A photo of Akihiro Asai.

Assistant Professor, UC Department of Pediatrics


Board Certified

My Biography & Research

Additional Languages


Clinical Interests

Pediatric hepatology; pediatric transplant hepatology

Research Interests

Pediatric hepatology; genetic and molecular mechanism of liver development and pathophysiology

Academic Affiliation

Assistant Professor, UC Department of Pediatrics

Clinical Divisions

Gastroenterology GI, Liver Transplant, Autoimmune Liver Disease, Liver Care, Liver Tumor

Research Divisions

Gastroenterology Hepatology and Nutrition

My Locations

My Education

MD: Nagoya University, Nagoya, Japan, 2003.

PhD: Tokyo University, Tokyo, Japan, 2008.

Residency: Pediatrics, Columbia University, New York, NY.

Certification: Pediatrics, 2010.

Fellowship: Pediatric Gastroenterology, Hepatology and Nutrition, Northwestern University, Chicago, IL.

Certification: Pediatric Gastroenterology, Hepatology and Nutrition, 2013.

Fellowship: Advanced/Transplant Hepatology, University of Cincinnati, Cincinnati, OH.

Certification: Advanced/Transplant Hepatology.

My Publications

Biliary Atresia and Other Disorders of the Extrahepatic Bile Ducts. Bezerra, JA; Asai, A; Tiao, G; Mullapudi, B; Balistreri, WF. Liver Disease in Children. 2021.

Acute liver dysfunction with delayed peak of serum aminotransferase levels as a presentation of ornithine transcarbamylase deficiency in females. Clarkston, K; Lee, J; Donoghue, S; Peters, H; Eiroa, H; Shah, AA; Loomes, K; Wen, J; Oliver, M; Hardikar, W; et al. American Journal of Medical Genetics, Part A. 2021; 185:909-915.

Modeling Human Bile Acid Transport and Synthesis in Stem Cell-Derived Hepatocytes with a Patient-Specific Mutation. Hayashi, H; Osaka, S; Sakabe, K; Fukami, A; Kishimoto, E; Aihara, E; Sabu, Y; Mizutani, A; Kusuhara, H; Naritaka, N; et al. Stem Cell Reports. 2021; 16:309-323.

High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. Shinozawa, T; Kimura, M; Cai, Y; Saiki, N; Yoneyama, Y; Ouchi, R; Koike, H; Maezawa, M; Zhang, RR; Dunn, A; et al. Gastroenterology. 2021; 160:831-846.e10.

Organoid Medicine in Hepatology. Sakabe, K; Takebe, T; Asai, A. Clinical Liver Disease. 2020; 15:3-8.

Prospective Assessment of Ultrasound Shear Wave Elastography for Discriminating Biliary Atresia from other Causes of Neonatal Cholestasis. Dillman, JR; DiPaola, FW; Smith, SJ; Barth, RA; Asai, A; Lam, S; Campbell, KM; Bezerra, JA; Tiao, GM; Trout, AT. Journal of Pediatrics. 2019; 212:60-65.e3.

50 Years Ago in The Journal of Pediatrics: Diagnosis of Biliary Atresia: Relative Accuracy of Percutaneous Liver Biopsy, Open Liver Biopsy, and Operative Cholangiography. Asai, A. Journal of Pediatrics. 2017; 189.

Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells. Asai, A; Aihara, E; Watson, C; Mourya, R; Mizuochi, T; Shivakumar, P; Phelan, K; Mayhew, C; Helmrath, M; Takebe, T; et al. Development (Cambridge). 2017; 144:1056-1064.