomatosis. Pediatric Blood and Cancer. 2020; 67.

Le Cras, TD; Abman, SH. Early Disruption of VEGF Receptor Signaling and the Risk for Adult Emphysema. American Journal of Respiratory and Critical Care Medicine. 2020; 201:620-621.

Boscolo, E; Pastura, P; Glaser, K; Goines, J; Hammill, AM; Adams, DM; Dickie, P; Dickie, BH; Le Cras, TD. Signaling pathways and inhibitors of cells from patients with kaposiform lymphangiomatosis. Pediatric Blood and Cancer. 2019; 66.

Le Cras, TD; Boscolo, E. Cellular and molecular mechanisms of PIK3CA-related vascular anomalies. 2019; 1:H33-H40.

Li, X; Cai, Y; Goines, J; Pastura, P; Brichta, L; Lane, A; Le Cras, TD; Boscolo, E. Ponatinib Combined With Rapamycin Causes Regression of Murine Venous Malformation. Arteriosclerosis, Thrombosis, and Vascular Biology. 2019; 39:496-512.

Ikeda, KT; Hale, PT; Pauciulo, MW; Dasgupta, N; Pastura, PA; Le Cras, TD; Pandey, MK; Nichols, WC. Hypoxia-induced Pulmonary Hypertension in Different Mouse Strains: Relation to Transcriptome. American Journal of Respiratory Cell and Molecular Biology. 2019; 60:106-116.

Wang, KC W; Le Cras, TD; Larcombe, AN; Zosky, GR; Elliot, JG; James, AL; Noble, PB. Independent and combined effects of airway remodelling and allergy on airway responsiveness. Clinical Science. 2018; 132:327-338.