Currently, Cincinnati Children’s is conducting many research studies that could change the face of diagnosis and care for HLH. The physician scientists of our HLH Center focus on innovative basic and translational research with the ultimate goal of improving curative treatments for HLH. Some of our innovative work includes:

  • Development of an HLH gene chip
  • Preclinical studies of gene therapy in PRF1 deficiency

While we already have strong collaborations with the National Institutes of Health (NIH) and other HLH centers around the globe including China, Japan, Vietnam, Canada and Sweden, we plan to further extend our scientific collaborations to new centers worldwide.

We are also working to increase research funding for HLH through industry grants, additional NIH funding and philanthropic support.

Published Research

> Read some of our HLH research articles from