Who can participate?
Teens and young adults 14 to 25 years old who:
- Have been diagnosed on the autism spectrum
- Have failed one or more evidence-based antidepressant treatments (e.g. an SSRI, talk therapy like CBT)
What will happen in the study?
This study includes 15 study visits at Cincinnati Children’s over about 16 weeks. There are 3 phases in the study. Here are some of the things that will happen in this study.
If you qualify, you will be randomly assigned (like flipping a coin) to one of two treatment groups (both receiving active rTMS treatment for 2 weeks).
During the first screening phase of 2 weeks, you will:
- Go through the consent process with a research coordinator. *
- Fill out questionnaires. *
- Complete a cognitive assessment.
- Undergo EEG testing with eye-tracking.
- Submit a urine drug screen.
- Be given a Mood Foundations brochure with tips about managing depression.
In the second phase or intervention phase of 2 weeks, you/your child will:
- Receive half-day TMS treatment 5 days a week (M-F) for 2 weeks.
- On days 5 and 10 of the intervention, complete additional questionnaires and an EEG.
In the third phase or follow-up phase, you will attend visits 1, 4, and 12 weeks after your final TMS treatment, and in each one you will be asked to complete a set of questionnaires*, an EEG, physiological measures, and a cognitive assessment.
* Denotes things that can be done remotely
Will you/your child be paid to be in this research study?
Participants will receive up to $1000 for participation in this study.