I was influenced by my father, who was a pediatrician and took great satisfaction in caring for children. As a pediatric infectious disease specialist, I work with my patients and their families as a team and feel that taking care of children is a wonderful privilege and a responsibility.
In my practice, I try to be flexible by coordinating my patients’ appointments with those of other providers when possible. I’m committed to providing continuity and to being accessible between visits.
I’m the director of the Antimicrobial Stewardship Program and the Microbial Genomics and Metagenomics Laboratory. I've received several teaching and research awards, including the Pediatric Infectious Disease Society Young Investigator Award.
The main focus of my research is on the microbiome, which is the community of bacteria, viruses, fungi and other organisms that live on the human body. The goal is to understand how the microbiome influences disease and contributes to health in children. A healthy microbiome helps protect against infection, allergy, gastrointestinal diseases, heart disease, diabetes and diseases of premature infants.
In my free time, I enjoy riding my bike.
MD: University of Calgary, Calgary, Alberta.
Rotating Internship: McGill University, Montreal, Quebec.
Residency: University of Ottawa, Ottawa, Quebec.
Fellowship: Washington University School of Medicine, St. Louis, MO.
Infectious Diseases, Autoimmune Liver Disease
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Intestinal permeability in patients undergoing stem cell transplantation correlates with systemic acute phase responses and dysbiosis. Blood Advances. 2023; 7:5137-5151.
The microbiome in adolescents with irritable bowel syndrome and changes with percutaneous electrical nerve field stimulation. Neurogastroenterology and Motility. 2023; 35:e14573.
Analysis of the fecal metagenome in long-term survivors of pancreas cancer. Cancer. 2023; 129:1986-1994.
Airway transcriptome networks identify susceptibility to frequent asthma exacerbations in children. Journal of Allergy and Clinical Immunology. 2023; 152:73-83.
Benchmarking of Outpatient Pediatric Antibiotic Prescribing: Results of a Multicenter Collaborative. Journal of the Pediatric Infectious Diseases Society. 2023; 12:364-371.
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation. The Journal of Experimental Medicine. 2023; 220:e20212523.
Delayed Microbial Maturation Durably Exacerbates Th17-driven Asthma in Mice. American Journal of Respiratory Cell and Molecular Biology. 2023; 68:498-510.
Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance. Alimentary Pharmacology and Therapeutics. 2023; 57:524-539.
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity. The Journal of Clinical Investigation. 2023; 133:e162190.
A New Algorithm Identifying Association of Staphylococcus aureus Strains with Low Expression of Filaggrin in Atopic Dermatitis. Journal of Allergy and Clinical Immunology. 2023; 151:ab146.
David B. Haslam, MD, Theresa Alenghat, VMD, PhD ...2/15/2023