Academic and Research Committee (ARC) Awards

These grants support multi-disciplinary programs that can become self-sustaining within one to three years. Awardees this year are:

Topic PI Division Title
Education Keith Marsolo, PhD Biomedical Informatics Enabling Scalable Data Collection, Decision Support and Quality Management
Clinical/Research Mary Greiner, MD General Pediatrics Integrated Systems Data Hub for Foster Care
Clinical/Research Lesley Breech, MD Pediatric and Adolescent Gynecology Fertility Care and Preservation
Clinical/Research Lee Ann Conard, RPh, DO, MPH Adolescent Medicine Transgender Clinic Expansion
Clinical/Research Andrew Dauber, MD, MMSc Endocrinology Cincinnati Children's Undiagnosed Diseases Program
Clinical/Research Gurjit Khurana Hershey, MD, PhD* Asthma Research Personalized Treatment Algorithms for Difficult-to-Treat Asthma
Research Lilliam Ambroggio, PhD Hospital Medicine Metabolomics of Community Acquired Pneumonia
Research Claire Chougnet, PhD Immunobiology Perinatal Infection and Inflammation
Research James Mulloy, PhD Cancer and Blood Diseases Institute Avatars
*Multi-PI includes Theresa Guilbert, MD, MS, General Pediatrics and Carolyn Kercsmar, MD, Pulmonary Medicine

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Center for Clinical and Translational Science and Training (CCTST) Program Awards

Cincinnati Children’s partners with the University of Cincinnati and other institutions to support programs funded through the Center for Clinical and Translational Science and Training (CCTST).

Type Title PI PI Department/Division Co-Is Co-I Department/Division
T1 Improved DTI and fMRI of the neonatal brain Jean Tkach, PhD Imaging Research Center Randy Giaquinto Radiology
T1 Reduced expression of Kv4.2 as disease-causing and treatable mechanism in autism Christina Gross, PhD Neurology Tori Schaefer Psychiatry
T1 Characterization of belatacept-refractory T cells in kidney transplantation David Hildeman, PhD Immunobiology Steve Woodle Surgery
T1 A new hydrogen peroxide-activated agent that selectively targets AML cancer cells Eddie Merino, PhD Chemistry James Mulloy, PhD Experimental Hematology and Cancer Biology
T1 Prevention of red cell storage damage by a combinatorial approach Jose Cancelas Perez, MD, PhD Hoxworth Blood Center   Experimental Hematology and Cancer Biology
Jr.T1 Role of CD38Bright CD8+ effector Memory T cells in a GVDH Pooja Khandelwal, MD Cancer and Blood Diseases Institute Rebecca Marsh, MD Cancer and Blood Diseases Institute
Core Hyperpolarized-gas Core: Lighting up the lungs Jason Woods, PhD Pulmonary Medicine Zackary Cleveland, PhD Pulmonary Medicine
Core Epigenomics Data Analysis Core Artem Barski, PhD Allergy and Immunology and Human Genetics    
Core YR2 Pediatric Lower-Airway Specimen Core Theresa Guilbert, MD, MS Pulmonary Medicine John Clancy, MD Pulmonary Medicine
Core YR2 Translational Genomics Analysis Core Kenneth Kaufman, PhD Center for Autoimmune Genomics and Etiology John Harley, MD, PhD Center for Autoimmune Genomics and Etiology
JiT Harnessing The Hippo Signaling Pathway For Treating MPNSTs Qing Richard Lu, PhD Experimental Hematology and Cancer Biology    
JiT Allele-specific ChIP-seq analyses of hnRNP U to uncover Xist RNA binding sites Yuya Ogawa, PhD Reproductive Sciences    
JiT Transcriptome Analysis of a Ras-Inhibitory Compound in High-Risk B-ALL Nicolas Nassar, PhD Experimental Hematology and Cancer Biology    
JiT Epigenetic signature of memory Th2 cells in allergy Yrina Rochman, PhD Immunobiology    
JiT Chemical Dissection of IRAK and FLT3-ITD in AML Daniel Starczynowski, PhD Experimental Hematology and Cancer Biology    
JiT Targeting adaptive endoplasmic reticulum stress for neurofibroma therapy Jianqiang Wu, MD, MS Experimental Hematology and Cancer Biology    
Process & Methods It's the Process that Matters: Understanding the Risks in Clinical Research Richard Ittenbach, PhD Biostatistics and Epidemiology    
Process & Methods The HopeFest ePassport Melinda Butsch Kovacic, MPH, PhD Asthma Research Bradley Sherman Hopefest Health
Process & Methods Adjustment for Differential Loss to Follow-up in ECS Alonzo Folger, PhD Biostatistics and Epidemiology Katherine Bowers, PhD, MPH Biostatistics and Epidemiology
Process & Methods Automated De-Identification of School-Based Mental Health Interviews John Pestian, PhD, MBA Biomedical Informatics    
Process & Methods Strategies to Recruit Community Health Workers in Immigrant Communities Kelly Kamimura-Nishimura, MD Developmental and Behavioral Pediatrics Karen Burkett, PhD, APRN, PPCNP  
TRP Child Adult Relationship Enhancement for Foster Care Erica Messer, PsyD Behavioral Medicine and Clinical Psychology    
TRP Avondale Moms Empowered to Nurse! Julie Ware, MD, MPH General and Community Pediatrics    
Retreats, Workshops & Symposia Introduction to Community Based Participatory Research Lisa Vaughn, PhD      
Retreats, Workshops & Symposia 2015 Mentorship Symposium Jessica Kahn, MD, MPH      
Retreats, Workshops & Symposia 27th Annual Workshop on MR Angiography-Educational Session Charles Dumoulin, PhD      
Retreats, Workshops & Symposia Biology and Therapy of Adolescent and Young Adult Sarcomsas Joseph Pressey, MD      

