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Prospective two center study of CD38 bright CD8+ effector memory T-cells as a predictor of acute GVHD. Khandelwal, P; Chaturvedi, V; Owsley, E; Efebera, YA; Choe, H; Bostic, M; Kumchala, P; Rajgolikar, G; Ranganathan, P; Garzon, R; et al. Transplantation Reports. 2022; 7.

Quercetin ameliorates XIAP deficiency-associated hyperinflammation. Chiang, SC C; Owsley, E; Panchal, N; Chaturvedi, V; Terrell, CE; Jordan, MB; Mehta, PA; Davies, SM; Akeno, N; Booth, C; et al. Blood. 2022; 140:706-715.

HLH: birds of a feather flock together. Jordan, MB. Blood. 2022; 140:167-168.

P1203: THE OPTIMIZED HLH INFLAMMATORY (OHI) INDEX IDENTIFIES LYMPHOMA PATIENTS WITH UNEXPECTEDLY HIGH MORTALITY NOT RELATED TO DISEASE PROGRESSION. Zoref-Lorenz, A; Murakami, J; Hofstetter, L; Abadi, U; Iyer, S; Mohamed, S; Miller, PG; Natour, AE H; Weinstein, S; Yacobovich, J; et al. HemaSphere. 2022; 6:1089-1090.

Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults. Hines, MR; Von Bahr Greenwood, T; Beutel, G; Beutel, K; Hays, JA; Horne, A; Janka, G; Jordan, MB; Van Laar, JA M; Lachmann, G; et al. Critical Care Medicine. 2022; 50:860-872.

Emapalumab in primary haemophagocytic lymphohistiocytosis and the pathogenic role of interferon gamma: A pharmacometric model-based approach. Jacqmin, P; Laveille, C; Snoeck, E; Jordan, MB; Locatelli, F; Ballabio, M; de Min, C. British Journal of Clinical Pharmacology. 2022; 88:2128-2139.

A Case of Chronic Lymphocytic Leukemia Complicated by Hemophagocytic Lymphohistiocytosis: Identifying the Aberrant Immune Response. Zoref-Lorenz, A; Yuklea, M; Topaz, G; Jordan, MB; Ellis, M. Journal of General Internal Medicine. 2022; 37:1542-1546.

Malignancy-associated haemophagocytic lymphohistiocytosis. Setiadi, A; Zoref-Lorenz, A; Lee, CY; Jordan, MB; Chen, LY C. The Lancet Haematology. 2022; 9:e217-e227.

An improved index for diagnosis and mortality prediction in malignancy-associated hemophagocytic lymphohistiocytosis. Zoref-Lorenz, A; Murakami, J; Hofstetter, L; Iyer, S; Alotaibi, AS; Mohamed, SF; Miller, PG; Guber, E; Weinstein, S; Yacobovich, J; et al. Blood. 2022; 139:1098-1110.

High risk of relapsed disease in patients with NK/T-cell chronic active Epstein-Barr virus disease outside of Asia. Davila Saldana, BJ; John, T; Bonifant, C; Buchbinder, D; Chandra, S; Chandrakasan, S; Chang, W; Chen, L; Elfassy, HL; Geerlinks, AV; et al. Blood Advances. 2022; 6:452-459.

From the Blog

NEJM: Emapalumab Clinical Trial Shows Positive Results Against HLH
Rare Diseases

NEJM: Emapalumab Clinical Trial Shows Positive Results Against HLH

Michael B. Jordan, MD5/7/2020

Breakthrough Therapy Improves Life for Children with LRBA Deficiency
Rare Diseases

Breakthrough Therapy Improves Life for Children with LRBA Deficiency

Michael B. Jordan, MD6/28/2019

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