A photo of Stefanie Benoit.

Medical Director, Nephrology Clinical Lab

Assistant Professor, UC Department of Pediatrics

513-636-8647

Board Certified

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"I was inspired by the potentially dramatic effects of decreasing kidney injury rates, and I dedicated the next three years of my life to a fellowship in pediatric nephrology, with a research and clinical focus in pediatric onco-nephrology."

My Biography & Research

Biography

As a pediatric nephrologist, I treat children and adolescents with hypertension, acute kidney injury and chronic kidney disease. I also care for patients who are on acute or chronic dialysis, and I have a special interest in pediatric onco-nephrology. In my practice, I strive to have honest and collaborative relationships with my patients.

I was drawn to my specialty area as a bone marrow transplant hospitalist, where I witnessed acute kidney injury increase the risk of therapy-related toxicity and limit participation in clinical trials. Acute kidney injury also necessitated treatment changes that jeopardized the patient’s chances for cure. I was inspired by the potentially dramatic effects of decreasing kidney injury rates, and I dedicated the next three years of my life to a fellowship in pediatric nephrology, with a research and clinical focus in pediatric onco-nephrology.

In addition to seeing patients, I’m involved in research. My long-term research objective is to improve renal outcomes for children receiving oncology therapies. The ultimate goal of my research is to improve the likelihood that pediatric cancer and immunodeficiency patients can achieve successful cures of their disease without kidney injury or long-term kidney complications.

I was honored to be named one of Cincinnati’s Top Doctors in 2020, by Cincinnati Magazine. I have been awarded three University of Cincinnati College of Medicine Optime Magistrum (Best Teacher) Awards, and I have $100,000 in University of Cincinnati Cancer Institute Cancer Survivorship Pilot Research Grants.

In my spare time, I enjoy playing the cello and ukulele. I also love to spend time with my two awesome kids and go jogging outdoors with my husband.

Academic Affiliation

Assistant Professor, UC Department of Pediatrics

Clinical Divisions

Nephrology and Hypertension

Research Divisions

Nephrology and Hypertension, Bone Marrow Transplantation and Immune Deficiency

My Locations

My Education

MPH: Case Western Reserve University School of Medicine, 2007.

MD: Case Western Reserve University School of Medicine, 2010.

MA: Bioethics, Case Western Reserve University School of Medicine, 2010.

Residency: Cincinnati Children's Hospital Medical Center, 2013.

Certification: Pediatrics, 2014.

My Publications

Selected Publication

Complement blockade for TA-TMA: lessons learned from a large pediatric cohort treated with eculizumab. Jodele, S; Dandoy, CE; Lane, A; Laskin, BL; Laskin, B; Teusink-Cross, A; Myers, KC; Wallace, G; Nelson, AS; Nelson, A; et al. Blood. 2020; 135:1049-1057.

A novel strategy for identifying early acute kidney injury in pediatric hematopoietic stem cell transplantation. Benoit, SW; Dixon, BP; Goldstein, SL; Bennett, MR; Lane, A; Lounder, DT; Rotz, SJ; Gloude, NJ; Lake, KE; Litts, B; et al. Bone Marrow Transplantation. 2019; 54:1453-1461.

Reduction in Nephrotoxic Antimicrobial Exposure Decreases Associated Acute Kidney Injury in Pediatric Hematopoietic Stem Cell Transplant Patients. Benoit, SW; Goldstein, SL; Dahale, DS; Haslam, DB; Nelson, A; Truono, K; Davies, SM. Biology of Blood and Marrow Transplantation. 2019; 25:1654-1658.

Acute kidney injury: emerging pharmacotherapies in current clinical trials. Benoit, SW; Devarajan, P. Pediatric Nephrology. 2018; 33:779-787.

Circulating Levels of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Are Independent Predictors of Coronavirus Disease 2019 Severity: A Prospective, Observational Study. Henry, BM; Cheruiyot, I; Benoit, JL; Lippi, G; Prohászka, Z; Favaloro, EJ; Benoit, SW. Seminars in Thrombosis and Hemostasis. 2021; 47:451-455.

Alterations in the lipid profile associate with a dysregulated inflammatory, prothrombotic, anti-fibrinolytic state and development of severe acute kidney injury in coronavirus disease 2019 (COVID-19): A study from Cincinnati, USA. Henry, BM; Szergyuk, I; de Oliveira, MH S; Abosamak, MF; Benoit, SW; Benoit, JL; Lippi, G. Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 2021; 15:863-868.

Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. Azouz, NP; Klingler, AM; Callahan, V; Akhrymuk, IV; Elez, K; Raich, L; Henry, BM; Benoit, JL; Benoit, SW; Noé, F; et al. Pathogens and Immunity. 2021; 6:55-74.

Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study. Henry, BM; Cheruiyot, I; Benoit, SW; Sanchis-Gomar, F; Lippi, G; Benoit, J. Molecular pathology : MP. 2021.

Circulating level of Angiopoietin-2 is associated with acute kidney injury in coronavirus disease 2019 (COVID-19). Henry, BM; de Oliveira, MH S; Cheruiyot, I; Benoit, JL; Cooper, DS; Lippi, G; Le Cras, TD; Benoit, SW. Angiogenesis. 2021.

Tolerance of dinutuximab therapy for treatment of high-risk neuroblastoma in two patients with end-stage renal disease on dialysis. Emberesh, M; Rubinstein, JD; Young, J; Benoit, SW; Dandoy, CE; Weiss, BD. Pediatric Blood and Cancer. 2021; 68.