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Center for Pediatric Genomics Awards

The Center for Pediatric Genomics (CpG) has established a fund to distribute $1 million annually among projects that accelerate innovative research, development, and implementation of genomic science. Awardees this year are:

Faculty Division Title
Vidya Chidambaran, MD Anesthesia Genetic-epigenetic approach to predict chronic post-surgical pain in children
Andrew Dauber, MD Endocrinology Confronting the Dreaded VUS: Validation of Exome Sequencing Candidates in Human Growth Disorders Using Genome Editing
David Haslam, MD Infectious Diseases Fecal Metagenomics as a Tool to Identify and Mitigate Risk of Bloodstream Infection in High Risk Children
Hong Ji, PhD Asthma Research Epigenetic Mediation of Genetic Effects in Childhood Asthma
Andrew Lindsley, MD, PhD Artem Barski, PhD Allergy and Immunology Epigenetic Mechanisms of Humoral Immune Deficiency in Kabuki Syndrome
Q. Richard Lu, PhD Experimental Hematology and Cancer Biology Functional Genomic Analysis of Oncogenic Pathways in Primary and Recurrent Medullablastomas
Melanie Myers, PhD Human Genetics A Decision Aid for Return of Results Across Genomic Sequencing Studies
Mihaela Pavlicev, PhD Center for the Prevention of Preterm Birth The Contribution of Non-Coding Genome to Placental Defects: The Establishment and Application of a Novel Tool to Reliably Map and Quantify Active Enhancers
Matthew Weirauch, PhD Center for Autoimmune Genomics and Etiology Etiology of Inflammatory Diseases Revealed by Shared Molecular Mechanisms
Susanne Wells, PhD Oncology HPV Infection of Human Epidermis: Single Cell Resolution and Metabolomic Consequences

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Children’s Health Research Career Development Award (CHRCDA)

This program provides $93,000 grants to support training physician-scientists to stimulate pediatric research across a variety of disciplines. This year’s awardees are:

Name Division Title of Research
Andrew Lindsley, MD, PhD Allergy and Immunology Pulmonary Ceramide Function in Allergic Asthma
Kasiani Myers, MD Cancer and Blood Diseases Institute - Bone Marrow Transplant and Immune Deficiency Hematopoietic Defects in Shwachman Diamond Syndrome
Matthew Alder, MD, PhD Cancer and Blood Diseases Institute - Bone Marrow Transplant and Immune Deficiency A Potential Role for olfm4 In Sepsis
Kathryn Weaver, MD Human Genetics Ttc21b Is Critical for Craniofacial Development

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Cincinnati Children's Innovation Fund

The Cincinnati Children’s Innovation Fund is designed to accelerate the commercialization of discoveries, innovations, projects or products. Recipients this year are:

