About
MD: Nagoya University, Nagoya, Japan, 2003,
PhD: Tokyo University, Tokyo, Japan, 2008,
Residency: Pediatrics, Columbia University, New York, NY,
Fellowship: Pediatric Gastroenterology, Northwestern University, Chicago, IL,
Fellowship: Advanced/Transplant Hepatology, University of Cincinnati, Cincinnati, OH,
Certifications: Pediatrics, 2010; Pediatric Gastroenterology, Hepatology and Nutrition, 2013; Advanced/Transplant Hepatology
Interests
Pediatric hepatology; pediatric transplant hepatology
Interests
Pediatric hepatology; genetic and molecular mechanism of liver development and pathophysiology
Additional Languages
Japanese
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
The Outcome of Patients With Cystic Biliary Atresia With Intact Proximal Hepatic Ducts Following Hepatic-Cyst-Jejunostomy. Journal of Pediatric Gastroenterology and Nutrition. 2022; 75(2):131-137.
Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency. JHEP Reports. 2022; 4(4):100446.
Biliary Atresia and Other Disorders of the Extrahepatic Bile Ducts. In: Liver Disease in Children. Cambridge University Press (CUP); 2021:162-181.
Modeling Human Bile Acid Transport and Synthesis in Stem Cell-Derived Hepatocytes with a Patient-Specific Mutation. Stem Cell Reports. 2021; 16(2):309-323.
Pathogenesis of biliary atresia: defining biology to understand clinical phenotypes. Nature Reviews Gastroenterology and Hepatology. 2015; 12(6):342-352.
Baseline analysis of patient reported outcomes in the progressive familial intrahepatic cholestasis patient registry. Journal of Pediatric Gastroenterology and Nutrition. 2026.
68 Structural and Functional Development of the Hepatobiliary System. In: Pediatric Gastrointestinal and Liver Disease. Elsevier; 2026:809-817.e3.
Pharmacokinetic Monitoring of JAK Inhibitor and Tacrolimus for Safe and Effective Management of Graft-Versus-Host Disease After Pediatric Liver Transplantation. Pediatric Transplantation. 2025; 29(7):e70187.
Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells. Cellular and Molecular Gastroenterology and Hepatology (CMGH). 2025; 19(4):101444.
Structural and Functional Development of the Hepatobiliary System. In: Pediatric Gastrointestinal and Liver Disease. 2025:809-817.e3.
From the Blog
Cincinnati Children’s Launches Research Center for Rare Liver Diseases
Akihiro Asai, MD, PhD, William F. Balistreri, MD ...12/6/2021
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