Rothenberg CURED Lab

Wen, T; Aronow, BJ; Rochman, Y; Rochman, M; Kiran, KC; Dexheimer, PJ; Putnam, P; Mukkada, V; Foote, H; Rehn, K; et al. Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. Journal of Clinical Investigation. 2019; 129:2014-2028.

Travers, J; Rochman, M; Miracle, CE; Habel, JE; Brusilovsky, M; Caldwell, JM; Rymer, JK; Rothenberg, ME. Chromatin regulates IL-33 release and extracellular cytokine activity. Nature Communications. 2018; 9.

Shoda, T; Wen, T; Aceves, SS; Abonia, JP; Atkins, D; Bonis, PA; Caldwell, JM; Capocelli, KE; Carpenter, CL; Collins, MH; et al. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. The Lancet Gastroenterology and Hepatology. 2018; 3:477-488.

Azouz, NP; Ynga-Durand, MA; Caldwell, JM; Jain, A; Rochman, M; Fischesser, DM; Ray, LM; Bedard, MC; Mingler, MK; Forney, C; et al. The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses. Science Translational Medicine. 2018; 10.

Martin, LJ; He, H; Collins, MH; Abonia, JP; Myers, JM B; Eby, M; Johansson, H; Kottyan, LC; Hershey, GK K; Rothenberg, ME. Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci. Journal of Allergy and Clinical Immunology. 2018; 141:1690-1698.

Caldwell, JM; Collins, MH; Kemme, KA; Sherrill, JD; Wen, T; Rochman, M; Stucke, EM; Amin, L; Tai, H; Putnam, PE; et al. Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation. Mucosal Immunology. 2017; 10:1190-1201.

Davis, BP; Stucke, EM; Khorki, ME; Litosh, VA; Rymer, JK; Rochman, M; Travers, J; Kottyan, LC; Rothenberg, ME. Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. JCI insight. 2016; 1.

Kottyan, LC; Davis, BP; Sherrill, JD; Liu, K; Rochman, M; Kaufman, K; Weirauch, MT; Vaughn, S; Lazaro, S; Rupert, AM; et al. Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. Nature Genetics. 2014; 46:895-900.

Wen, T; Stucke, EM; Grotjan, TM; Kemme, KA; Abonia, JP; Putnam, PE; Franciosi, JP; Garza, JM; Kaul, A; King, EC; et al. Molecular diagnosis of eosinophilic esophagitis by gene expression profiling. Gastroenterology. 2013; 145:1289-1299.

Collins, MH; Rothenberg, ME; Bredenoord, AJ; Wechsler, J; Chehade, M; Philpott, H; Chen, Z; Radwan, A; Pela, T; Khodzhayev, A; et al. 233. ENDOSCOPIC REFERENCE SCORE AND HISTOLOGICAL SCORING SYSTEM ARE COMPLEMENTARY ASSESSMENTS FOR CHARACTERIZING FIBROSTENOTIC OR INFLAMMATORY PHENOTYPES IN EOSINOPHILIC ESOPHAGITIS PATIENTS. Gullet. 2022; 35.

Hirano, I; Rothenberg, ME; Spergel, JM; Aceves, S; Greenhawt, M; Schoepfer, AM; Philpott, H; Chen, Z; Radwan, A; Khodzhayev, A; et al. 230. ENDOSCOPIC REFERENCE SCORE REMODELING SUBSCORE AND ESOPHAGEAL EOSINOPHIL COUNT DO NOT CORRELATE IN PLACEBO-TREATED EOSINOPHILIC ESOPHAGITIS PATIENTS FROM DUPILUMAB STUDIES. Gullet. 2022; 35.

Schreiner, P; Safroneeva, E; Schoepfer, A; Greuter, T; Biedermann, L; Schlag, C; Labenz, J; Auth, MK H; Bredenoord, AJ; Chang, JW; et al. Management of eosinophilic esophagitis associated food impaction in Europe and the United States. Diseases of the Esophagus. 2022; 35.

Avlas, S; Shani, G; Rhone, N; Itan, M; Dolitzky, A; Hazut, I; Grisaru-Tal, S; Gordon, Y; Shoda, T; Ballaban, A; et al. Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2022.

Rothenberg, ME; Roufosse, F; Faguer, S; Gleich, GJ; Steinfeld, J; Yancey, SW; Mavropoulou, E; Kwon, N; García, GR; Sosso, A; et al. Mepolizumab Reduces Hypereosinophilic Syndrome Flares Irrespective of Blood Eosinophil Count and Interleukin-5. Journal of Allergy and Clinical Immunology: In Practice. 2022; 10:2367-2374.e3.

Grisaru-Tal, S; Rothenberg, ME; Munitz, A. Eosinophil-lymphocyte interactions in the tumor microenvironment and cancer immunotherapy. Nature Immunology. 2022; 23:1309-1316.

Brusilovsky, M; Rochman, M; Shoda, T; Kotliar, M; Caldwell, JM; Mack, LE; Besse, JA; Chen, X; Weirauch, MT; Barski, A; et al. Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling. Gut. 2022.

McNaught, E; Treasure, J; Pollard, N. Overview. Eating Disorders. 2022.

Seibold, MA; Moore, CM; Everman, JL; Williams, BJ M; Nolin, JD; Fairbanks-Mahnke, A; Plender, EG; Patel, BB; Arbes, SJ; Bacharier, LB; et al. Risk factors for SARS-CoV-2 infection and transmission in households with children with asthma and allergy: A prospective surveillance study. Journal of Allergy and Clinical Immunology. 2022; 150:302-311.

Daniel, N; Larey, A; Aknin, E; Osswald, GA; Caldwell, JM; Rochman, M; Collins, MH; Yang, GY; Arva, NC; Capocelli, KE; et al. (2022) A Deep Multi-Label Segmentation Network For Eosinophilic Esophagitis Whole Slide Biopsy Diagnostics. 2022:3211-3217.