PI Title
Hector Wong, MD Rapid Biomarker Assay for Septic Shock Mortality Risk Stratification
Bruce Trapnell, MD, MS A Pilot Study of Pioglitazone Therapy of Autoimmune Pulmonary Alveolar Proteinosis
Doug Millay, PhD Harnessing Cell Fusion to Deliver Therapeutic Material to Skeletal Muscle
Yizhao Ni, PhD Automated Patient Identification for Research Studies in Emergency Departments
Stuart Goldstein, MD, FAAP, FNKF Development of Electronic Health Record Diagnostic Service to Identify and Direct Biomarker Assessment in Critically Ill Children at Risk for Acute Kidney Injury
Abby Hess, DNP, APRN, FNP-BC Development of a Game Application that Interfaces with Anesthesia Equipment to Facilitate Improved Anesthesia Induction Experiences and Post-Operative Outcomes in Pediatric Patients

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Adare Drug Repurposing and Optimization Innovation Fund

This new fund focuses on research to help medications initially developed for adults better meet the needs of children. This year's recipient is:

PI Title
Gurjit (Neeru) Hershey, MD, PhD Biomarker of Poor Steroid Treatment Responder

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Alexion Rare Disease Innovation Fund

Alexion Pharmaceuticals and Cincinnati Children’s have established a collaboration to fund the advancement of research in rare disease. This year’s recipient is: 

PI Title
Pranavkumar Shivakumar, PhD Controlling Inflammation to Treat Biliary Atresia

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Fifth Third Bank/Charlotte R. Schmidlapp Women Scholars Awards

This program provides grants to support the academic career development of women faculty who have demonstrated academic potential and leadership skills as they progress toward the ranks of associate and full professor. This year’s awardees are:

Name Division Year
Fumika Hamada, PhD Visual Systems Group/Pediatric Ophthalmology 2015-2016
Patricia Fulkerson, MD, PhD Allergy and Immunology 2016-2017
Ellen Lipstein, MD, MPH (1 year award) Adolescent Medicine 2016

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GAP Funding Awards

This program provides one year of support to bridge gaps in R01-level funding or equivalent. Awardees this year are:

PI Division Grant Title Funding Round
Rulang Jiang, PhD Developmental Biology Molecular Genetic Analysis of Craniofacial Development 2015 - July
Kimberly Yolton, PhD/Kim Cecil, PhD General Pediatrics/Radiology Impact of PBDE and PFC Exposures on Internalizing Behaviors and Neuroimaging Outcomes 2015 - November
Kenneth Campbell, PhD Developmental Biology and Neurosurgery Molecular mechanisms controlling formation of basal ganglia circuitry 2015 - November
Sanjoy Das, PhD Reproductive Sciences Hoxa10-cMet pathway regulates uterine decidualization and angiogenesis 2015 - November
Paul Andreassen, PhD Cancer and Blood Diseases Institute A novel and rapid system to functionally stratify BRCA2 variants in human cells 2016 - March
Satoshi Namekawa, PhD Reproductive Sciences DNA Damage Response Pathways in meiotic sex chromosome inactivation 2016 - March
Yan Xu, PhD/James Bridges, PhD Pulmonary Biology/Neonatology and Pulmonary Biology Glucocorticoid regulation of mesenchyymanl cell maturation during lung development 2016 - March

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Place Outcome Awards

This program, administered by the James M. Anderson Center for Health Systems Excellence, provides grants to stimulate the development of health services and quality improvement research at Cincinnati Children’s and to ensure optimal implementation of clinical and operational innovations in the care delivery system. Awardees receiving funding are:

  Project Period
PI Name Division Name CO PI Name Award Start Date Award End Date Award Title
Kristen Copeland, MD General and Community Pediatrics 7/1/2015 6/30/2017 Innovations in management of obesity and inactivity in pediatric primary care
Natoshia Cunningham, PhD Developmental and Behavioral Pediatrics 7/1/2015 6/30/2017 Improving screening and care for anxious youth with functional abdominal pain
Chris Dandoy, MD, MSc Bone Marrow Transplantation and Immune Deficiency 7/1/2015 6/30/2017 Factorial design to improve sleep hygiene in patients and families undergoing stem cell transplant
Mark Paterno, PT, PhD, MBA, SCS Occupational Therapy and Physical Therapy and Sports Medicine 7/1/2015 6/30/2017 Redefining rehabilitation after anterior cruciate ligament reconstruction
Thomas Sitzman, MD Plastic Surgery 7/1/2015 6/30/2017 Standardizing assessment and improving outcomes in cleft palate surgery
Kathleen Walsh, MD, MSc James M. Anderson Center/Behavioral Medicine & Psychology Lori Crosby, PsyD 7/1/2015 6/30/2017 A multifaceted intervention to improve adherence to hydroxyurea among children with sickle cell disease

