A photo of Jack Bleesing.

Co-Director, Diagnostic Immunology Laboratories

Associate Director, Immunodeficiency and Histiocytosis Program

Professor, UC Department of Pediatrics

513-517-2234

513-636-3549

Board Certified

About Me

Additional Languages

Dutch, German

Clinical Interests

Immunobiology; translational research; immunologic methods development

Research Interests

Clinical investigation of primary immunodeficiency disorders (with emphasis on disorders of immuno dysregulation and B-cell disorders); immuno-reconstitution following blood and marrow transplantation; diagnostic immunology (with emphasis on flow cytometry)

Academic Affiliation

Professor, UC Department of Pediatrics

Clinical Divisions

Cancer and Blood Diseases, Immune Deficiencies and Histiocytosis, Bone Marrow Transplantation BMT, Leukemia, Hemophagocytic lymphohistiocytosisHLH, Rare Lung Diseases

My Locations

My Education

MD: University of Leiden, Leiden, The Netherlands, 1989.

PhD: University of Leiden, Leiden, The Netherlands, 2002.

Residency: Pediatrics, University of Florida, Gainesville, Florida, 1993.

Fellowship: Allergy/Immunology, Duke University Medical Center, Durham, North Carolina, 1995.

Fellowship: Clinical Laboratory Immunology, National Institutes of Health, Bethesda, Maryland, 2001.

My Publications

Daratumumab for the management of autoimmune cytopenias in children and young adults: a case series. Khandelwal, P; Teusink-Cross, A; Kumar, AR; Bleesing, JJ; Mehta, PA; Jordan, MB; Chandra, S; Davies, SM; Marsh, RA. British Journal of Haematology. 2021.

International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome. Dimitrova, D; Nademi, Z; Maccari, ME; Ehl, S; Uzel, G; Tomoda, T; Okano, T; Imai, K; Carpenter, B; Ip, W; et al. Journal of Allergy and Clinical Immunology. 2021.

Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function. Aluri, J; Bach, A; Kaviany, S; Chiquetto Paracatu, L; Kitcharoensakkul, M; Walkiewicz, MA; Putnam, CD; Shinawi, M; Saucier, N; Rizzi, EM; et al. Blood. 2021; 137:2450-2462.

Ruxolitinib for the treatment of chronic GVHD and overlap syndrome in children and young adults. Wang, YM; Teusink-Cross, A; Elborai, Y; Krupski, MC; Nelson, AS; Grimley, MS; Flannery, A; Mehta, PA; Bleesing, JJ; Chandra, S; et al. Transplantation. 2021.

Human Papillomavirus Oral- and Sero- Positivity in Fanconi Anemia. Sauter, SL; Zhang, X; Romick-Rosendale, L; Wells, SI; Myers, KC; Brusadelli, MG; Poff, CB; Brown, DR; Panicker, G; Unger, ER; et al. Cancers. 2021; 13.

Four Biomarkers Linked to Activation of Cluster of Differentiation 8-Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure. Leonis, MA; Miethke, AG; Fei, L; Maynor, S; Chapin, CA; Bleesing, JJ H; Alonso, EM; Squires, RH. Hepatology. 2021; 73:233-246.

Experience with a Reduced Toxicity Allogeneic Transplant Regimen for Non-CGD Primary Immune Deficiencies Requiring Myeloablation. Chandra, S; Chandrakasan, S; Dávila Saldaña, BJ; Bleesing, JJ; Jordan, MB; Kumar, AR; Grimley, MS; Krupski, C; Davies, SM; Khandelwal, P; et al. Journal of Clinical Immunology. 2021; 41:89-98.

Defective FAS-Mediated Apoptosis and Immune Dysregulation in Gaucher Disease. Miano, M; Madeo, A; Cappelli, E; Lanza, F; Lanza, T; Stroppiano, M; Terranova, P; Venè, R; Bleesing, JJ H; Di Rocco, M. Journal of Allergy and Clinical Immunology: In Practice. 2020; 8:3535-3542.

Successful Response to Treatment with Sirolimus in Pulmonary Sarcoidosis. Gupta, N; Bleesing, JH; McCormack, FX. American Journal of Respiratory and Critical Care Medicine. 2020; 202:e119-e120.

CCR5 inhibitor as novel acute graft versus host disease prophylaxis in children and young adults undergoing allogeneic stem cell transplant: results of the phase II study. Khandelwal, P; Fukuda, T; Teusink-Cross, A; Kashuba, AD M; Lane, A; Mehta, PA; Marsh, RA; Jordan, MB; Grimley, MS; Myers, KC; et al. Bone Marrow Transplantation. 2020; 55:1552-1559.