Rothenberg CURED Lab

Publications from the Rothenberg Lab

These journal article publications are the culmination of our research projects, steps forward in our understanding of biological and diseases processes, a sharing of our findings with others, and a basis for further research.

These steps forward would not be possible without the generous support of many foundations and agencies, such as the Campaign Urging Research for Eosinophilic Disease (CURED) and the National Institutes of Health (NIH).

Publications

Selected Publications

Wen, T; Aronow, BJ; Rochman, Y; Rochman, M; Kiran, KC; Dexheimer, PJ; Putnam, P; Mukkada, V; Foote, H; Rehn, K; et al. Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. Journal of Clinical Investigation. 2019; 129:2014-2028.

Travers, J; Rochman, M; Miracle, CE; Habel, JE; Brusilovsky, M; Caldwell, JM; Rymer, JK; Rothenberg, ME. Chromatin regulates IL-33 release and extracellular cytokine activity. Nature Communications. 2018; 9.

Shoda, T; Wen, T; Aceves, SS; Abonia, JP; Atkins, D; Bonis, PA; Caldwell, JM; Capocelli, KE; Carpenter, CL; Collins, MH; et al. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. The Lancet Gastroenterology and Hepatology. 2018; 3:477-488.

Azouz, NP; Ynga-Durand, MA; Caldwell, JM; Jain, A; Rochman, M; Fischesser, DM; Ray, LM; Bedard, MC; Mingler, MK; Forney, C; et al. The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses. Science Translational Medicine. 2018; 10.

Martin, LJ; He, H; Collins, MH; Abonia, JP; Myers, JM B; Eby, M; Johansson, H; Kottyan, LC; Hershey, GK K; Rothenberg, ME. Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci. Journal of Allergy and Clinical Immunology. 2018; 141:1690-1698.

Caldwell, JM; Collins, MH; Kemme, KA; Sherrill, JD; Wen, T; Rochman, M; Stucke, EM; Amin, L; Tai, H; Putnam, PE; et al. Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation. Mucosal Immunology. 2017; 10:1190-1201.

Davis, BP; Stucke, EM; Khorki, ME; Litosh, VA; Rymer, JK; Rochman, M; Travers, J; Kottyan, LC; Rothenberg, ME. Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. JCI insight. 2016; 1.

Kottyan, LC; Davis, BP; Sherrill, JD; Liu, K; Rochman, M; Kaufman, K; Weirauch, MT; Vaughn, S; Lazaro, S; Rupert, AM; et al. Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. Nature Genetics. 2014; 46:895-900.

Wen, T; Stucke, EM; Grotjan, TM; Kemme, KA; Abonia, JP; Putnam, PE; Franciosi, JP; Garza, JM; Kaul, A; King, EC; et al. Molecular diagnosis of eosinophilic esophagitis by gene expression profiling. Gastroenterology. 2013; 145:1289-1299.

2021

Jin, K; Bardes, EE; Mitelpunkt, A; Wang, JY; Bhatnagar, S; Sengupta, S; Krummel, DP; Rothenberg, ME; Aronow, BJ. A Web Portal and Workbench for Biological Dissection of Single Cell COVID-19 Host Responses. 2021.

Rothenberg, ME. An Allergic Basis for Abdominal Pain. New England Journal of Medicine. 2021; 384:2156-2158.

Dellon, ES; Gonsalves, N; Rothenberg, ME; Hirano, I; Chehade, M; Peterson, KA; Falk, GW; Murray, JA; Gehman, LT; Chang, AT; et al. Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab. Clinical Gastroenterology and Hepatology. 2021.

Sabet, C; Klion, AD; Bailey, D; Jensen, E; Chehade, M; Abonia, JP; Rothenberg, ME; Furuta, GT; Muir, AB. Do rural health disparities affect prevalence data in pediatric eosinophilic esophagitis?. Journal of Allergy and Clinical Immunology: In Practice. 2021; 9:2549-2551.

