A photo of David Haslam.

Director, Antimicrobial Stewardship Program

Director, Microbial Genomics and Metagenomics Laboratory

Associate Professor, UC Department of Pediatrics

513-803-1170

My Biography & Research

Biography

David Haslam, MD, is an associate professor in the Division of Infectious Diseases at Cincinnati Children’s Hospital Medical Center within the UC Department of Pediatrics serving both as an Infectious Diseases specialist and a clinical and translational researcher. He is the director of the Microbial Genomics and Metagenomics Laboratory and the Antimicrobial Stewardship Program at Cincinnati Children’s.

The laboratory’s main focus is on the microbiome; the community of bacteria, viruses, fungi, and other organisms that live on the human body. Recently, it has become clear that the microbiome has very important contributions to human health and disease. A healthy microbiome helps protect against infection, allergy, gastrointestinal diseases, heart disease, diabetes, and diseases of premature infants.

Dr. Haslam’s research focus is to understand relationships between the microbiome and childhood health. The laboratory’s major focus has been to understand the relationships between antibiotic exposure, altered microbial ecology, and risk for subsequent infection; particularly with antibiotic-resistant bacteria. His laboratory has developed collaborations with many others at the University of Cincinnati and Cincinnati Children’s Hospital to study the microbiome in health and disease.

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Departments

Infectious Diseases, Infectious Diseases, Autoimmune Liver Disease

My Locations

My Education

MD: University of Calgary, Calgary, Alberta.

Rotating Internship: McGill University, Montreal, Quebec.

Residency: University of Ottawa, Ottawa, Quebec.

Fellowship: Washington University School of Medicine, St. Louis, MO.

My Publications

Brower LH, Wilson PM, Kurowski EM, Haslam D, Courter J, Goyal N, Durling M, Shah SS, Schondelmeyer A. Using quality improvement to implement a standardized approach to neonatal herpes simplex virus. Pediatrics. 2019.

Tchou MJ, Andersen H, Robinette E, Mortensen JE, Powell EA, Ankrum A, Washam MC, Haslam DM, Courter JD. Reducing time to use of adequate antimicrobial agents in a children’s hospital using real-time decision support and PCR with microarray testing. Pediatric Quality and Safety. 2019.

Scaggs Huang FA, Mortensen J, Skoch J, Andersen H, Staat MA, Schaffzin JK, Haslam DB. Successful whole genome sequencing-guided treatment of Mycoplasma hominis ventriculitis in a preterm infant. Pediatr Infect Dis J. 2019 Jul;38(7):749-751.

Benoit SW, Goldstein SL, Dehale DS, Haslam DB, Nelson A, Truono K, Davies SM. Reduction in nephrotoxic antimicrobial exposure decreases associated acute kidney injury in pediatric hematopoietic stem cell transplant patients. Biol Blood Marrow Transplant. 2019.

Shao TY, Ang WXG, Jiang TT, Huang FS, Andersen H, Kinder JM, Pham G, Burg AR, Ruff B, Gonzalez T, Khurana Hershey GK, Haslam DB, Way SS. Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. Cell Host Microbe. 2019;25(3):404-417 e406.

Liu R, Moriggl R, Zhang D, Li H, Karns R, Ruan HB, Niu H, Mayhew C, Watson C, Bangar H, Cha SW, Haslam D, Zhang T, Gilbert S, Li N, Helmrath M, Wells J, Denson L, Han X. Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis. Life Sci Alliance. 2019;2(2).

Wang JC, Bergeron M, Andersen H, Tikhtman R, Haslam D, Hunter T, Herr AB, de Alarcon A. Feasibility of shotgun metagenomics to assess microbial ecology of pediatric tracheostomy tubes. Laryngoscope. 2019;129(2):317-323.

Khandelwal P, Andersen H, Romick-Rosendale L, Taggart CB, Watanabe M, Lane A, Dandoy CE, Lake KE, Litts BA, Morrow AL, Lee ML, Haslam DB, Davies SM. A Pilot Study of Human Milk to Reduce Intestinal Inflammation After Bone Marrow Transplant. Breastfeed Med. 2019;14(3):193-202.

Forster CS, Powell EA, DeBurger B, Courter J, Haslam DB, Mortensen JE. Association of systemic antimicrobials with the expression of beta-lactamases in bacteria cultured from urological patients. Diagn Microbiol Infect Dis. 2019;10(18):30718-30711.

Washam MC, Ankrum A, Haberman BE, Staat MA, Haslam DB. Risk Factors for Staphylococcus aureus Acquisition in the Neonatal Intensive Care Unit: A Matched Case-Case-Control Study. Infect Control Hosp Epidemiol. 2018;39(1):46-52.