Fulkerson, PC; Lussier, SJ; Bendixsen, CG; Castina, SM; Gebretsadik, T; Marlin, JS; Russell, PB; Seibold, MA; Everman, JL; Moore, CM; et al. Human Epidemiology and RespOnse to SARS-CoV-2 (HEROS): Objectives, Design and Enrollment Results of a 12-City Remote Observational Surveillance Study of Households with Children using Direct-to-Participant Methods. 2022.

Droghini, HR; Abonia, JP; Collins, MH; Milner, JD; Lyons, JJ; Freeman, AF; Mukkada, VA; Risma, KA; Rothenberg, ME; Schwartz, JT. Targeted IL-4Rα blockade ameliorates refractory allergic eosinophilic inflammation in a patient with dysregulated TGF-β signaling due to ERBIN deficiency. Journal of Allergy and Clinical Immunology: In Practice. 2022; 10:1903-1906.

Dellon, ES; Khoury, P; Muir, AB; Liacouras, CA; Safroneeva, E; Atkins, D; Collins, MH; Gonsalves, N; Falk, GW; Spergel, JM; et al. A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions. Gastroenterology. 2022; 163:59-76.

Dellon, ES; Khoury, P; Muir, AB; Liacouras, CA; Safroneeva, E; Atkins, D; Collins, MH; Gonsalves, N; Falk, GW; Spergel, JM; et al. A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions. Journal of Allergy and Clinical Immunology. 2022; 150:33-47.

Tanzer, J; Meng, D; Ohsaki, A; Caldwell, JM; Mingler, MK; Rothenberg, ME; Oyoshi, MK. Laundry detergent promotes allergic skin inflammation and esophageal eosinophilia in mice. PLoS ONE. 2022; 17.

Rochman, M; Wen, T; Kotliar, M; Dexheimer, PJ; Morgenstern, NB B; Caldwell, JM; Lim, HW; Rothenberg, ME. Single-cell RNA-Seq of human esophageal epithelium in homeostasis and allergic inflammation. JCI insight. 2022; 7.

Zhang, S; Shoda, T; Aceves, SS; Arva, NC; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Gonsalves, N; Gupta, SK; et al. Mast cell-pain connection in eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2022; 77:1895-1899.

Ben-Baruch Morgenstern, N; Ballaban, AY; Wen, T; Shoda, T; Caldwell, JM; Kliewer, K; Felton, JM; Abonia, JP; Mukkada, VA; Putnam, PE; et al. Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission. Journal of Allergy and Clinical Immunology. 2022; 149:2062-2077.

Eapen, AA; Parameswaran, S; Forney, C; Edsall, LE; Miller, D; Donmez, O; Dunn, K; Lu, X; Granitto, M; Rowden, H; et al. Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis. PLoS Genetics. 2022; 18.

Shoda, T; Collins, MH; Rochman, M; Wen, T; Caldwell, JM; Mack, LE; Osswald, GA; Besse, JA; Haberman, Y; Aceves, SS; et al. Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022; 162:1635-1649.

Chen, MM; Roufosse, F; Wang, SA; Verstovsek, S; Durrani, SR; Rothenberg, ME; Pongdee, T; Butterfield, J; Lax, T; Wechsler, ME; et al. An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinophilic Syndromes. Journal of Allergy and Clinical Immunology: In Practice. 2022; 10:1217-1228.e3.

Rothenberg, ME. The climate change hypothesis for the allergy epidemic. Journal of Allergy and Clinical Immunology. 2022; 149:1522-1524.

Ziv, YH; Collins, MH; Gonsalves, N; Katzka, DA; Rothenberg, ME. Eosinophilic esophagitis. Yamada's Atlas of Gastroenterology. 2022.

Safroneeva, E; Pan, Z; King, E; Martin, LJ; Collins, MH; Yang, GY; Capocelli, KE; Arva, NC; Abonia, JP; Atkins, D; et al. Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms After Dilation in Adults With Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2022; 20:766-775.e4.

Robida, PA; Rische, CH; Morgenstern, NB B; Janarthanam, R; Cao, Y; Krier-Burris, RA; Korver, W; Xu, A; Luu, T; Schanin, J; et al. Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells. Cells. 2022; 11.

Dellon, ES; Gonsalves, N; Rothenberg, ME; Hirano, I; Chehade, M; Peterson, KA; Falk, GW; Murray, JA; Gehman, LT; Chang, AT; et al. Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab. Clinical Gastroenterology and Hepatology. 2022; 20:535-545.e15.

Collins, MH; Alexander, ES; Martin, LJ; Grotjan, TM; Mukkada, VA; Sheil, A; Abonia, JP; Putnam, PE; Rothenberg, ME. Acquired Esophageal Strictures in Children: Morphometric and Immunohistochemical Analyses. Pediatric and Developmental Pathology. 2022; 25:124-133.

Rothenberg, ME; Hottinger, SK B; Gonsalves, N; Furuta, GT; Collins, MH; Talley, NJ; Peterson, K; Menard-Katcher, C; Smith, M; Hirano, I; et al. Impressions and aspirations from the FDA GREAT VI Workshop on Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis and Perspectives for Progress in the Field. Journal of Allergy and Clinical Immunology. 2022; 149:844-853.

Hirano, I; Collins, MH; King, E; Sun, Q; Chehade, M; Abonia, JP; Bonis, PA; Capocelli, KE; Dellon, ES; Falk, GW; et al. Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort. American Journal of Gastroenterology. 2022; 117:413-423.

Dellon, ES; Gonsalves, N; Abonia, JP; Alexander, JA; Arva, NC; Atkins, D; Attwood, SE; Auth, MK H; Bailey, DD; Biederman, L; et al. International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature. Clinical Gastroenterology and Hepatology. 2022.