Safroneeva, E; Pan, Z; King, E; Martin, LJ; Collins, MH; Yang, G; Capocelli, KE; Arva, NC; Abonia, JP; Atkins, D; et al. Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms Following Dilation in Adults with Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2021.

Ma, C; Schoepfer, AM; Safroneeva, E; COREOS Collaborators, . Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus. Gastroenterology. 2021.

Dunn, JL M; Caldwell, JM; Ballaban, A; Ben-Baruch Morgenstern, N; Rochman, M; Rothenberg, ME. Bidirectional crosstalk between eosinophils and esophageal epithelial cells regulates inflammatory and remodeling processes. Mucosal Immunology. 2021.

Rochman, M; Xie, YM; Mack, L; Caldwell, JM; Klingler, AM; Osswald, GA; Azouz, NP; Rothenberg, ME. Broad transcriptional response of the human esophageal epithelium to proton pump inhibitors. Journal of Allergy and Clinical Immunology. 2021; 147:1924-1935.

Chiang, AW T; Duong, LD; Shoda, T; Nhu, QM; Ruffner, M; Hara, T; Aaron, B; Joplin, E; Manresa, MC; Abonia, JP; et al. Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:718-722.

Jacobsen, EA; Jackson, DJ; Heffler, E; Mathur, SK; Bredenoord, AJ; Pavord, ID; Akuthota, P; Roufosse, F; Rothenberg, ME. Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies. Annual Review of Immunology. 2021; 39:719-757.

Azouz, NP; Klingler, AM; Callahan, V; Akhrymuk, IV; Elez, K; Raich, L; Henry, BM; Benoit, JL; Benoit, SW; Noé, F; et al. Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. Pathogens and Immunity. 2021; 6:55-74.

Mersha, TB; Afanador, Y; Johansson, E; Proper, SP; Bernstein, JA; Rothenberg, ME; Hershey, GK K. Resolving Clinical Phenotypes into Endotypes in Allergy: Molecular and Omics Approaches. Clinical Reviews in Allergy and Immunology. 2021; 60:200-219.

Dellon, ES; Collins, MH; Rothenberg, ME; Assouline-Dayan, Y; Evans, L; Gupta, S; Schoepfer, A; Straumann, A; Safroneeva, E; Rodriguez, C; et al. Long-term Efficacy and Tolerability of RPC4046 in an Open-Label Extension Trial of Patients With Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2021; 19:473-483.e17.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2021; 147:851-852.

Dellon, ES; Shaheen, O; Koutlas, NT; Chang, AO; Martin, LJ; Rothenberg, ME; Jensen, ET. Early life factors are associated with risk for eosinophilic esophagitis diagnosed in adulthood. Diseases of the Esophagus. 2021; 34.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2021; 147:490-491.

Hempel, T; Raich, L; Olsson, S; Azouz, NP; Klingler, AM; Hoffmann, M; Pöhlmann, S; Rothenberg, ME; Noé, F. Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat. Chemical Science. 2021; 12:983-992.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2021; 147:43-44.

O'Shea, KM; Rochman, M; Shoda, T; Zimmermann, N; Caldwell, J; Rothenberg, ME. Eosinophilic esophagitis with extremely high esophageal eosinophil counts. Journal of Allergy and Clinical Immunology. 2021; 147:409-412.e5.

Kottyan, LC; Trimarchi, MP; Lu, X; Caldwell, JM; Maddox, A; Parameswaran, S; Lape, M; D'Mello, RJ; Bonfield, M; Ballaban, A; et al. Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes. Journal of Allergy and Clinical Immunology. 2021; 147:255-266.

Lyles, JL; Martin, LJ; Shoda, T; Collins, MH; Trimarchi, MP; He, H; Kottyan, LC; Mukkada, VA; Rothenberg, ME. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. Journal of Allergy and Clinical Immunology. 2021; 147:244-254.e6.

