Fig A. Novel biallelic LRBA mutations of nine patients appear along a schematic map of LRBA protein domains.

Featured Research

Breakthrough Therapy Improves Life for Children with LRBA Deficiency

Abatacept, a drug primarily used to treat arthritis, mimics the function of the CTLA4 protein. In children with this rare condition, the drug improved lung function and reduced other autoimmune symptoms.

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Research Fellows and Post Docs18
Research Graduate Students16
Total Annual Grant Award Dollars$4,953,470
Total Annual Industry Award Dollars$121,391
Total Publications124