A photo of Theresa Alenghat.

Member, Division of Immunobiology

Associate Professor, UC Department of Pediatrics


Biography & Affiliation

Academic Affiliation

Associate Professor, UC Department of Pediatrics


Immunobiology, Inflammation and Tolerance

Science Blog


BS: Brown University, Providence, RI, 1999.

VMD: University of Pennsylvania, Philadelphia, PA, 2003.

PhD: University of Pennsylvania, Philadelphia, PA, 2007.

Residency: Anatomic Pathology, University of Pennsylvania, Philadelphia, PA.

Certification: Diplomate ACVP, 2011.


Selected Publication

Microbiota Inhibit Epithelial Pathogen Adherence by Epigenetically Regulating C-Type Lectin Expression. Woo, V; Eshleman, EM; Rice, T; Whitt, J; Vallance, BA; Alenghat, T. Frontiers in Immunology. 2019; 10.

Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. Kelly, D; Kotliar, M; Woo, V; Jagannathan, S; Whitt, J; Moncivaiz, J; Aronow, BJ; Dubinsky, MC; Hyams, JS; Markowitz, JF; et al. JCI insight. 2018; 3.

Disruption of Epithelial HDAC3 in Intestine Prevents Diet-Induced Obesity in Mice. Whitt, J; Woo, V; Lee, P; Moncivaiz, J; Haberman, Y; Denson, L; Tso, P; Alenghat, T. Gastroenterology. 2018; 155:501-513.

Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. Jiang, TT; Shao, T; Ang, WX G; Kinder, JM; Turner, LH; Pham, G; Whitt, J; Alenghat, T; Way, SS. Cell Host and Microbe. 2017; 22:809-816.e4.

Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation. Navabi, N; Whitt, J; Wu, S; Woo, V; Moncivaiz, J; Jordan, MB; Vallance, BA; Way, SS; Alenghat, T. Cell Reports. 2017; 19:1165-1175.

Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection. Gray, J; Oehrle, K; Worthen, G; Alenghat, T; Whitsett, J; Deshmukh, H. Science Translational Medicine. 2017; 9:eaaf9412-eaaf9412.

Host-microbiota interactions: epigenomic regulation. Woo, V; Alenghat, T. Current Opinion in Immunology. 2017; 44:52-60.

Respiratory epithelial cells orchestrate pulmonary innate immunity. Whitsett, JA; Alenghat, T. Nature Immunology. 2015; 16:27-35.

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis. Alenghat, T; Osborne, LC; Saenz, SA; Kobuley, D; Ziegler, CG K; Mullican, SE; Choi, I; Grunberg, S; Sinha, R; Wynosky-Dolfi, M; et al. Nature. 2013; 504:153-157.

Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria. Sonnenberg, GF; Monticelli, LA; Alenghat, T; Fung, TC; Hutnick, NA; Kunisawa, J; Shibata, N; Grunberg, S; Sinha, R; Zahm, AM; et al. Science. 2012; 336:1321-1325.