Ma, C; Schoepfer, AM; Dellon, ES; Bredenoord, AJ; Chehade, M; Collins, MH; Feagan, BG; Furuta, GT; Gupta, SK; Hirano, I; et al. Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS). Journal of Allergy and Clinical Immunology. 2022; 149:659-670.

Min, S; Shoda, T; Wen, T; Rothenberg, ME. Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy. Journal of Allergy and Clinical Immunology. 2022; 149:782-787.e1.

Brusilovsky, M; Bao, R; Rochman, M; Kemter, AM; Nagler, CR; Rothenberg, ME. Host-Microbiota Interactions in the Esophagus During Homeostasis and Allergic Inflammation. Gastroenterology. 2022; 162:521-534.e8.

Shoda, T; Wen, T; Caldwell, JM; Ben-Baruch Morgenstern, N; Osswald, GA; Rochman, M; Mack, LE; Felton, JM; Abonia, JP; Arva, NC; et al. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022; 162:439-453.

Dunn, JL M; Rothenberg, ME. 2021 year in review: Spotlight on eosinophils. Journal of Allergy and Clinical Immunology. 2022; 149:517-524.

Hiremath, G; Sun, L; Correa, H; Acra, S; Collins, MH; Bonis, P; Arva, NC; Capocelli, KE; Falk, GW; King, E; et al. Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis. American Journal of Gastroenterology. 2022; 117:272-279.

Rothenberg, ME. Linking the allergy epidemic to climate change. Nature Immunology. 2022; 23.

Gleich, GJ; Roufosse, F; Chupp, G; Faguer, S; Walz, B; Reiter, A; Yancey, SW; Bentley, JH; Steinfeld, J; García, GR; et al. Safety and Efficacy of Mepolizumab in Hypereosinophilic Syndrome: An Open-Label Extension Study. Journal of Allergy and Clinical Immunology: In Practice. 2021; 9:4431-4440.e1.

Shoda, T; Kaufman, KM; Wen, T; Caldwell, JM; Osswald, GA; Purnima, P; Zimmermann, N; Collins, MH; Rehn, K; Foote, H; et al. Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis. Nature Communications. 2021; 12.

Fox-Fisher, I; Piyanzin, S; Ochana, BL; Klochendler, A; Magenheim, J; Peretz, A; Loyfer, N; Moss, J; Cohen, D; Drori, Y; et al. Remote immune processes revealed by immune-derived circulating cell-free DNA. eLife. 2021; 10.

Felton, JM; Bouffi, C; Schwartz, JT; Schollaert, KL; Malik, A; Vallabh, S; Wronowski, B; Magier, AZ; Merlin, L; Barski, A; et al. Aiolos regulates eosinophil migration into tissues. Mucosal Immunology. 2021; 14:1271-1281.

Grisaru-Tal, S; Dulberg, S; Beck, L; Zhang, C; Itan, M; Hediyeh-Zadeh, S; Caldwell, J; Rozenberg, P; Dolitzky, A; Avlas, S; et al. Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity. Cancer Research. 2021; 81:5555-5571.

Mahoney, M; Damalanka, VC; Tartell, MA; Chung, DH; Lourenço, AL; Pwee, D; Mayer Bridwell, AE; Hoffmann, M; Voss, J; Karmakar, P; et al. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proceedings of the National Academy of Sciences of the United States of America. 2021; 118.

Jin, K; Bardes, EE; Mitelpunkt, A; Wang, JY; Bhatnagar, S; Sengupta, S; Krummel, DP; Rothenberg, ME; Aronow, BJ. An interactive single cell web portal identifies gene and cell networks in COVID-19 host responses. iScience. 2021; 24.

Brusilovsky, M; Rochman, M; Rochman, Y; Caldwell, JM; Mack, LE; Felton, JM; Habel, JE; Porollo, A; Pasare, C; Rothenberg, ME. Environmental allergens trigger type 2 inflammation through ripoptosome activation. Nature Immunology. 2021; 22:1316-1326.

Hiremath, G; Krischer, JP; Rothenberg, ME; Dellon, ES. Validation of self-reported diagnosis of eosinophilic gastrointestinal disorders patients enrolled in the CEGIR contact registry. Gastroenterologie Clinique et Biologique. 2021; 45.

Dunn, JL M; Caldwell, JM; Ballaban, A; Ben-Baruch Morgenstern, N; Rochman, M; Rothenberg, ME. Bidirectional crosstalk between eosinophils and esophageal epithelial cells regulates inflammatory and remodeling processes. Mucosal Immunology. 2021; 14:1133-1143.

Ma, C; Schoepfer, AM; Safroneeva, E; Dellon, ES; Bredenoord, AJ; Chehade, M; Collins, MH; Feagan, BG; Furuta, GT; Gupta, SK; et al. Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus. Gastroenterology. 2021; 161:748-755.

Friedlander, JA; Fleischer, DM; Black, JO; Levy, M; Rothenberg, ME; Smith, C; Nguyen, N; Pan, Z; Furuta, GT. Unsedated transnasal esophagoscopy with virtual reality distraction enables earlier monitoring of dietary therapy in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology: In Practice. 2021; 9:3494-3496.

Ma, C; Schoepfer, AM; Safroneeva, E; Dellon, ES; Bredenoord, AJ; Chehade, M; Collins, MH; Feagan, BG; Furuta, GT; Gupta, SK; et al. (2021) A Summary of the Meetings of the Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS) International Multidisciplinary Consensus. 161:778-784.

Felton, JM; Vallabh, S; Parameswaran, S; Edsall, LE; Ernst, K; Wronowski, B; Malik, A; Kotliar, M; Weirauch, MT; Barski, A; et al. Epigenetic Analysis of the Chromatin Landscape Identifies a Repertoire of Murine Eosinophil-Specific PU.1-Bound Enhancers. Journal of Immunology. 2021; 207:1044-1054.

