A photo of Thomas D. Ryan.

Director of Clinical Operations, Cardiomyopathy and Advanced Heart Failure

Co-Director, Cardio-Oncology Program

Associate Professor, UC Department of Pediatrics


Board Certified

About Me


Thomas D. Ryan, MD, PhD, was born and raised in Wichita, KS and graduated magna cum laude from Wichita State University in 1996 with a BS in biological sciences.

In 1997 he began training in the MD/PhD program at the University of Alabama at Birmingham, and studied the molecular, cellular, and whole organ aspects of cardiac remodeling in a rat model of volume overload. His general pediatrics residency training took place at Cincinnati Children’s Hospital Medical Center from 2006-2009, as did his pediatric cardiology fellowship training from 2009-2012 and advanced fellowship in Pediatric Heart Failure/Transplant from 2012-2013. His clinical and research interests focus on heart failure, cardiomyopathy, cardiac transplantation and mechanical circulatory support. He focuses on patients who have developed heart dysfunction as a result of cancer-related therapies.

He is on the Leadership Council of the Cardio-oncology Member Section of the American College of Cardiology and has authored peer-reviewed manuscripts, reviews and textbook chapters on pediatric cardio-oncology.

Clinical Interests

Cardiomyopathy; cardio-oncology; heart transplant; mechanical circulatory support

Research Interests

Cardiomyopathy; cardio-oncology; heart transplant

Academic Affiliation

Associate Professor, UC Department of Pediatrics


Neuromuscular Disorders, Cardiomyopathy, Heart Failure, Rasopathy, Cardio-Oncology, Heart, Neuromuscular Cardiology

Cincinnati Children's Blog

What You Need To Know About Cardiomyopathy Right Now

BlogHeart Conditions

What You Need To Know About Cardiomyopathy Right Now

By Thomas Ryan, MD, PhD9/29/2016

Top Questions About Genetic Testing for Cardiomyopathy

BlogHeart Conditions

Top Questions About Genetic Testing for Cardiomyopathy

By Thomas Ryan, MD, PhD8/27/2015

My Locations

My Education

BS: Wichita State University, Wichita, KS, 1996. 

PhD: University of Alabama at Birmingham, Birmingham, AL, 2004.

MD: University of Alabama at Birmingham, Birmingham, AL, 2005.

Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2006-2009.

Fellowship: Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2009-2012.

Advanced Fellowship: Pediatric Heart Failure/Transplant, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2012-2013.

Certification: American Board of Pediatrics, 2010; American Board of Pediatrics, Sub-board of Pediatric Cardiology, 2012.

My Publications

Selected Publication

New-onset diabetes after pediatric heart transplantation: A review of the Pediatric Heart Transplant Study. Sparks, JD; Cantor, RS; Pruitt, E; Kirklin, JK; Carboni, M; Dreyer, W; Kindel, S; Ryan, TD; Morrow, WR. Pediatric Transplantation. 2019; 23.

Preparing the Cardiovascular Workforce to Care for Oncology Patients. Hayek, SS; Ganatra, S; Lenneman, C; Scherrer-Crosbie, M; Leja, M; Lenihan, DJ; Yang, E; Ryan, TD; Liu, J; Carver, J; et al. Journal of the American College of Cardiology. 2019; 73:2226-2235.

Contemporary Outcomes of Pediatric Restrictive Cardiomyopathy: A Single-Center Experience. Wittekind, SG; Ryan, TD; Gao, Z; Zafar, F; Czosek, RJ; Chin, CW; Jefferies, JL. Pediatric Cardiology. 2019; 40:694-704.

Treatment exposures stratify need for echocardiographic screening in asymptomatic long-term survivors of hematopoietic stem cell transplantation. Rotz, SJ; Powell, A; Myers, KC; Taylor, MD; Jefferies, JL; Lane, A; El-Bietar, JA; Davies, SM; Dandoy, CE; Ryan, TD. Cardiology in the Young. 2019; 29:338-343.

Cardiopulmonary Aerobic Fitness Assessment During Maximal and Submaximal Exercise Testing in Pediatric Oncology Patients After Chemotherapy. Powell, AW; Nagarajan, R; Mays, WA; Chin, C; Knilans, TK; Knecht, SK; Amos, MA; Gerdes, YM; Ryan, TD. American Journal of Clinical Oncology: cancer clinical trials. 2018; 41:1058-1061.

Cardiovascular Disease in Survivors of Childhood Cancer: Insights Into Epidemiology, Pathophysiology, and Prevention. Armenian, SH; Armstrong, GT; Aune, G; Chow, EJ; Ehrhardt, MJ; Ky, B; Moslehi, J; Mulrooney, DA; Nathan, PC; Ryan, TD; et al. Journal of Clinical Oncology. 2018; 36:2135-2144.

Obesity class does not further stratify outcome in overweight and obese pediatric patients after heart transplantation. Ryan, TD; Zafar, F; Siegel, RM; Villa, CR; III, BR; Chin, C. Pediatric Transplantation. 2018; 22:e13161-e13161.

Long-term systolic function in children and young adults after hematopoietic stem cell transplant. Rotz, SJ; Dandoy, CE; Taylor, MD; Jodele, S; Jefferies, JL; Lane, A; El-Bietar, JA; Powell, AW; Davies, SM; Ryan, TD. Bone Marrow Transplantation. 2017; 52:1443-1447.

Central Arterial Function Measured by Non-invasive Pulse Wave Analysis is Abnormal in Patients with Duchenne Muscular Dystrophy. Ryan, TD; Parent, JJ; Gao, Z; Khoury, PR; Dupont, E; Smith, JN; Wong, B; Urbina, EM; Jefferies, JL. Pediatric Cardiology. 2017; 38:1269-1276.

Utility of Echocardiography in the Assessment of Left Ventricular Diastolic Function and Restrictive Physiology in Children and Young Adults with Restrictive Cardiomyopathy: A Comparative Echocardiography-Catheterization Study. Ryan, TD; Madueme, PC; Jefferies, JL; Michelfelder, EC; Towbin, JA; Woo, JG; Sahay, RD; King, EC; Brown, R; Moore, RA; et al. Pediatric Cardiology. 2017; 38:381-389.