Jonathan C. Howell, MD, PhD

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-636-4744


Type 1 and type 2 diabetes mellitus; endocrinopathy in bone marrow failure syndromes; growth disorders; thyroid disorders

Jonathan C. Howell, MD, PhD, is board certified in both pediatrics and pediatric endocrinology. He has been on the faculty of Cincinnati Children’s Hospital Medical Center within the Department of Pediatrics of the University of Cincinnati College of Medicine since 2012.

Dr. Howell is an assistant professor of pediatrics in the Division of Endocrinology within the UC Department of Pediatrics. His main clinical focus is diabetes as well as providing care for patients with endocrine disorders, including growth, thyroid, pituitary, pubertal, and adrenal dysfunction. Dr. Howell’s research focuses on the effects of congenital anemias and cancer on the endocrine system and the outcomes of chemotherapy, radiation, transfusions, and chronic steroid therapy on endocrine hormone function. 

Dr. Howell received his Bachelor of Arts degree from Hanover College. He received his PhD from Indiana University and his MD from Indiana University School of Medicine.

Dr. Howell completed his pediatric internship and residency at Cincinnati Children’s Hospital Medical Center, where he also served as chief resident. He also obtained his fellowship training from Cincinnati Children’s.

BA: Hanover College, Hanover, IN, 1997.

PhD: Indiana University (Edward F. Srour, thesis adviser), Indianapolis, IN, 2003.

MD: Indiana University School of Medicine, Indianapolis, IN, 2005.

Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2005-2008.

Chief Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2008-2009.

Endocrinology Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2009-2012

Certification: Pediatrics, 2008; Pediatric Endocrinology, 2013.

McCracken, Kyle, Jonathan C. Howell, James M. Wells, Jason R. Spence. Generating human intestinal tissue from pluripotent stem cells in vitro. Nature Protocols. 2011;6(12): 1920-1928.

Howell, Jonathan C, James M. Wells. Generating intestinal tissue from stem cells: potential for research and therapy. Regenerative Medicine. 2011;6(6): 743-755. 

Howell, Jonathan C, Mandi Cafasso, Philippe F. Backeljauw. Superior mesenteric artery syndrome as a presentation of Graves’ disease in adolescence. EndoTrends. 2011;17(3): 1-3.

Case, Jamie, Tamara L. Horvath, Jonathan C. Howell, Mervin C. Yoder and Edward F. Srour. Clonal multilineage differentiation of murine common pluripotent stem cells isolated from both skeletal muscle and adipose stromal cells. Annals of the New York Academy of Sciences. 2004;1044: 1-18.

Howell, Jonathan C., Wei-Hua Lee, Paul Morrison, Jin Zhong, Mervin C. Yoder, and Edward F. Srour. Pluripotent stem cells identified in multiple murine tissues. Annals of the New York Academy of Sciences. 2003.  996: 158-173.

Howell, Jonathan C, Mervin C. Yoder. Adult Stem Cell Plasticity Defined. NeoReviews. 2003;4(7): 181-186. 

Royer, Cassandra L, Jonathan C. Howell, Paul R. Morrison, Edward F. Srour, Mervin C. Yoder. Muscle-derived CD45+Sca-1+c-kit- progenitor cells give rise to skeletal muscle myotubes in vitro. In Vitro Cellular and Developmental Biology -- Animal. 2003;38(9): 512-517.

Howell, Jonathan C, Mervin C. Yoder, Edward F. Srour. Hematopoietic potential of murine skeletal muscle-derived CD45-Sca-1+c-kit- cells. Experimental Hematology. 2002;30(8): 915-924.