Integrating Basic and Clinical Research to Enhance Understanding of Human Reproduction
Reproductive science includes many aspects of biology, from gamete formation and early pregnancy events to the development of sex-specific reproductive organs.
Reproductive science also involves developmental and stem cell biology. Stem cell biology is a critical part of our work. Stem cell techniques helped create transgenic pre-clinical models for research and assisted reproductive therapies that benefit people around the world.
We collaborate with many other researchers within the divisions of Developmental Biology, Urology, and Pediatric and Adolescent Gynecology, as well as the Perinatal Institute and the Center for Stem Cell and Organoid Medicine (CuSTOM).
Our Research
Our faculty, students, fellows and research assistants conduct studies within our specialized labs. Research areas of focus include a wide range of topics. Some examples are:
- Differentiation of germline cells into egg and sperm
- Effects of cannabinoids on pregnancy
- Epigenetic reprogramming (molecular changes after fertilization that allow a new organism to form)
- Implantation and decidualization
- In vitro fertilization
- Oncofertility
- Placentation
- Preterm birth
- Reproductive endocrinology
- Roles of vascular and immune cells in reproduction and fetal development
We believe that positive reproductive health is associated with overall health for men and women. We strive to increase the impact of reproductive biology locally, nationally and internationally.
Research by the Numbers
The reproductive sciences researchers at Cincinnati Children’s are highly successful at attracting grant support for our work and publishing results in top scientific journals. Our research team and faculty members secure funding from many organizations, including government agencies such as the Eunice Kennedy Shriver National Institute of Child Health and Human Development (part of the National Institutes of Health) as well as public and private foundations.
