Shah Lab
Surgical or Medical Treatment for Pediatric Type 2 Diabetes

Surgical or Medical Treatment for Pediatric Type 2 Diabetes

Bariatric surgery in teens has beneficial effects on weight loss. Initial studies show bariatric surgery may also help improve blood glucose control in teens with type 2 diabetes. We are studying the effects of bariatric surgery on blood glucose control and diabetes related health outcomes. We are comparing surgery to newer type 2 diabetes medications to see if the same outcomes can be achieved with medications and lifestyle modification.

Surgical or Medical Treatment for Pediatric Type 2 Diabetes


This work is funded through research grants from the NIH and in part by Cincinnati Children's Hospital Medical Center

Publications from this Study

Shah, AS; Nadeau, KJ; Dabelea, D; Redonda, M. Spectrum of Phenotypes and Causes of Type 2 Diabetes in Children. Annu Rev Med. 2022 Jan 27;73:501-515.

Shah, AS; Helmrath, MA; Inge, TH; Xanthakos, SA; Kelsey, MM; Jenkins, T; Trout, AT; Browne, L; Nadeau, KJ. Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP). BMJ Open. 2021 Aug 13;11(8):e047766.

Shah, AS; Nadeau, KJ. The Changing Face of Pediatric Diabetes. Diabetologia. 2020 Apr;63(4):683-691.

Shah, AS; Nadeau, KJ; Helmrath, MA; Inge, TH; Xanthakos, S; Kelsey, MM. Metabolic Outcomes of Surgery in Youth with Type 2 Diabetes. Seminars in Pediatric Surgery Metabolic outcomes of surgery in youth with type 2 diabetes. Semin Pediatr Surg. 2020 Feb;29(1):150893. Epub 2020 Jan 25.

Bjornstad, P; Hughan, K; Kelsey, M; Shah, AS; Lynch, J; Nehus, E; Mitsnefes, M; Jenkins, T; Xu, P; Xie, C; Inge, T; Nadeau, K. Effect of Surgical versus Medical Therapy on Diabetic Kidney Disease in Severely Obese Adolescents with Type 2 Diabetes. Diabetes Care. 2020 Jan;43(1):187-195.