Morgenstern, NB B; Rochman, M; Rothenberg, ME. Zooming in on T cell clones: Are we heading to personalized treatment of allergy?. Science Immunology. 2021; 6.

Czyzewski, T; Daniel, N; Rochman, M; Caldwell, J; Osswald, G; Collins, M; Rothenberg, M; Savir, Y. Machine Learning Approach for Biopsy-Based Identification of Eosinophilic Esophagitis Reveals Importance of Global features. IEEE Open Journal of Engineering in Medicine and Biology. 2021; 2:218-223.

Jin, K; Bardes, EE; Mitelpunkt, A; Wang, JY; Bhatnagar, S; Sengupta, S; Krummel, DP; Rothenberg, ME; Aronow, BJ. Implicating Gene and Cell Networks Responsible for Differential COVID-19 Host Responses via an Interactive Single Cell Web Portal. 2021.

Rothenberg, ME. An Allergic Basis for Abdominal Pain. New England Journal of Medicine. 2021; 384:2156-2158.

Sabet, C; Klion, AD; Bailey, D; Jensen, E; Chehade, M; Abonia, JP; Rothenberg, ME; Furuta, GT; Muir, AB. Do rural health disparities affect prevalence data in pediatric eosinophilic esophagitis?. Journal of Allergy and Clinical Immunology: In Practice. 2021; 9:2549-2551.

Rochman, M; Xie, YM; Mack, L; Caldwell, JM; Klingler, AM; Osswald, GA; Azouz, NP; Rothenberg, ME. Broad transcriptional response of the human esophageal epithelium to proton pump inhibitors. Journal of Allergy and Clinical Immunology. 2021; 147:1924-1935.

Chiang, AW T; Duong, LD; Shoda, T; Nhu, QM; Ruffner, M; Hara, T; Aaron, B; Joplin, E; Manresa, MC; Abonia, JP; et al. Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:718-722.

Jacobsen, EA; Jackson, DJ; Heffler, E; Mathur, SK; Bredenoord, AJ; Pavord, ID; Akuthota, P; Roufosse, F; Rothenberg, ME. Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies. Annual Review of Immunology. 2021; 39:719-757.

Azouz, NP; Klingler, AM; Callahan, V; Akhrymuk, IV; Elez, K; Raich, L; Henry, BM; Benoit, JL; Benoit, SW; Noé, F; et al. Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. Pathogens and Immunity. 2021; 6:55-74.

Mersha, TB; Afanador, Y; Johansson, E; Proper, SP; Bernstein, JA; Rothenberg, ME; Hershey, GK K. Resolving Clinical Phenotypes into Endotypes in Allergy: Molecular and Omics Approaches. Clinical Reviews in Allergy and Immunology. 2021; 60:200-219.

Dellon, ES; Collins, MH; Rothenberg, ME; Assouline-Dayan, Y; Evans, L; Gupta, S; Schoepfer, A; Straumann, A; Safroneeva, E; Rodriguez, C; et al. Long-term Efficacy and Tolerability of RPC4046 in an Open-Label Extension Trial of Patients With Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2021; 19:473-483.e17.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2021; 147:851-852.

Dellon, ES; Shaheen, O; Koutlas, NT; Chang, AO; Martin, LJ; Rothenberg, ME; Jensen, ET. Early life factors are associated with risk for eosinophilic esophagitis diagnosed in adulthood. Diseases of the Esophagus. 2021; 34.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2021; 147:490-491.

Hempel, T; Raich, L; Olsson, S; Azouz, NP; Klingler, AM; Hoffmann, M; Pöhlmann, S; Rothenberg, ME; Noé, F. Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat. Chemical Science. 2021; 12:983-992.

Czyzewski, T; Daniel, N; Rochman, M; Caldwell, J; Osswald, G; Collins, M; Rothenberg, M; Savir, Y. Machine learning approach for biopsy-based identification of eosinophilic esophagitis reveals importance of global features. 2021.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2021; 147:43-44.

O'Shea, KM; Rochman, M; Shoda, T; Zimmermann, N; Caldwell, J; Rothenberg, ME. Eosinophilic esophagitis with extremely high esophageal eosinophil counts. Journal of Allergy and Clinical Immunology. 2021; 147:409-412.e5.

Kottyan, LC; Trimarchi, MP; Lu, X; Caldwell, JM; Maddox, A; Parameswaran, S; Lape, M; D'Mello, RJ; Bonfield, M; Ballaban, A; et al. Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes. Journal of Allergy and Clinical Immunology. 2021; 147:255-266.

Lyles, JL; Martin, LJ; Shoda, T; Collins, MH; Trimarchi, MP; He, H; Kottyan, LC; Mukkada, VA; Rothenberg, ME. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. Journal of Allergy and Clinical Immunology. 2021; 147:244-254.e6.

Roufosse, F; Kahn, JE; Rothenberg, ME; Wardlaw, AJ; Klion, AD; Kirby, SY; Gilson, MJ; Bentley, JH; Bradford, ES; Yancey, SW; et al. Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial. Journal of Allergy and Clinical Immunology. 2020; 146:1397-1405.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:1341-1342.

Rothenberg, ME. Transferring allergies in the womb. Science. 2020; 370:907-908.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:993-994.

Dellon, ES; Peterson, KA; Murray, JA; Falk, GW; Gonsalves, N; Chehade, M; Genta, RM; Leung, J; Khoury, P; Klion, AD; et al. Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis. New England Journal of Medicine. 2020; 383:1624-1634.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:774-775.

Ben Baruch-Morgenstern, N; Rochman, M; Rothenberg, ME. Pumping mast cells out of allergic inflammation-are proton pump inhibitors taking center stage?. Journal of Allergy and Clinical Immunology. 2020; 146:783-785.

