Center for Autoimmune Genetics and Etiology

Fig A: These images show the deposition of immune complexes and the complement protein C3, as analyzed by immunofluorescence. PAS-stained kidney sections were analyzed for renal lesion scores, which showed that miR-130b agomir ame-liorated interferon-α-accelerated lupus nephritis (LN) in mice.

Featured Research

Mimics of MicroRNA-130b May Hold a Key to Blocking Lupus-Related Kidney Damage

Experts have known for some time that Type I interferon (IFN) plays a critical role in the progression of lupus nephritis (LN), a dangerous complication that affects as many as 60 percent of people with lupus at some point in their lives.

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Research and Training Details

Faculty11
Joint Appointment Faculty3
Research Fellows and Post Docs8
Research Graduate Students12
Total Annual Grant Award Dollars$5,802,219
Total Publications40