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Procter Scholar Grant

The Procter Scholar Program supports faculty members from the Departments of Pediatrics, Surgery, Radiology, Patient Services, and Anesthesia who are committed to pursuing academic research careers.

Year Recipient Division Title
Second Year Ernest Pedapati, MD Psychiatry Cortical Plasticity and Neuromodulation of Social Cognition in Autism Spectrum Disorders
Second Year Hitesh Deshmukh, MD, PhD Neonatology Developmental Regulation of Host Resistance and Innate Immune Response by Intestinal Microbes
Third Year Andrew Lindsley, MD, PhD Allergy and Immunology ORMDL3-Driven Airway Inflammation Triggers Pediatric Asthma
Third Year Jeffrey Tenney, MD, PHD Neurology Seizure Generator Location and Neurocognitive Deficits in CAE
Third Year Jennifer Davis, DO Oncology ETV2 Role in Embryonic and Tumor Induced Lymphangiogenesis
Third Year Patrick McGann, MD Hematology A Phase I/II Study of Hydroxyurea for Children with Sickle Cell Anemia in Angola
Third Year (only 6 months of funding) Brian Varisco, MD Critical Care Medicine Chymotrypsin Like Elastase-1 Regulates Pulmonary Vascular Morphogenisis

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Research, Innovation & Pilot (RIP) Funding Awards

This program provides grants to support collecting preliminary data for innovative and essential projects considered to be good candidates for future external funding. Awardees receiving funding this year include:

PI Division Grant Title Funding Round
Kakajan Komurov, PhD Experimental Hematology Global Cryptic Transcription: a novel clinically significant phenotype that dictates response to cancer therapy 2015 - July
Michael Jankowski, PhD Anesthesia Growth Hormone, Pediatric Pain and Sensory Development 2015 - July
Samantha Brugmann, PhD Plastic Surgery/Developmental Biology Using the Developing Embryo to Identify Factors that Influence the Primary Ciliome 2015 - July
Edith Janssen, PhD Immunobiology Immunogenicity of MRg-HIFU mediated tumor ablation 2015 - July
Daniel Grossoehme Pulmonary Medicine Less depression, better adherence: addressing parental spiritual struggle in CF 2015 - November
Katherine Holland, MD, PhD Neurology TMS Measures of Brain Excitability in People Genetically at Risl fore Seizures 2015 - November
Nick Pratap, MB BChir, MRCPCH, FRCA Anesthesiology Gastric emptying of novel protein-and carbohydrate-rich clear liquids 2015 - November
Kenneth Setchell, PhD Pathology Global Metabolomics/lipidomics Study of Progressive Familial Intrahepatic Cholestasis 2015 - November
Shari Wade, PhD Physical Medicine and Rehabilitation Online Intervention to promote Quality of life in adolescent brain tumor survivors 2015 - November
Mohammad Azam, PhD Cancer Pathology A therapeutic strategy to eradicate the Leukemia Stem Cells in Acute myeloid leukemia (AML) 2015 - November
Biplap DasGupta, PhD, MS Cancer and Blood Diseases Institute  Therapeutic passenger vulnerability in GBM 2015 - November
Tony De Falco, PhD Reproductive Sciences Macrophage regulation of the spermatogonial stem cell niche 2015 - November
Simon Hogan, PhD Allergy and Immunology Ciproflaxxin driven antigen sampling through goblet cells in the predisposition of atopic susceptible mice to the development of food allergy 2015 - November
Jun Ma, PhD Biomedical Informatics Using embryos to monitor insulin-regulated metrernal metabolic states 2015 - November
Satoshi Namekawa, PhD Reproductive Sciences Germline epigenome and programmed differentiation during spermatogenesis 2015 - November
Saulius Sumanas, PhD Developmental Biology Characterization of a novel hematopoietic site in zebrafish 2015 - November
Fumika Hamada, PhD Ophthalmology Molecular mechanisms of starvation-induced temperature preference in Drosophilia 2016 - March
Xinhua Lin, PhD Developmental Biology Roles of Znhit1 in intestinal stem cell maintenance and differentiation 2016 - March
Daniel Starczynowski, PhD Cancer and Blood Diseases Institute Development of novel therapeutic modalities for Myelodysplastic syndromes 2016 - March
Daniel Lovell, MD, MPH/Diana Taft, PhD Rheumatology Intestinal Microbiome dysobiosis in oligoarthritis juvenile idiopathic arthritis 2016 - March
Assem Ziady, PhD Pulmonary Medicine Examining early pulmonary inflammation in CF 2016 - March

