The Diagnostic Center for Heritable Immunodeficiencies (DCHI) at Cincinnati Children’s is the largest and most specialized center in North America for the diagnosis of rare primary immunodeficiencies, bone marrow failure syndromes and other disorders of the immune system. The DCHI has been recognized as a center of excellence by the Federation of Clinical Immunology Societies and the Jeffrey Modell Foundation.
Introducing: Immunology Exome
Our Immunology Exome utilizes Whole Exome Sequencing (WES) technology but focuses on a predefined list of 351 genes that are associated with immune system defects or related disorders. Genes associated with susceptibility to recurrent or unusual infections, antibody deficiencies, immune dysregulation, malignancy, allergy, autoimmunity, and auto-inflammatory disorders are included in our comprehensive analysis of heritable immune system defects and disorders.
Immunology Exome | Test Requisition
Next-generation sequencing (NGS) panels
Other disorders for which the DCHI offers rapid screening and genetic diagnostic testing include Wiskott-Aldrich syndrome (WAS), X-linked lymphoproliferative disease (XLP) and X-linked immune dysregulation, polyendocrinopathy enteropathy syndrome (IPEX).
> Visit our HLH Center of Excellence pages for more information about the treatment of hemophagocytic lymphohistiocytosis.