A photo of Sing Sing Way.

Pauline and Lawson Reed Chair, Division of Infectious Diseases

Associate Professor, UC Department of Pediatrics


Board Certified

My Biography & Research


Dr. Way is an infectious disease physician-scientist. He cares for infants and children with infection related illness, and provides consultation in the diagnosis and prevention diseases caused by communicable agents. Dr. Way supervises an active basic research laboratory that uses basic immunological approaches to investigate ways to boost host defense and protection against infection. Ongoing projects investigate the immune basis responsible for enhanced susceptibility to infection during pregnancy, the immune pathogenesis of pregnancy complications that occur with maternal infection, and the basic signals required for stimulating immune cell activation.

Dr. Way trained in the combined MD/PhD program at the Albert Einstein College of Medicine, pediatric residency at the University of California San Francisco, and infectious disease fellowship at the University of Washington. During fellowship training, Dr. Way began investigating the basic immunology and immune pathogenesis of infectious diseases relevant to human, and in particular, infant and child health.

Dr. Way’s research has been supported by the National Institutes of Health since 2006. Dr. Way’s research has been described in many publications in numerous prestigious scientific journals including Nature, Cell Host & Microbe, PLoS Pathogens, and The Journal of Immunology. The past and ongoing work has also been recognized by numerous prestigious awards including the Infectious Diseases Society of America Wyeth Young Investigator Award, a Basil O’ Conner Award from the March of Dimes Foundation, and the Investigator in Pathogenesis of Infectious Diseases award from the Burroughs Wellcome Fund. 

Academic Affiliation

Associate Professor, UC Department of Pediatrics


Infectious Diseases, Infectious Diseases, Prevention of Preterm Birth, Inflammation and Tolerance

Science Blog

Immune System Works Differently Between and First and Later Pregnancies

Infectious Diseases and Vaccines

Immune System Works Differently Between and First and Later Pregnancies

Sing Sing Way, MD, PhD6/23/2020

Vaccine Strategies to Protect More Newborns from Fatal Infections

Infectious Diseases and Vaccines

Vaccine Strategies to Protect More Newborns from Fatal Infections

Sing Sing Way, MD, PhD5/7/2020

My Education

MD PhD: Albert Einstein College of Medicine, Bronx, NY, 1999.

Residency: University of California San Francisco, San Francisco, CA, 2001.

Fellowship: University of Washington, Seattle, WA, 2004.

My Publications

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. Kotov, DI; Mitchell, JS; Pengo, T; Ruedl, C; Way, SS; Langlois, RA; Fife, BT; Jenkins, MK. Journal of immunology (Baltimore, Md. : 1950). 2019; 202:2535-2545.

Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. Shao, T; Ang, WX G; Jiang, TT; Huang, FS; Andersen, H; Kinder, JM; Pham, G; Burg, AR; Ruff, B; Gonzalez, T; et al. Cell Host and Microbe. 2019; 25:404-417.e6.

Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications. Deshmukh, H; Way, SS. Annual Review of Pathology: Mechanisms of Disease. 2019; 14:185-210.

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. DiToro, D; Winstead, CJ; Pham, D; Witte, S; Andargachew, R; Singer, JR; Wilson, CG; Zindl, CL; Luther, RJ; Silberger, DJ; et al. Science. 2018; 361:eaao2933-eaao2933.

Declining responsiveness to influenza vaccination with progression of human pregnancy. Schlaudecker, EP; Ambroggio, L; McNeal, MM; Finkelman, FD; Way, SS. Vaccine. 2018; 36:4734-4741.

A disconnect between precursor frequency, expansion potential, and site-specific CD4(+) T cell responses in aged mice. Deshpande, NR; Uhrlaub, JL; Way, SS; Nikolich-Zugich, J; Kuhns, MS. PLoS ONE. 2018; 13:e0198354-e0198354.

Mycobacterium tuberculosis-specific CD4(+) and CD8(+) T cells differ in their capacity to recognize infected macrophages. Yang, JD; Mott, D; Sutiwisesak, R; Lu, Y; Raso, F; Stowell, B; Babunovic, GH; Lee, J; Carpenter, SM; Way, SS; et al. PLoS Pathogens. 2018; 14:e1007060-e1007060.

Immunology of the Uterine and Vaginal Mucosae. Zhou, JZ; Way, SS; Chen, K. Trends in Immunology. 2018; 39:302-314.

Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. Jiang, TT; Shao, T; Ang, WX G; Kinder, JM; Turner, LH; Pham, G; Whitt, J; Alenghat, T; Way, SS. Cell Host and Microbe. 2017; 22:809-816.e4.

Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. Turner, LH; Kinder, JM; Wilburn, A; D'Mello, RJ; Braunlin, MR; Jiang, TT; Pham, G; Way, SS. PLoS Pathogens. 2017; 13:e1006684-e1006684.