De Falco Lab

Kumar, DL; DeFalco, T. A perivascular niche for multipotent progenitors in the fetal testis. Nature Communications. 2018; 9.

Sun, X; Ito, J; Potter, SJ; Dey, SK; DeFalco, T. Extragonadal oocytes residing in the mouse ovarian hilum contribute to fertility. Biology of Reproduction. 2017; 96:1060-1070.

Lin, Y; Barske, L; DeFalco, T; Capel, B. Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. Development (Cambridge). 2017; 144:1607-1618.

Potter, SJ; DeFalco, T. Role of the testis interstitial compartment in spermatogonial stem cell function. Reproduction. 2017; 153:R151-R162.

DeFalco, T; Potter, SJ; Williams, AV; Waller, B; Kan, MJ; Capel, B. Macrophages Contribute to the Spermatogonial Niche in the Adult Testis. Cell Reports. 2015; 12:1107-1119.

DeFalco, T; Bhattacharya, I; Williams, AV; Sams, DM; Capel, B. Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis. Proceedings of the National Academy of Sciences of USA. 2014; 111:E2384-E2393.

DeFalco, T; Saraswathula, A; Briot, A; Iruela-Arispe, ML; Capel, B. Testosterone Levels Influence Mouse Fetal Leydig Cell Progenitors Through Notch Signaling. Biology of Reproduction. 2013; 88.

Jameson, SA; Natarajan, A; Cool, J; DeFalco, T; Maatouk, DM; Mork, L; Munger, SC; Capel, B. Temporal Transcriptional Profiling of Somatic and Germ Cells Reveals Biased Lineage Priming of Sexual Fate in the Fetal Mouse Gonad. PLoS Genetics. 2012; 8:e1002575-e1002575.

DeFalco, T; Takahashi, S; Capel, B. Two distinct origins for Leydig cell progenitors in the fetal testis. Developmental Biology. 2011; 352:14-26.

Cool, J; DeFalco, TJ; Capel, B. Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning. Proceedings of the National Academy of Sciences of USA. 2011; 108:167-172.

Heinrich, A; DeFalco, T. Peritubular cells of the human testis: prostaglandin E(2)and more. Andrology. 2020; 8:903-914.

Nie, Y; Wilson, AF; DeFalco, T; Meetei, AR; Namekawa, SH; Pang, Q. FANCD2 is required for the repression of germline transposable elements. Reproduction. 2020; 159:659-668.

Heinrich, A; Potter, SJ; Guo, L; Ratner, N; DeFalco, T. Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis. Cell Reports. 2020; 31:107513-107513.

Kumar, DL; DeFalco, T. A perivascular niche for multipotent progenitors in the fetal testis. Nature Communications. 2018; 9.

Valiente-Alandi, I; Potter, SJ; Salvador, AM; Schafer, AE; Schips, T; Carrillo-Salinas, F; Gibson, AM; Nieman, ML; Perkins, C; Sargent, MA; et al. Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure. Circulation. 2018; 138:1236-1252.

Hulin, A; Anstine, LJ; Kim, AJ; Potter, SJ; DeFalco, T; Lincoln, J; Yutzey, KE. Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2018; 38:636-644.

Sun, X; Ito, J; Potter, SJ; Dey, SK; DeFalco, T. Extragonadal oocytes residing in the mouse ovarian hilum contribute to fertility. Biology of Reproduction. 2017; 96:1060-1070.

Lin, Y; Barske, L; DeFalco, T; Capel, B. Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. Development (Cambridge). 2017; 144:1607-1618.

Potter, SJ; DeFalco, T. Role of the testis interstitial compartment in spermatogonial stem cell function. Reproduction. 2017; 153:R151-R162.

Kumar, DL; DeFalco, T. Of Mice and Men: In Vivo and In Vitro Studies of Primordial Germ Cell Specification. Seminars in Reproductive Medicine. 2017; 35:139-146.

Potter, SJ; Kumar, DL; DeFalco, T. Origin and differentiation of androgen-producing cells in the gonads. Results and problems in cell differentiation. 2016; 58:101-134.

DeFalco, T; Potter, SJ; Williams, AV; Waller, B; Kan, MJ; Capel, B. Macrophages Contribute to the Spermatogonial Niche in the Adult Testis. Cell Reports. 2015; 12:1107-1119.