MD: UT Southwestern, Dallas, TX, 1993.

Residency: Children's Hospital of Dallas, Dallas, TX, 1996.

Fellowship: The Children's Hospital, Denver, CO, 2002.

Certification: American Board of Pediatrics, 1996; Sub-board of Pediatric Heme/Onc, 2002.


Histiocytic disorders: HLH and LCH

Services and Specialties

Cancer and Blood Diseases, Immune Deficiencies and Histiocytosis, Bone Marrow Transplantation BMT, Leukemia, Hemophagocytic lymphohistiocytosisHLH, Histiocytosis Center, Autoimmune Liver Disease, Rare Lung Diseases


Better understanding histiocytic disorders and developing novel therapies for them; regulation of the immune response; immunotherapy of cancer

Research Areas

Bone Marrow Transplantation and Immune Deficiency, Cancer and Blood Diseases, Immunobiology

Insurance Information

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Prospective two center study of CD38 bright CD8+ effector memory T-cells as a predictor of acute GVHD. Khandelwal, P; Chaturvedi, V; Owsley, E; Efebera, YA; Choe, H; Bostic, M; Kumchala, P; Rajgolikar, G; Ranganathan, P; Garzon, R; et al. Transplantation Reports. 2022; 7:100100.

Quercetin ameliorates XIAP deficiency-associated hyperinflammation. Chiang, SC C; Owsley, E; Panchal, N; Chaturvedi, V; Terrell, CE; Jordan, MB; Mehta, PA; Davies, SM; Akeno, N; Booth, C; et al. Blood. 2022; 140:706-715.

HLH: birds of a feather flock together. Jordan, MB. Blood. 2022; 140:167-168.

P1203: THE OPTIMIZED HLH INFLAMMATORY (OHI) INDEX IDENTIFIES LYMPHOMA PATIENTS WITH UNEXPECTEDLY HIGH MORTALITY NOT RELATED TO DISEASE PROGRESSION. Zoref-Lorenz, A; Murakami, J; Hofstetter, L; Abadi, U; Iyer, S; Mohamed, S; Miller, PG; Natour, AE H; Weinstein, S; Yacobovich, J; et al. HemaSphere. 2022; 6:1089-1090.

Emapalumab in primary haemophagocytic lymphohistiocytosis and the pathogenic role of interferon gamma: A pharmacometric model-based approach. Jacqmin, P; Laveille, C; Snoeck, E; Jordan, MB; Locatelli, F; Ballabio, M; de Min, C. British Journal of Clinical Pharmacology. 2022; 88:2128-2139.

Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults. Hines, MR; Von Bahr Greenwood, T; Beutel, G; Beutel, K; Hays, JA; Horne, A; Janka, G; Jordan, MB; Van Laar, JA M; Lachmann, G; et al. Critical Care Medicine. 2022; 50:860-872.

A Case of Chronic Lymphocytic Leukemia Complicated by Hemophagocytic Lymphohistiocytosis: Identifying the Aberrant Immune Response. Zoref-Lorenz, A; Yuklea, M; Topaz, G; Jordan, MB; Ellis, M. Journal of General Internal Medicine. 2022; 37:1542-1546.

Malignancy-associated haemophagocytic lymphohistiocytosis. Setiadi, A; Zoref-Lorenz, A; Lee, CY; Jordan, MB; Chen, LY C. The Lancet Haematology. 2022; 9:e217-e227.

An improved index for diagnosis and mortality prediction in malignancy-associated hemophagocytic lymphohistiocytosis. Zoref-Lorenz, A; Murakami, J; Hofstetter, L; Iyer, S; Alotaibi, AS; Mohamed, SF; Miller, PG; Guber, E; Weinstein, S; Yacobovich, J; et al. Blood. 2022; 139:1098-1110.

High risk of relapsed disease in patients with NK/T-cell chronic active Epstein-Barr virus disease outside of Asia. Davila Saldana, BJ; John, T; Bonifant, C; Buchbinder, D; Chandra, S; Chandrakasan, S; Chang, W; Chen, L; Elfassy, HL; Geerlinks, AV; et al. Blood Advances. 2022; 6:452-459.

From the Blog

NEJM: Emapalumab Clinical Trial Shows Positive Results Against HLH
Rare Diseases

NEJM: Emapalumab Clinical Trial Shows Positive Results Against HLH

Michael B. Jordan, MD5/7/2020

Breakthrough Therapy Improves Life for Children with LRBA Deficiency
Rare Diseases

Breakthrough Therapy Improves Life for Children with LRBA Deficiency

Michael B. Jordan, MD6/28/2019

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