Surgical or Medical Treatment for Pediatric Type 2 Diabetes
Bariatric surgery in teens has beneficial effects on weight loss. Initial studies show bariatric surgery may also help improve blood glucose control in teens with type 2 diabetes. We are studying the effects of bariatric surgery on blood glucose control and diabetes related health outcomes. We are comparing surgery to newer type 2 diabetes medications to see if the same outcomes can be achieved with medications and lifestyle modification.
Funding
This work is funded through research grants from the NIH and in part by Cincinnati Children's Hospital Medical Center
Publications from this Study
Shah, AS; Nadeau, KJ; Dabelea, D; Redonda, M. Spectrum of Phenotypes and Causes of Type 2 Diabetes in Children. Annu Rev Med. 2022 Jan 27;73:501-515.
Shah, AS; Helmrath, MA; Inge, TH; Xanthakos, SA; Kelsey, MM; Jenkins, T; Trout, AT; Browne, L; Nadeau, KJ. Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP). BMJ Open. 2021 Aug 13;11(8):e047766.
Shah, AS; Nadeau, KJ. The Changing Face of Pediatric Diabetes. Diabetologia. 2020 Apr;63(4):683-691.
Shah, AS; Nadeau, KJ; Helmrath, MA; Inge, TH; Xanthakos, S; Kelsey, MM. Metabolic Outcomes of Surgery in Youth with Type 2 Diabetes. Seminars in Pediatric Surgery Metabolic outcomes of surgery in youth with type 2 diabetes. Semin Pediatr Surg. 2020 Feb;29(1):150893. Epub 2020 Jan 25.
Bjornstad, P; Hughan, K; Kelsey, M; Shah, AS; Lynch, J; Nehus, E; Mitsnefes, M; Jenkins, T; Xu, P; Xie, C; Inge, T; Nadeau, K. Effect of Surgical versus Medical Therapy on Diabetic Kidney Disease in Severely Obese Adolescents with Type 2 Diabetes. Diabetes Care. 2020 Jan;43(1):187-195.