Jensen, ET; Aceves, SS; Bonis, PA; Bray, K; Book, W; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Gonsalves, N; et al. High Patient Disease Burden in a Cross-sectional, Multicenter Contact Registry Study of Eosinophilic Gastrointestinal Diseases. Journal of Pediatric Gastroenterology and Nutrition. 2020; 71:524-529.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:507-508.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:256-257.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:50-51.

Pesek, RD; Reed, CC; Collins, MH; Muir, AB; Fulkerson, PC; Menard-Katcher, C; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; et al. Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. Digestive Diseases and Sciences. 2020; 65:2024-2035.

Lindsley, AW; Schwartz, JT; Rothenberg, ME. Eosinophil responses during COVID-19 infections and coronavirus vaccination. Journal of Allergy and Clinical Immunology. 2020; 146:1-7.

Brusilovsky, M; Rochman, M; Azouz, NP; Mack, LE; Rothenberg, ME. Uncovering the secretes of allergic inflammation. Journal of Clinical Investigation. 2020; 130:3419-3421.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:1549-1550.

Dunn, JL M; Shoda, T; Caldwell, JM; Wen, T; Aceves, SS; Collins, MH; Dellon, ES; Falk, GW; Leung, J; Martin, LJ; et al. Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort. Journal of Allergy and Clinical Immunology. 2020; 145:1629-1640.e4.

Bousquet, J; Rothenberg, M. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:1549-1550.

Azouz, NP; Klingler, AM; Pathre, P; Besse, JA; Ben Baruch-Morgenstern, N; Ballaban, AY; Osswald, GA; Brusilovsky, M; Habel, JE; Caldwell, JM; et al. Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis. Science Translational Medicine. 2020; 12.

Collins, MH; Martin, LJ; Wen, T; Abonia, JP; Putnam, PE; Mukkada, VA; Rothenberg, ME. Eosinophilic Esophagitis Histology Remission Score: Significant Relations to Measures of Disease Activity and Symptoms. Journal of Pediatric Gastroenterology and Nutrition. 2020; 70:598-603.

Safroneeva, E; Aceves, SS; King, E; Sun, Q; Collins, MH; Yang, G; Capocelli, K; Arva, N; Abonia, JP; Atkins, D; et al. Mo1187 DILATION REDUCES POSITIVE CORRELATION BETWEEN SYMPTOMS AND HISTOLOGIC FINDINGS IN ADULTS WITH EOSINOPHILIC ESOPHAGITIS. Gastroenterology. 2020; 158:s-819.

Dellon, ES; Peterson, KA; Murray, JA; Falk, GW; Gonsalves, N; Chehade, M; Leung, J; Genta, RM; Rothenberg, ME; Khoury, P; et al. 932 HISTOLOGIC AND SYMPTOMATIC IMPROVEMENT ACROSS MULTIPLE FORMS OF EOSINOPHILIC GASTROINTESTINAL DISEASES IN ENIGMA, A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ANTOLIMAB (AK002). Gastroenterology. 2020; 158:s-186.

Gupta, SK; Pesek, R; Wang, Y; Foss, K; Bonis, PA; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Furuta, G; et al. Su1001 CLINICAL CHARACTERISTICS AND DISEASE FEATURES FROM A MULTICENTER LONGITUDINAL COHORT OF EOSINOPHILIC GASTROINTESTINAL DISORDERS MAY INFORM FUTURE STUDIES. Gastroenterology. 2020; 158:s-493.

Hamilton, JD; Lim, WK; Hamon, SC; Rothenberg, ME; Collins, MH; Chehade, M; Harel, S; Wipperman, MF; Hirano, I; Dellon, ES; et al. Mo1228 DUPILUMAB NORMALIZES THE EOSINOPHILIC ESOPHAGITIS DISEASE TRANSCRIPTOME IN ADULT PATIENTS WITH EOSINOPHILIC ESOPHAGITIS. Gastroenterology. 2020; 158:s-835.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:1350-1351.

Oliva, S; Azouz, NP; Stronati, L; Rothenberg, ME. Recent advances in potential targets for eosinophilic esophagitis treatments. Expert Review of Clinical Immunology. 2020; 16:421-428.

Henderson, A; Magier, A; Schwartz, JT; Martin, LJ; Collins, MH; Putnam, PE; Mukkada, VA; Abonia, JP; Rothenberg, ME; Fulkerson, PC. Monitoring Eosinophilic Esophagitis Disease Activity With Blood Eosinophil Progenitor Levels. Journal of Pediatric Gastroenterology and Nutrition. 2020; 70:482-488.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:1134-1135.

Applequist, J; Burroughs, C; Jr, RA; Merkel, PA; Rothenberg, ME; Trapnell, B; Desnick, RJ; Sahin, M; Krischer, JP. A novel approach to conducting clinical trials in the community setting: utilizing patient-driven platforms and social media to drive web-based patient recruitment. BMC Medical Research Methodology. 2020; 20.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:771-772.

Bitton, A; Avlas, S; Reichman, H; Itan, M; Karo-Atar, D; Azouz, NP; Rozenberg, P; Diesendruck, Y; Nahary, L; Rothenberg, ME; et al. A key role for IL-13 signaling via the type 2 IL-4 receptor in experimental atopic dermatitis. Science Immunology. 2020; 5.

Mersha, T; Gautam, Y; Caldwell, J; Rothenberg, M. Genome-wide admixture and association analyses identify novel eosinophilic esophagitis-associated loci in African American ancestry. Journal of Allergy and Clinical Immunology. 2020; 145.

Avlas, S; Itan, M; Dolitzky, A; Varol, C; Rothenberg, M; Munitz, A. Intraesophageal administration of oxazolone to skin-sensitized mice results in experimental eosinophilic esophagitis‏ ‏resembling human disease. Journal of Allergy and Clinical Immunology. 2020; 145.