Czyzewski, T; Daniel, N; Rochman, M; Caldwell, J; Osswald, G; Collins, M; Rothenberg, M; Savir, Y. Machine learning approach for biopsy-based identification of eosinophilic esophagitis reveals importance of global features. IEEE Open Journal of Engineering in Medicine and Biology. 2021; PP:1-1.

2020

Roufosse, F; Kahn, JE; Rothenberg, ME; Wardlaw, AJ; Klion, AD; Kirby, SY; Gilson, MJ; Bentley, JH; Bradford, ES; Yancey, SW; et al. Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial. Journal of Allergy and Clinical Immunology. 2020; 146:1397-1405.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:1341-1342.

Rothenberg, ME. Transferring allergies in the womb. The Scientific monthly. 2020; 370:907-908.

Hiremath, G; Krischer, JP; Rothenberg, ME; Dellon, ES. Validation of self-reported diagnosis of eosinophilic gastrointestinal disorders patients enrolled in the CEGIR contact registry. Gastroenterologie Clinique et Biologique. 2020.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:993-994.

Dellon, ES; Peterson, KA; Murray, JA; Falk, GW; Gonsalves, N; Chehade, M; Genta, RM; Leung, J; Khoury, P; Klion, AD; et al. Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis. New England Journal of Medicine. 2020; 383:1624-1634.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:774-775.

Ben Baruch-Morgenstern, N; Rochman, M; Rothenberg, ME. Pumping mast cells out of allergic inflammation-are proton pump inhibitors taking center stage?. Journal of Allergy and Clinical Immunology. 2020; 146:783-785.

Jensen, ET; Aceves, SS; Bonis, PA; Bray, K; Book, W; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Gonsalves, N; et al. High Patient Disease Burden in a Cross-sectional, Multicenter Contact Registry Study of Eosinophilic Gastrointestinal Diseases. Journal of Pediatric Gastroenterology and Nutrition. 2020; 71:524-529.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:507-508.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:256-257.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 146:50-51.

Pesek, RD; Reed, CC; Collins, MH; Muir, AB; Fulkerson, PC; Menard-Katcher, C; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; et al. Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. Digestive Diseases and Sciences. 2020; 65:2024-2035.

Lindsley, AW; Schwartz, JT; Rothenberg, ME. Eosinophil responses during COVID-19 infections and coronavirus vaccination. Journal of Allergy and Clinical Immunology. 2020; 146:1-7.

Brusilovsky, M; Rochman, M; Azouz, NP; Mack, LE; Rothenberg, ME. Uncovering the secretes of allergic inflammation. Journal of Clinical Investigation. 2020; 130:3419-3421.

Dunn, JL M; Shoda, T; Caldwell, JM; Wen, T; Aceves, SS; Collins, MH; Dellon, ES; Falk, GW; Leung, J; Martin, LJ; et al. Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort. Journal of Allergy and Clinical Immunology. 2020; 145:1629-1640.e4.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:1549-1550.

Azouz, NP; Klingler, AM; Pathre, P; Besse, JA; Ben Baruch-Morgenstern, N; Ballaban, AY; Osswald, GA; Brusilovsky, M; Habel, JE; Caldwell, JM; et al. Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis. Science Translational Medicine. 2020; 12.

Collins, MH; Martin, LJ; Wen, T; Abonia, JP; Putnam, PE; Mukkada, VA; Rothenberg, ME. Eosinophilic Esophagitis Histology Remission Score: Significant Relations to Measures of Disease Activity and Symptoms. Journal of Pediatric Gastroenterology and Nutrition. 2020; 70:598-603.

Safroneeva, E; Aceves, SS; King, E; Sun, Q; Collins, MH; Yang, G; Capocelli, K; Arva, N; Abonia, JP; Atkins, D; et al. Mo1187 DILATION REDUCES POSITIVE CORRELATION BETWEEN SYMPTOMS AND HISTOLOGIC FINDINGS IN ADULTS WITH EOSINOPHILIC ESOPHAGITIS. Gastroenterology. 2020; 158:s-819.

