Shah Lab
Type 2 Diabetes and the Brain

Type 2 Diabetes and the Brain

Teens with type 2 diabetes appear to be at risk for early health complications. We do not know if diabetes in adolescents has effects the brain leading to changes in the brain blood vessels, brain structure or cognitive function. We are currently investigating the effects of type 2 diabetes on the brain in adolescents.

An image of the brain.


Shared Discovery Award, Cincinnati Children’s Hospital Medical Center. The Cincinnati Diabetes and Obesity Center, The University of Cincinnati. 

Publications from this Study

Redel, JM; DiFrancesco, M; Lee, GR; Ziv, A; Dolan, LM; Brady, CC; Shah, AS. Cerebral Blood Flow is Lower in Youth with Type 2 Diabetes Compared to Obese Controls. Pediatr Diabetes. 2022 Jan 10.

Redel, JM; Dolan, LM; Shah, AS. Youth-onset Type 2 Diabetes and the Developing Brain. Curr Diab Rep. 2019 Jan 21;19(1):3.

Redel, JM; DiFrancesco, M; Vannest, J; Altaye, M; Beebe, D; Khoury, J; Dolan, LM; Lee, G; Brunner, H; Holland, S; Brady, C; Shah, AS. Brain gray matter volume differences in obese youth with type 2 diabetes: a pilot study. J Pediatr Endocrinol Metab. 2018 Mar 28;31(3):261-268.

Brady, CC; Vannest, J; Dolan, LM; Kadis, D; Lee, G; Holland, S; Khoury, J; Shah, ASObese Adolescents with Type 2 Diabetes Perform Worse than Controls on Cognitive and Behavioral Assessments. Pediatr Diabetes. 2017 Jun;18(4):297-303.