A photo of Theresa Alenghat.

Member, Division of Immunobiology

Associate Professor, UC Department of Pediatrics

513-803-7498

Biography & Affiliation

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Divisions

Immunobiology, Inflammation and Tolerance



Blog Posts

Tissue Healing in the Gut Depends on Help from Friendly Bacteria

Digestive System

Tissue Healing in the Gut Depends on Help from Friendly Bacteria

Theresa Alenghat, VMD, PhD7/30/2020

Our 2019 Research Annual Report

Genomics and Development

Our 2019 Research Annual Report

Theresa Alenghat, VMD, PhD, John Hogenesch, PhD ...2/4/2020

Emerging Pathway for Predicting the Severity of Crohn’s Disease

Digestive System

Emerging Pathway for Predicting the Severity of Crohn’s Disease

Theresa Alenghat, VMD, PhD7/1/2019

Education

BS: Brown University, Providence, RI, 1999.

VMD: University of Pennsylvania, Philadelphia, PA, 2003.

PhD: University of Pennsylvania, Philadelphia, PA, 2007.

Residency: Anatomic Pathology, University of Pennsylvania, Philadelphia, PA.

Certification: Diplomate ACVP, 2011.

Publications

Selected Publication

Insulin-like Growth Factor 1 Supports a Pulmonary Niche that Promotes Type 3 Innate Lymphoid Cell Development in Newborn Lungs. Oherle, K; Acker, E; Bonfield, M; Wang, T; Gray, J; Lang, I; Bridges, J; Lewkowich, I; Xu, Y; Ahlfeld, S; et al. Immunity. 2020; 52:275-294.e9.

Microbiota Inhibit Epithelial Pathogen Adherence by Epigenetically Regulating C-Type Lectin Expression. Woo, V; Eshleman, EM; Rice, T; Whitt, J; Vallance, BA; Alenghat, T. Frontiers in Immunology. 2019; 10.

Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. Kelly, D; Kotliar, M; Woo, V; Jagannathan, S; Whitt, J; Moncivaiz, J; Aronow, BJ; Dubinsky, MC; Hyams, JS; Markowitz, JF; et al. JCI insight. 2018; 3.

Disruption of Epithelial HDAC3 in Intestine Prevents Diet-Induced Obesity in Mice. Whitt, J; Woo, V; Lee, P; Moncivaiz, J; Haberman, Y; Denson, L; Tso, P; Alenghat, T. Gastroenterology. 2018; 155:501-513.

Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. Jiang, TT; Shao, T; Ang, WX G; Kinder, JM; Turner, LH; Pham, G; Whitt, J; Alenghat, T; Way, SS. Cell Host and Microbe. 2017; 22:809-816.e4.

Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation. Navabi, N; Whitt, J; Wu, S; Woo, V; Moncivaiz, J; Jordan, MB; Vallance, BA; Way, SS; Alenghat, T. Cell Reports. 2017; 19:1165-1175.

Host-microbiota interactions: epigenomic regulation. Woo, V; Alenghat, T. Current Opinion in Immunology. 2017; 44:52-60.

Respiratory epithelial cells orchestrate pulmonary innate immunity. Whitsett, JA; Alenghat, T. Nature Immunology. 2015; 16:27-35.

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis. Alenghat, T; Osborne, LC; Saenz, SA; Kobuley, D; Ziegler, CG K; Mullican, SE; Choi, I; Grunberg, S; Sinha, R; Wynosky-Dolfi, M; et al. Nature. 2013; 504:153-157.

Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria. Sonnenberg, GF; Monticelli, LA; Alenghat, T; Fung, TC; Hutnick, NA; Kunisawa, J; Shibata, N; Grunberg, S; Sinha, R; Zahm, AM; et al. Science. 2012; 336:1321-1325.