Peterson, KA; Murray, JA; Falk, GW; Gonsalves, N; Chehade, M; Leung, J; Genta, RM; Rothenberg, ME; Khoury, P; Bledsoe, AC; et al. 228 INTERIM RESULTS OF AN OPEN-LABEL EXTENSION STUDY OF ANTOLIMAB, AN ANTI-SIGLEC-8 ANTIBODY, FOR THE TREATMENT OF PATIENTS WITH EOSINOPHILIC GASTRITIS AND/OR EOSINOPHILIC ENTERITIS. Gastroenterology. 2020; 158:s-43.

Dellon, ES; Peterson, KA; Murray, JA; Falk, GW; Gonsalves, N; Chehade, M; Leung, J; Genta, RM; Rothenberg, ME; Khoury, P; et al. 932 HISTOLOGIC AND SYMPTOMATIC IMPROVEMENT ACROSS MULTIPLE FORMS OF EOSINOPHILIC GASTROINTESTINAL DISEASES IN ENIGMA, A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ANTOLIMAB (AK002). Gastroenterology. 2020; 158:s-186.

Gupta, SK; Pesek, R; Wang, Y; Foss, K; Bonis, PA; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Furuta, G; et al. Su1001 CLINICAL CHARACTERISTICS AND DISEASE FEATURES FROM A MULTICENTER LONGITUDINAL COHORT OF EOSINOPHILIC GASTROINTESTINAL DISORDERS MAY INFORM FUTURE STUDIES. Gastroenterology. 2020; 158:s-493.

Gonsalves, N; Doerfler, B; Zalewski, A; Yang, G; Gregory, DL; Martin, LJ; Shoda, T; Aceves, SS; Thompson, K; Rudman-Spergel, A; et al. 229 RESULTS FROM THE ELEMENT STUDY: PROSPECTIVE STUDY OF ELEMENTAL DIET IN EOSINOPHILIC GASTROENTERITIS NUTRITION TRIAL. Gastroenterology. 2020; 158:s-43.

Hamilton, JD; Lim, WK; Hamon, SC; Rothenberg, ME; Collins, MH; Chehade, M; Harel, S; Wipperman, MF; Hirano, I; Dellon, ES; et al. Mo1228 DUPILUMAB NORMALIZES THE EOSINOPHILIC ESOPHAGITIS DISEASE TRANSCRIPTOME IN ADULT PATIENTS WITH EOSINOPHILIC ESOPHAGITIS. Gastroenterology. 2020; 158:s-835.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:1350-1351.

Oliva, S; Azouz, NP; Stronati, L; Rothenberg, ME. Recent advances in potential targets for eosinophilic esophagitis treatments. Expert Review of Clinical Immunology. 2020; 16:421-428.

Henderson, A; Magier, A; Schwartz, JT; Martin, LJ; Collins, MH; Putnam, PE; Mukkada, VA; Abonia, JP; Rothenberg, ME; Fulkerson, PC. Monitoring Eosinophilic Esophagitis Disease Activity With Blood Eosinophil Progenitor Levels. Journal of Pediatric Gastroenterology and Nutrition. 2020; 70:482-488.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:1134-1135.

Applequist, J; Burroughs, C; Jr, RA; Merkel, PA; Rothenberg, ME; Trapnell, B; Desnick, RJ; Sahin, M; Krischer, JP. A novel approach to conducting clinical trials in the community setting: utilizing patient-driven platforms and social media to drive web-based patient recruitment. BMC Medical Research Methodology. 2020; 20.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:771-772.

Bitton, A; Avlas, S; Reichman, H; Itan, M; Karo-Atar, D; Azouz, NP; Rozenberg, P; Diesendruck, Y; Nahary, L; Rothenberg, ME; et al. A key role for IL-13 signaling via the type 2 IL-4 receptor in experimental atopic dermatitis. Science Immunology. 2020; 5.

Mersha, T; Gautam, Y; Caldwell, J; Rothenberg, M. Genome-wide admixture and association analyses identify novel eosinophilic esophagitis-associated loci in African American ancestry. Journal of Allergy and Clinical Immunology. 2020; 145.