Munitz, A; Bitton, A; Avlas, S; Reichman, H; Itan, M; Karo-Atar, D; Azouz, N; Rozenberg, P; Nahari, L; Rothenberg, M; et al. A key role for IL-13 signaling via the type 2 IL-4 receptor in atopic dermatitis. Journal of Allergy and Clinical Immunology. 2020; 145.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:474-475.

Hirano, I; Dellon, ES; Hamilton, JD; Collins, MH; Peterson, K; Chehade, M; Schoepfer, AM; Safroneeva, E; Rothenberg, ME; Falk, GW; et al. Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis. Gastroenterology. 2020; 158:111-122.e10.

Vanoni, S; Zeng, C; Marella, S; Uddin, J; Wu, D; Arora, K; Ptaschinski, C; Que, J; Noah, T; Waggoner, L; et al. Identification of anoctamin 1 (ANO1) as a key driver of esophageal epithelial proliferation in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2020; 145:239-254.e2.

Pesek, RD; Rothenberg, ME. Eosinophilic gastrointestinal disease below the belt. Journal of Allergy and Clinical Immunology. 2020; 145:87-89.e1.

Shoda, T; Wen, T; Caldwell, JM; Collins, MH; Besse, JA; Osswald, GA; Abonia, JP; Arva, NC; MDd, DA; Capocelli, KE; et al. Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. Journal of Allergy and Clinical Immunology. 2020; 145:255-269.

Aceves, S; Collins, MH; Rothenberg, ME; Furuta, GT; Gonsalves, N; Abonia, JP; Almonte, S; Andrews, R; Arrington, A; Arva, N; et al. Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Journal of Allergy and Clinical Immunology. 2020; 145:28-37.

Kottyan, LC; Parameswaran, S; Weirauch, MT; Rothenberg, ME; Martin, LJ. The genetic etiology of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2020; 145:9-15.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:85-86.

Kurten, RC; Rawson, R; Shoda, T; Duong, LD; Adejumobi, D; Levy, R; Newbury, RO; Rothenberg, ME; Akuthota, P; Wright, BL; et al. Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. Scientific Reports. 2019; 9.

Klion, AD; Rothenberg, ME. Advances in eosinophilic diseases in 2018. Journal of Allergy and Clinical Immunology. 2019; 144:1490-1494.

Rothenberg, ME; Bousquet, J. News beyond our pages. Journal of Allergy and Clinical Immunology. 2019; 144:1511-1512.

Doucet-Ladeveze, R; Holvoet, S; Raymond, F; Foata, F; Hershey, GK K; Sherrill, JD; Rothenberg, ME; Blanchard, C. Transcriptomic Analysis Links Eosinophilic Esophagitis and Atopic Dermatitis. Frontiers in Pediatrics. 2019; 7.

Wen, T; Rothenberg, ME. Cell-by-cell deciphering of T cells in allergic inflammation. Journal of Allergy and Clinical Immunology. 2019; 144:1143-1148.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:1156-1157.

Lyles, J; Rothenberg, M. Role of genetics, environment, and their interactions in the pathogenesis of eosinophilic esophagitis. Current Opinion in Immunology. 2019; 60:46-53.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:924-925.

Muir, AB; Jensen, ET; Wechsler, JB; Menard-Katcher, P; Falk, GW; Aceves, SS; Furuta, GT; Dellon, ES; Rothenberg, ME; Spergel, JM. Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. Journal of Allergy and Clinical Immunology: In Practice. 2019; 7:2434-2436.

Rothenberg, ME; Bousquet, J. News beyond our pages. Journal of Allergy and Clinical Immunology. 2019; 144:643-644.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:395-396.

Ben Baruch-Morgenstern, N; Shoda, T; Rothenberg, ME. Bagels and LOX in patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2019; 144:41-43.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:36-37.

Wheeler, JC; Vanoni, S; Zeng, C; Waggoner, L; Yang, Y; Wu, D; Uddin, J; Karns, R; Kottyan, L; Mukkada, V; et al. 17β-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling. Journal of Allergy and Clinical Immunology. 2019; 143:2131-2146.

Pesek, RD; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, C; Falk, GW; Kuhl, J; Martin, EK; Magier, AZ; Ahmed, F; et al. Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium. American Journal of Gastroenterology. 2019; 114:984-994.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:2009-2010.

DiTommaso, LA; Rosenberg, CE; Eby, MD; Tasco, A; Collins, MH; Lyles, JL; Putnam, PE; Mukkada, VA; Rothenberg, ME. Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia. Journal of Allergy and Clinical Immunology. 2019; 143:1928-1930.e3.

Wen, T; Aronow, BJ; Rochman, Y; Rochman, M; Kiran, KC; Dexheimer, PJ; Putnam, P; Mukkada, V; Foote, H; Rehn, K; et al. Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. Journal of Clinical Investigation. 2019; 129:2014-2028.

Jensen, ET; Abonia, JP; Aceves, SS; Bonis, PA; Bray, K; Book, WM; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; et al. Mo1133 – High Patient-Reported Disease Burden for Eosinophilic Gastrointestinal Disorders. Gastroenterology. 2019; 156:s-717.

Dellon, ES; Peterson, KA; Genta, RM; Murray, JA; Gonsalves, N; Chehade, M; Rothenberg, ME; Khoury, P; Bledsoe, AC; Singh, B; et al. Mo1127 – Mast Cells in Addition to Eosinophils are Markedly Elevated At Baseline in Patients with Eosinophilic Gastritis And/Or Gastroenteritis. Gastroenterology. 2019; 156:s-714.

Kliewer, K; Aceves, SS; Atkins, D; Bonis, PA; Chehade, M; Collins, MH; Dellon, ES; Fei, L; Gupta, SK; Kagalwalla, AF; et al. 817 – Efficacy of 1-Food and 4-Food Elimination Diets for Pediatric Eosinophilic Esophagitis in a Randomized Multi-Site Study. Gastroenterology. 2019; 156.

