At Cincinnati Children’s, we’re committed to changing the outcomes for our patients and also those with cerebral palsy (CP) across the world. Our team participates in multiple clinical research trials, registries, scientific discovery and other initiatives to advance the knowledge and care for everyone with CP.

Cerebral Palsy Research Network

Charles B. Stevenson, MD, FAANS, is a lead investigator for the Cerebral Palsy Research Network (CPRN), a multicenter collaboration focused on advancing treatments and outcomes for people with CP. Cincinnati Children’s participates in the group’s cerebral palsy registry, which brings together treatment and outcomes data from CPRN members. The registry data helps inform improvements to CP treatments, outcomes and future research.

Global Work to Tackle Surgical Recommendations

James McCarthy, MD, MHCM, is an international expert on cerebral palsy surgical interventions. He recently formed a panel of experts from 15 institutions around the world with the goal of developing standardized surgical guidelines for children with CP. These guidelines will outline a procedure’s appropriateness based on patient-specific symptoms, medical history and test results. This work should help eliminate the confusion patients and families currently experience when they receive conflicting surgical recommendations.

Scientific Discovery Identifies Cause of Muscle Contractures

Groundbreaking research, from the lab of pediatric orthopaedic surgeon Roger Cornwall, MD, uncovered not only the root cause of muscle contractures, but also how to potentially prevent them. Previously, physicians and researchers hadn’t historically known the cause of contractures (the secondary loss of flexibility in children with CP or brachial plexus birth injury). The Cincinnati Children’s team discovered that these contractures are related to impaired longitudinal muscle growth and that medication might be the answer to stop them. Since then, they have engaged in additional lab-based research to bring this work one step closer to clinical trials and ultimately treating patients.