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Trustee Grant Awards

This program provides research funds for junior faculty to support rapid achievement of independent, sustained extramural funding for their research. This year’s awardees are:

Award Recipient Department/Discipline Title of Trustee Award Project
Theresa Alenghat Immunobiology Regulation of Intestinal Homeostasis by Commensal Bacteria-Derived Metabolites
Lilliam Ambroggio, PhD Hospital Medicine Identifying Etiology of Childhood Pneumonia with Metabolomics
Artem Barski, PhD Allergy and Immunology Epigenetic Suppression of IL4 Expression in T Cells
Sarah Beal, PhD Behavioral Medicine and Clinical Psychology Understanding Health and Wellbeing Among Adolescents in Protective Custody
Stephen Becker Behavioral Medicine and Clinical Psychology Phenotypic Correlates Distinguishing Sluggish Cognitive Tempo from ADHD
Katherine Bowers, PhD Biostatistics and Epidemiology Prenatal Maternal Distress and Offspring Neurodevelopment
Iouri Chepelev, PhD Center for Autoimmune Genomics and Etiology Functional Analysis of Lupus Disease SNPs Using Chromosome Conformation Capture
Zackary Cleveland, PhD Pulmonary Medicine Tissue Density and Specific Ventilation MRI in Models of Progressive Lung Disease
Steven Crone, PhD Neurosurgery Degeneration and Plasticity of Respiratory Circuits in ALS
Andrew Dauber, MD Endocrinology Functional and Developmental Characterization of Activation Mutations in CDKN1C
Patricia Fulkerson, MD-PhD Allergy and Immunology Roles of Helios and Aiolos in Eosinophil Development
Christina Gross, PhD Neurology MicroRNA-mediated Silencing of the Potassium Channel Kv4.2 in Epilepsy
Tzipi Horowitz-Kraus, PhD General and Community Pediatrics The Role of Executive Functions in Reading in Children with Dyslexia
Darren Kadis, PhD Neurology Mapping Language with fMRI-constrained MEG Effective Connectivity Analyses
Yu Lan, PhD Plastic Surgery Golgb1 in Craniofacial Development
Satish Madala, PhD Pulmonary Medicine Wilms' Tumor 1 - Regulation of Pulmonary Fibrosis
Jun Nakamura, PhD Neurosurgery Molecular characterization of choroid plexus cilia in a novel mouse mutant with communicating hydrocephalus
Catherine Quatman-Yates, PT-DPT Sports Medicine Autonomic Dysfunction: A Systemic Impairment and Therapeutic Target for Mild Traumatic Brain Injuries
Michael Rosen, MD-MS Gastroenterology, Hepatology and Nutrition Myeloid Cell-Derived IL-33 in Chronic IL-10-Deficient Colitis
Takuji Suzuki, PhD Pulmonary Biology Patient-Specific iPS Cells and a Novel Cell/Gene Therapy of Heredity PAP
Matthew Weirauch, PhD Center for Autoimmune Genomics and Etiology Viral Transcription Factor Interactions with Disease-Associated Genetic Variants
Mei Xin, PhD Experimental Hematology and Cancer Biology Regulation of Vascular Endothelial Network and Remodeling Through Hippo Signaling Pathway
Chunyue Yin, PhD Gastroenterology, Hepatology and Nutrition Molecular and Genetic Regulation of Congenital Polycystic Liver Diseases

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