My pursuit of a career in medicine was inspired early in life by my father and many wonderful teachers. My specific interest in cardiac transplantation care and research developed while a fellow at Stanford University. There, I was fortunate to be guided by heart transplant pioneer, Dr. Norman Shumway.
The guidance and mentorship I received by the man considered to be the father of heart transplantation has led me to a rewarding clinical and research career.
At Cincinnati Children’s, I serve as director of Advanced Cardiomyopathy Services and medical director of Pediatric Heart Transplant. My clinical work is focused on transplant rejection, coronary artery disease and cardiopulmonary exercise testing. These clinical interests have become research interests as well. Another focus of my research in cardiac transplantation includes the detection, prevention and modification of antibodies against human leukocyte antigens.
I’m particularly interested in better understanding allograft vasculopathy, a leading cause of morbidity and mortality in cardiac transplantation. In pediatrics, especially, allograft vasculopathy is difficult to detect, prevent and treat.
MD: SUNY Downstate Medical Center, Brooklyn, NY, 1989.
Residency: Pediatrics, University of California Davis Medical Center, Sacramento, CA, 1989.
Fellowship: Stanford University, Stanford, CA, 1992.
Pediatric cardiology; cardiomyopathy and transplantation
Cardiomyopathy, Heart Failure, Heart, Cardio-Oncology, Neuromuscular Disorders
Cardiomyopathy and transplantation
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Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association. Arteriosclerosis, Thrombosis, and Vascular Biology. 2019; 39:e38-e81.
Early initiation of mTOR inhibitors in children with heart transplantation: A propensity-based registry analysis. Journal of Heart and Lung Transplantation. 2016; 35:253-255.
Outcomes after percutaneous coronary artery revascularization procedures for cardiac allograft vasculopathy in pediatric heart transplant recipients: A multi-institutional study. Journal of Heart and Lung Transplantation. 2015; 34:1163-1168.
Improved Detection of Cardiac Allograft Vasculopathy: A Multi-Institutional Analysis of Functional Parameters in Pediatric Heart Transplant Recipients. Journal of the American College of Cardiology. 2015; 66:547-557.
Supine cycling in pediatric exercise testing: disparity in performance measures. Pediatric Cardiology. 2014; 35:705-710.
Donors' characteristics and impact on outcomes in pediatric heart transplant recipients. Pediatric Transplantation. 2013; 17:774-781.
Early predictors of survival to and after heart transplantation in children with dilated cardiomyopathy. Circulation. 2012; 126:1079-1086.
Supine exercise echocardiographic measures of systolic and diastolic function in children. Journal of the American Society of Echocardiography. 2012; 25:773-781.
Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients. Journal of Heart and Lung Transplantation. 2011; 30:158-163.
Correlation of subjective questionnaires with cardiac function as determined by exercise testing in a pediatric population. Pediatric Cardiology. 2010; 31:1043-1048.