Muir, AB; Jensen, ET; Wechsler, JB; Menard-Katcher, P; Aceves, SS; Falk, GW; Furuta, G; Dellon, ES; Rothenberg, ME; Spergel, J. Su1754 – Overestimation of the Prevalence of Eosinophilic Colitis with Reliance on a Single Billing Code. Gastroenterology. 2019; 156:s-605.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:1729-1730.

Kottyan, LC; Maddox, A; Braxton, JR; Stucke, EM; Mukkada, V; Putnam, PE; Abonia, JP; Chehade, M; Wood, RA; Pesek, RD; et al. Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Genes and Immunity. 2019; 20:281-292.

Krishnan, U; Lijuan, C; Andrew, GJ; Rothenberg, ME; Wen, T. Analysis of eosinophilic esophagitis in children with repaired congenital esophageal atresia. Journal of Allergy and Clinical Immunology. 2019; 143:1455-1464.e2.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:1334-1335.

Azouz, NP; Rothenberg, ME. Mechanisms of gastrointestinal allergic disorders. Journal of Clinical Investigation. 2019; 129:1419-1430.

Miller, DE; Forney, C; Rochman, M; Cranert, S; Habel, J; Rymer, J; Lynch, A; Schroeder, C; Lee, J; Sauder, A; et al. Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14. G3: Genes, Genomes, Genetics. 2019; 9:729-736.

Schwartz, JT; Morris, DW; Collins, MH; Rothenberg, ME; Fulkerson, PC. Eosinophil progenitor levels correlate with tissue pathology in pediatric eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2019; 143:1221-1224.e3.

Gupta, SK; Falk, GW; Aceves, SS; Chehade, M; Collins, MH; Dellon, ES; Gonsalves, N; Hirano, I; Mukkuda, VA; Peterson, KA; et al. Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration. Gastroenterology. 2019; 156:838-842.

Miller, DE; Forney, C; Rochman, M; Cranert, S; Habel, J; Rymer, J; Lynch, A; Schroeder, C; Lee, J; Sauder, A; et al. Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14. G3: Genes, Genomes, Genetics. 2019; 9:729-736.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:921-922.

Hirano, I; Collins, MH; Assouline-Dayan, Y; Evans, L; Gupta, S; Schoepfer, AM; Straumann, A; Safroneeva, E; Grimm, M; Smith, H; et al. RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis. Gastroenterology. 2019; 156:592-603.e10.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:540-541.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:76-77.

Ghosh, D; Bernstein, JA; Hershey, GK K; Rothenberg, ME; Mersha, TB. Leveraging Multilayered "Omics " Data for Atopic Dermatitis: A Road Map to Precision Medicine. Frontiers in Immunology. 2018; 9.

Zeng, C; Vanoni, S; Wu, D; Caldwell, JM; Wheeler, JC; Arora, K; Noah, TK; Waggoner, L; Besse, JA; Yamani, AN; et al. Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 142:1843-1855.

Travers, J; Rochman, M; Miracle, CE; Habel, JE; Brusilovsky, M; Caldwell, JM; Rymer, JK; Rothenberg, ME. Chromatin regulates IL-33 release and extracellular cytokine activity. Nature Communications. 2018; 9.

Syed, M; Ball, JP; Mathis, KW; Hall, ME; Ryan, MJ; Rothenberg, ME; Cardozo, LL Y; Romero, DG. MicroRNA-21 ablation exacerbates aldosterone-mediated cardiac injury, remodeling, and dysfunction. American Journal of Physiology - Endocrinology and Metabolism. 2018; 315:E1154-E1167.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:1750-1751.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:1439-1440.

Trisno, SL; Philo, KE D; McCracken, KW; Cata, EM; Ruiz-Torres, S; Rankin, SA; Han, L; Nasr, T; Chaturvedi, P; Rothenberg, ME; et al. Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification. Cell Stem Cell. 2018; 23:501-515.e7.

Hiremath, G; Kodroff, E; Strobel, MJ; Scott, M; Book, W; Reidy, C; Kyle, S; Mack, D; Sable, K; Abonia, P; et al. Individuals affected by eosinophilic gastrointestinal disorders have complex unmet needs and frequently experience unique barriers to care. Gastroenterologie Clinique et Biologique. 2018; 42:483-493.

Dellon, ES; Liacouras, CA; Molina-Infante, J; Furuta, GT; Spergel, JM; Zevit, N; Spechler, SJ; Attwood, SE; Straumann, A; Aceves, SS; et al. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. 2018; 155:1022-1033.e10.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:1054-1055.

Rosenberg, CE; Mingler, MK; Caldwell, JM; Collins, MH; Fulkerson, PC; Morris, DW; Mukkada, VA; Putnam, PE; Shoda, T; Wen, T; et al. Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2018; 73:1892-1901.

Chehade, M; Jones, SM; Pesek, RD; Burks, AW; Vickery, BP; Wood, RA; Leung, DY M; Furuta, GT; Fleischer, DM; Henning, AK; et al. Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research. Journal of Allergy and Clinical Immunology: In Practice. 2018; 6:1534-1544.e5.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:785-786.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:396-397.

Peinhaupt, M; Roula, D; Theiler, A; Sedej, M; Schicho, R; Marsche, G; Sturm, EM; Sabroe, I; Rothenberg, ME; Heinemann, A. DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator. Journal of Leukocyte Biology. 2018; 104:159-171.

Khoury, P; Akuthota, P; Ackerman, SJ; Arron, JR; Bochner, BS; Collins, MH; Kahn, J; Fulkerson, PC; Gleich, GJ; Gopal-Srivastava, R; et al. Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of Leukocyte Biology. 2018; 104:69-83.

Shoda, T; Wen, T; Aceves, SS; Abonia, JP; Atkins, D; Bonis, PA; Caldwell, JM; Capocelli, KE; Carpenter, CL; Collins, MH; et al. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. The Lancet Gastroenterology and Hepatology. 2018; 3:477-488.

