Cincinnati Children’s participates in clinical trials organized by the International Histiocyte Society for patients with diagnoses such as hemophagocytic lymphohistiocytosis (HLH) and Langerhans cell histiocytosis (LCH). Immune Deficiency and Histiocytosis team physicians will determine if your child with HLH or LCH is eligible for or may benefit from participating in any ongoing therapeutic or diagnostic research.

Additionally, all patients who are evaluated and diagnosed with an immune system disorder are offered the opportunity to participate in the Immunodeficiency Registry. As a part of this registry, blood may be stored for  genetic testing or shared with scientists around the world who investigate a variety of disorders.

Finally, laboratory researchers in the Cancer and Blood Diseases Institute work together with physicians to translate breakthroughs from the lab to the clinic. Many of our physician-researchers hold leadership positions in national cooperative groups that bring phase I clinical trials to medical centers around the country.

Many of these trials are available at only a few institutions in the United States, and others are not available anywhere else.

Featured Clinical Trial for Immune Deficiency and Histiocytosis