A photo of Jack Bleesing.

Jacob "Jack" J.H. Bleesing, MD, PhD

  • Co-Director, Diagnostic Immunology Laboratories
  • Associate Director, Immunodeficiency and Histiocytosis Program
  • Professor, UC Department of Pediatrics


Additional Languages

Dutch, German

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A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice. Schmitt, EG; Toth, KA; Risma, SI; Kolicheski, A; Saucier, N; Feliciano BerrĂ­os, RJ; Greenberg, ZJ; Leiding, JW; Bleesing, JJ; Thatayatikom, A; et al. JCI insight. 2022.

Gain-of-function defects in toll-like receptor 8 shed light on the interface between immune system and bone marrow failure disorders. Bleesing, J. Frontiers in Immunology. 2022; 13.

Reduced Intensity Conditioning Allogeneic Transplant for SCID Associated with Cartilage Hair Hypoplasia. Fitch, T; Bleesing, J; Marsh, RA; Chandra, S. Journal of Clinical Immunology. 2022.

Preemptive hematopoietic cell transplantation for asymptomatic patients with X-linked lymphoproliferative syndrome type 1. Tomomasa, D; Booth, C; Bleesing, JJ; Isoda, T; Kobayashi, C; Koike, K; Taketani, T; Sawada, A; Tamura, A; Marsh, RA; et al. Clinical Immunology. 2022; 237.

Ruxolitinib for the Treatment of Chronic GVHD and Overlap Syndrome in Children and Young Adults. Wang, YZ M; Teusink-Cross, A; Elborai, Y; Krupski, MC; Nelson, AS; Grimley, MS; Flannery, A; Mehta, PA; Bleesing, JJ; Chandra, S; et al. Transplantation. 2022; 106:412-419.

T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome. Kumar, D; Prince, C; Bennett, CM; Briones, M; Lucas, L; Russell, A; Patel, K; Chonat, S; Graciaa, S; Edington, H; et al. Blood. 2022; 139:369-383.

International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome. Dimitrova, D; Nademi, Z; Maccari, ME; Ehl, S; Uzel, G; Tomoda, T; Okano, T; Imai, K; Carpenter, B; Ip, W; et al. Journal of Allergy and Clinical Immunology. 2022; 149:410-421.e7.

Graft rejection markers in children undergoing hematopoietic cell transplant for bone marrow failure. Sabulski, A; Myers, KC; Bleesing, JJ; Duell, A; Lane, A; Teusink-Cross, A; Davies, SM; Jodele, S. Blood Advances. 2021; 5:4594-4604.

Daratumumab for the management of autoimmune cytopenias in children and young adults: a case series. Khandelwal, P; Teusink-Cross, A; Kumar, AR; Bleesing, JJ; Mehta, PA; Jordan, MB; Chandra, S; Davies, SM; Marsh, RA. British Journal of Haematology. 2021; 194:e84-e89.

Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function. Aluri, J; Bach, A; Kaviany, S; Chiquetto Paracatu, L; Kitcharoensakkul, M; Walkiewicz, MA; Putnam, CD; Shinawi, M; Saucier, N; Rizzi, EM; et al. Blood. 2021; 137:2450-2462.

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