Avlas, S; Itan, M; Dolitzky, A; Varol, C; Rothenberg, M; Munitz, A. Intraesophageal administration of oxazolone to skin-sensitized mice results in experimental eosinophilic esophagitis‏ ‏resembling human disease. Journal of Allergy and Clinical Immunology. 2020; 145.

Munitz, A; Bitton, A; Avlas, S; Reichman, H; Itan, M; Karo-Atar, D; Azouz, N; Rozenberg, P; Nahari, L; Rothenberg, M; et al. A key role for IL-13 signaling via the type 2 IL-4 receptor in atopic dermatitis. Journal of Allergy and Clinical Immunology. 2020; 145.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:474-475.

Hirano, I; Dellon, ES; Hamilton, JD; Collins, MH; Peterson, K; Chehade, M; Schoepfer, AM; Safroneeva, E; Rothenberg, ME; Falk, GW; et al. Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis. Gastroenterology. 2020; 158:111-122.e10.

Vanoni, S; Zeng, C; Marella, S; Uddin, J; Wu, D; Arora, K; Ptaschinski, C; Que, J; Noah, T; Waggoner, L; et al. Identification of anoctamin 1 (ANO1) as a key driver of esophageal epithelial proliferation in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2020; 145:239-254.e2.

Pesek, RD; Rothenberg, ME. Eosinophilic gastrointestinal disease below the belt. Journal of Allergy and Clinical Immunology. 2020; 145:87-89.e1.

Shoda, T; Wen, T; Caldwell, JM; Collins, MH; Besse, JA; Osswald, GA; Abonia, JP; Arva, NC; MDd, DA; Capocelli, KE; et al. Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. Journal of Allergy and Clinical Immunology. 2020; 145:255-269.

Aceves, S; Collins, MH; Rothenberg, ME; Furuta, GT; Gonsalves, N; Abonia, JP; Almonte, S; Andrews, R; Arrington, A; Arva, N; et al. Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Journal of Allergy and Clinical Immunology. 2020; 145:28-37.

Kottyan, LC; Parameswaran, S; Weirauch, MT; Rothenberg, ME; Martin, LJ. The genetic etiology of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2020; 145:9-15.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2020; 145:85-86.

2019

Kurten, RC; Rawson, R; Shoda, T; Duong, LD; Adejumobi, D; Levy, R; Newbury, RO; Rothenberg, ME; Akuthota, P; Wright, BL; et al. Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. Scientific Reports. 2019; 9.

Klion, AD; Rothenberg, ME. Advances in eosinophilic diseases in 2018. Journal of Allergy and Clinical Immunology. 2019; 144:1490-1494.

Rothenberg, ME; Bousquet, J. News beyond our pages. Journal of Allergy and Clinical Immunology. 2019; 144:1511-1512.

Doucet-Ladeveze, R; Holvoet, S; Raymond, F; Foata, F; Hershey, GK K; Sherrill, JD; Rothenberg, ME; Blanchard, C. Transcriptomic Analysis Links Eosinophilic Esophagitis and Atopic Dermatitis. Frontiers in Pediatrics. 2019; 7.

Wen, T; Rothenberg, ME. Cell-by-cell deciphering of T cells in allergic inflammation. Journal of Allergy and Clinical Immunology. 2019; 144:1143-1148.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:1156-1157.

Lyles, J; Rothenberg, M. Role of genetics, environment, and their interactions in the pathogenesis of eosinophilic esophagitis. Current Opinion in Immunology. 2019; 60:46-53.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:924-925.

Muir, AB; Jensen, ET; Wechsler, JB; Menard-Katcher, P; Falk, GW; Aceves, SS; Furuta, GT; Dellon, ES; Rothenberg, ME; Spergel, JM. Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. Journal of Allergy and Clinical Immunology: In Practice. 2019; 7:2434-2436.

Rothenberg, ME; Bousquet, J. News beyond our pages. Journal of Allergy and Clinical Immunology. 2019; 144:643-644.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:395-396.

