Akihiro Asai, MD, PhD

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-803-1791

Email akihiro.asai@cchmc.org

Clinical

Pediatric hepatology; pediatric transplant hepatology

Research

Pediatric hepatology; genetic and molecular mechanism of liver development and pathophysiology

MD: Nagoya University, Nagoya, Japan, 2003.

PhD: Tokyo University, Tokyo, Japan, 2008.

Residency: Pediatrics, Columbia University, New York, NY.

Certification: Pediatrics, 2010.

Fellowship: Pediatric Gastroenterology, Hepatology and Nutrition, Northwestern University, Chicago, IL.

Certification: Pediatric Gastroenterology, Hepatology and Nutrition, 2013.

Fellowship: Advanced/Transplant Hepatology, University of Cincinnati, Cincinnati, OH.

Certification: Advanced/Transplant Hepatology.

View PubMed Publications

Asai A, Kohli R. Familial homozygous hypercholesterolemia: When to turn to transplant? Pediatric Transplantation. 2015;19: 577–579.

Asai A, Miethke A, Bezerra J. Pathogenesis of biliary atresia: defining biology to understand clinical phenotypes. Nat Rev Gastroenterol Hepatol. 2015 Jun;12(6):342-352.

Asai A, Malladi S, Misch J, Pan X, Malladi P, Diehl AM, Whitington PF. Elaboration of tubules with active Hedgehog drives parenchymal fibro genesis in gestational alloimmune liver disease. Human Pathology. 2015 Jan;46(1):84-93.

Asai A, Chou PM, Bu HF, Wang X, Rao MS, Jiang A, DiDonato CJ, Tan XD. Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice. Am J Physiol Gastrointest Liver Physiol. 2014 Mar;306(6):G496-504.

Wang X, Bu HF, Zhong W, Asai A, Zhou Z, Tan XD. MFG-E8 and HMGB1 are involved in the mechanism underlying alcohol-induced impairment of macrophage engulfing apoptotic cells. Mol Med. 2013 Jul 24;19:170-82.

Asai A, Sahani N, Kaneki M, Ouchi Y, Martyn JJ, Yasuhara S. Primary Role of Functional Ischemia, Quantitative Evidence of Two-Hit Mechanism, and Phosphodiesterase-5 Inhibitor Therapy in Mouse Muscular Dystrophy. PLoS One. 2007 Aug 29;2(8):e806.

Asai A, Sahani N, Ouchi Y, Martyn JJ, Yasuhara S. In vivo Micro-circulation Measurement in Skeletal Muscle by Intra-vital Microscopy. J Vis Exp. 2007;(4):210.