Spergel, JM; Aceves, SS; Kliewer, K; Gonsalves, N; Chehade, M; Wechsler, JB; Groetch, M; Friedlander, J; Dellon, ES; Book, W; et al. New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting. Journal of Allergy and Clinical Immunology. 2018; 142:48-53.

Aceves, SS; King, E; Collins, MH; Yang, G; Capocelli, KE; Abonia, JP; Atkins, D; Bonis, PA; Carpenter, CL; Dellon, ES; et al. Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites. Journal of Allergy and Clinical Immunology. 2018; 142:130-138.e1.

Rochman, M; Azouz, NP; Rothenberg, ME. Epithelial origin of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 142:10-23.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:62-63.

Azouz, NP; Ynga-Durand, MA; Caldwell, JM; Jain, A; Rochman, M; Fischesser, DM; Ray, LM; Bedard, MC; Mingler, MK; Forney, C; et al. The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses. Science Translational Medicine. 2018; 10.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:2017-2018.

Lynch, MK; Barnes, MJ; Dimmitt, RA; Martin, L; Rothenberg, ME; Goodin, BR. Disease-Related Predictors of Health-Related Quality of Life in Youth With Eosinophilic Esophagitis. Journal of Pediatric Psychology. 2018; 43:464-471.

Martin, LJ; He, H; Collins, MH; Abonia, JP; Myers, JM B; Eby, M; Johansson, H; Kottyan, LC; Hershey, GK K; Rothenberg, ME. Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci. Journal of Allergy and Clinical Immunology. 2018; 141:1690-1698.

Collins, MH; Hirano, I; Dellon, ES; Peterson, KA; Chehade, M; Schoepfer, AM; Safroneeva, E; Rothenberg, ME; Falk, GW; Assouline-Dayan, Y; et al. Sa1151 - Baseline Characteristics and Correlation Between Dysphagia and Disease Activity in Patients with Eosinophilic Esophagitis in a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial. Gastroenterology. 2018; 154:s-259.

Reed, CC; Pesek, R; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Ahmed, FN; DeMarshall, M; Carpenter, C; et al. Sa1123 - Histologic Characterization of a Multi-Center Retrospective Cohort of Patients with Eosinophilic Gastrointestinal Disorders. Gastroenterology. 2018; 154.

Dellon, ES; Collins, MH; Assouline-Dayan, Y; Evans, L; Gupta, SK; Schoepfer, AM; Straumann, A; Safroneeva, E; Woo, A; Opiteck, G; et al. Sa1114 - Efficacy and Safety of Rpc4046, an Anti-Interleukin-13 Monoclonal Antibody, in Patients with Active Eosinophilic Esophagitis: Analysis of the Steroid-Refractory Subgroup from the Heroes Study. Gastroenterology. 2018; 154:s-244.

Pesek, R; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; DeMarshall, M; et al. Sa1117 - Treatment Patterns for Eosinophilic Gastritis, Enteritis and Colitis Vary Across Sites and Patient Age in a Multi-Center Consortium. Gastroenterology. 2018; 154.

Hirano, I; Collins, MH; Dellon, ES; Rothenberg, ME; Schoepfer, AM; Chehade, M; Chen, Z; Mannent, L; Graham, NM; Pirozzi, G; et al. Sa1112 - Endoscopic Features are Significantly Associated with Histologic Measures of Disease Activity in Patients with Active Eosinophilic Esophagitis: A Post HOC Analysis of a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial. Gastroenterology. 2018; 154.

Hirano, I; Hamilton, JD; Collins, MH; Lin, Z; Dellon, ES; Chen, Z; Peterson, KA; Chehade, M; Schoepfer, AM; Safroneeva, E; et al. Sa1113 - Correlation Between Esophageal Distensibility and Objective Measures of Disease in Patients with Active Eosinophilic Esophagitis: A Post HOC Analysis of a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial. Gastroenterology. 2018; 154:s-244.

Pesek, R; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; DeMarshall, M; et al. Sa1116 - Demographic Features of Eosinophilic Gastritis, Enteritis and Colitis Using 10 Years of Retrospective Data from a Multi-Center Consortium. Gastroenterology. 2018; 154:s-245.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:1580-1581.

Fulkerson, PC; Rothenberg, ME. Eosinophil Development, Disease Involvement, and Therapeutic Suppression. Advances in Immunology. 2018; 138:1-34.

Sherrill, JD; Kiran, KC; Wang, X; Wen, T; Chamberlin, A; Stucke, EM; Collins, MH; Abonia, JP; Peng, Y; Wu, Q; et al. Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis. JCI insight. 2018; 3.

Lu, TX; Rothenberg, ME. MicroRNA. Journal of Allergy and Clinical Immunology. 2018; 141:1202-1207.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:1210-1211.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:874-875.

Takemura, N; Kurashima, Y; Mori, Y; Okada, K; Ogino, T; Osawa, H; Matsuno, H; Aayam, L; Kaneto, S; Park, EJ; et al. Eosinophil depletion suppresses radiation-induced small intestinal fibrosis. Science Translational Medicine. 2018; 10.

Jensen, ET; Kuhl, JT; Martin, LJ; Langefeld, CD; Dellon, ES; Rothenberg, ME. Early-life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 141:632-637.e5.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:520-521.

Jensen, ET; Kuhl, JT; Martin, LJ; Rothenberg, ME; Dellon, ES. Prenatal, intrapartum, and postnatal factors are associated with pediatric eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 141:214-222.

O'Shea, KM; Aceves, SS; Dellon, ES; Gupta, SK; Spergel, JM; Furuta, GT; Rothenberg, ME. Pathophysiology of Eosinophilic Esophagitis. Gastroenterology. 2018; 154:333-345.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:74-75.