Ben Baruch-Morgenstern, N; Shoda, T; Rothenberg, ME. Bagels and LOX in patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2019; 144:41-43.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 144:36-37.

Wheeler, JC; Vanoni, S; Zeng, C; Waggoner, L; Yang, Y; Wu, D; Uddin, J; Karns, R; Kottyan, L; Mukkada, V; et al. 17β-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling. Journal of Allergy and Clinical Immunology. 2019; 143:2131-2146.

Pesek, RD; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, C; Falk, GW; Kuhl, J; Martin, EK; Magier, AZ; Ahmed, F; et al. Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium. American Journal of Gastroenterology. 2019; 114:984-994.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:2009-2010.

DiTommaso, LA; Rosenberg, CE; Eby, MD; Tasco, A; Collins, MH; Lyles, JL; Putnam, PE; Mukkada, VA; Rothenberg, ME. Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia. Journal of Allergy and Clinical Immunology. 2019; 143:1928-1930.e3.

Dunn, JL; Shoda, T; Wen, T; Aceves, SS; Abonia, JP; Atkins, D; Bonis, PA; Caldwell, JM; Capocelli, K; Carpenter, CL; et al. 818 – Cytokine Expression Illustrates Heterogeneity of Active Eosinophilic Esophagitis in a Large Multi-Site Cohort. Gastroenterology. 2019; 156:s-173.

Shoda, T; Wen, T; Caldwell, JM; Collins, MH; Abonia, JP; Bonis, PA; Chehade, M; Dellon, ES; Falk, GW; Gonsalves, N; et al. 165 – Development of the Eosinophilic Gastritis Molecular Diagnostic Panel. Gastroenterology. 2019; 156:s-39.

Jensen, ET; Abonia, JP; Aceves, SS; Bonis, PA; Bray, K; Book, WM; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; et al. Mo1133 – High Patient-Reported Disease Burden for Eosinophilic Gastrointestinal Disorders. Gastroenterology. 2019; 156:s-717.

Hirano, I; Collins, MH; King, E; Sun, Q; Abonia, JP; Bonis, PA; Chehade, M; Dellon, ES; Falk, GW; Gonsalves, N; et al. 357 – Prospective Evaluation of a Novel, Endoscopic Activity Assessment System for Eosinophilic Gastritis. Gastroenterology. 2019; 156.

Dellon, ES; Peterson, KA; Genta, RM; Murray, JA; Gonsalves, N; Chehade, M; Rothenberg, ME; Khoury, P; Bledsoe, AC; Singh, B; et al. Mo1127 – Mast Cells in Addition to Eosinophils are Markedly Elevated At Baseline in Patients with Eosinophilic Gastritis And/Or Gastroenteritis. Gastroenterology. 2019; 156:s-714.

Kliewer, K; Aceves, SS; Atkins, D; Bonis, PA; Chehade, M; Collins, MH; Dellon, ES; Fei, L; Gupta, SK; Kagalwalla, AF; et al. 817 – Efficacy of 1-Food and 4-Food Elimination Diets for Pediatric Eosinophilic Esophagitis in a Randomized Multi-Site Study. Gastroenterology. 2019; 156.

Muir, AB; Jensen, ET; Wechsler, JB; Menard-Katcher, P; Aceves, SS; Falk, GW; Furuta, G; Dellon, ES; Rothenberg, ME; Spergel, J. Su1754 – Overestimation of the Prevalence of Eosinophilic Colitis with Reliance on a Single Billing Code. Gastroenterology. 2019; 156:s-605.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:1729-1730.

Kottyan, LC; Maddox, A; Braxton, JR; Stucke, EM; Mukkada, V; Putnam, PE; Abonia, JP; Chehade, M; Wood, RA; Pesek, RD; et al. Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Genes and Immunity. 2019; 20:281-292.

