Gene Delivery Core
Contact the Co-Directors
Jose Cancelas, MD, PhD
jose.cancelas@cchmc.org
Carolyn Lutzko, PhD
carolyn.lutzko@cchmc.org
Services
- Integrating vectors that include (i) γ-retrovirus, (ii) lentivirus and (iii) foamy virus vectors
- DNA virus vectors that include AAV and adenovirus vectors
- Access to the broader hematology research community on new technologies on design and production of vectors along with feasibility studies on titers
- Process development and scale-up of vectors to support a future GMP production, and to provide pilot medium scale GLP grade vector preparations (produced using the same methodology for the eventual GMP production) for preclinical pharm/tox studies and transduction optimization studies
