Adolescent-onset type 2 diabetes places children at risk for early complications. We do not know if diabetes in adolescents effects the brain leading to changes in the brain blood vessels, brain structure or cognitive function. We are currently investigating the effects of type 2 diabetes on the brain in adolescents.

An image of the brain.


Shared Discovery Award, Cincinnati Children’s Hospital Medical Center. The Cincinnati Diabetes and Obesity Center, The University of Cincinnati. 

Publications from this Study

Redel JM, DiFrancesco M, Vannest J, Altaye M, Beebe D, Khoury J, Dolan LM, Lee G, Brunner H, Holland S, Brady C, Shah AS. Brain gray matter volume differences in obese youth with type 2 diabetes: a pilot study. J Pediatr Endocrinol Metab. 2018 Mar 28;31(3):261-268.

Brady CC, Vannest J, Dolan LM, Kadis D, Lee G, Holland S, Khoury J, Shah AS.  Obese Adolescents with Type 2 Diabetes Perform Worse than Controls on Cognitive and Behavioral Assessments. Pediatr Diabetes. 2017 Jun;18(4):297-303.