Krishnan, U; Lijuan, C; Andrew, GJ; Rothenberg, ME; Wen, T. Analysis of eosinophilic esophagitis in children with repaired congenital esophageal atresia. Journal of Allergy and Clinical Immunology. 2019; 143:1455-1464.e2.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:1334-1335.

Azouz, NP; Rothenberg, ME. Mechanisms of gastrointestinal allergic disorders. Journal of Clinical Investigation. 2019; 129:1419-1430.

Miller, DE; Forney, C; Rochman, M; Cranert, S; Habel, J; Rymer, J; Lynch, A; Schroeder, C; Lee, J; Sauder, A; et al. Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14. G3: Genes, Genomes, Genetics. 2019; 9:729-736.

Schwartz, JT; Morris, DW; Collins, MH; Rothenberg, ME; Fulkerson, PC. Eosinophil progenitor levels correlate with tissue pathology in pediatric eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2019; 143:1221-1224.e3.

Gupta, SK; Falk, GW; Aceves, SS; Chehade, M; Collins, MH; Dellon, ES; Gonsalves, N; Hirano, I; Mukkuda, VA; Peterson, KA; et al. Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration. Gastroenterology. 2019; 156:838-842.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:921-922.

Hirano, I; Collins, MH; Assouline-Dayan, Y; Evans, L; Gupta, S; Schoepfer, AM; Straumann, A; Safroneeva, E; Grimm, M; Smith, H; et al. RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis. Gastroenterology. 2019; 156:592-603.e10.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:540-541.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2019; 143:76-77.

2018

Ghosh, D; Bernstein, JA; Hershey, GK K; Rothenberg, ME; Mersha, TB. Leveraging Multilayered "Omics " Data for Atopic Dermatitis: A Road Map to Precision Medicine. Frontiers in Immunology. 2018; 9.

Zeng, C; Vanoni, S; Wu, D; Caldwell, JM; Wheeler, JC; Arora, K; Noah, TK; Waggoner, L; Besse, JA; Yamani, AN; et al. Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 142:1843-1855.

Syed, M; Ball, JP; Mathis, KW; Hall, ME; Ryan, MJ; Rothenberg, ME; Cardozo, LL Y; Romero, DG. MicroRNA-21 ablation exacerbates aldosterone-mediated cardiac injury, remodeling, and dysfunction. American Journal of Physiology - Endocrinology and Metabolism. 2018; 315:E1154-E1167.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:1750-1751.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:1439-1440.

Trisno, SL; Philo, KE D; McCracken, KW; Cata, EM; Ruiz-Torres, S; Rankin, SA; Han, L; Nasr, T; Chaturvedi, P; Rothenberg, ME; et al. Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification. Cell Stem Cell. 2018; 23:501-515.e7.

Hiremath, G; Kodroff, E; Strobel, MJ; Scott, M; Book, W; Reidy, C; Kyle, S; Mack, D; Sable, K; Abonia, P; et al. Individuals affected by eosinophilic gastrointestinal disorders have complex unmet needs and frequently experience unique barriers to care. Gastroenterologie Clinique et Biologique. 2018; 42:483-493.

Dellon, ES; Liacouras, CA; Molina-Infante, J; Furuta, GT; Spergel, JM; Zevit, N; Spechler, SJ; Attwood, SE; Straumann, A; Aceves, SS; et al. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. 2018; 155:1022-1033.e10.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:1054-1055.

Rosenberg, CE; Mingler, MK; Caldwell, JM; Collins, MH; Fulkerson, PC; Morris, DW; Mukkada, VA; Putnam, PE; Shoda, T; Wen, T; et al. Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2018; 73:1892-1901.

Chehade, M; Jones, SM; Pesek, RD; Burks, AW; Vickery, BP; Wood, RA; Leung, DY M; Furuta, GT; Fleischer, DM; Henning, AK; et al. Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research. Journal of Allergy and Clinical Immunology: In Practice. 2018; 6:1534-1544.e5.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:785-786.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:396-397.

Peinhaupt, M; Roula, D; Theiler, A; Sedej, M; Schicho, R; Marsche, G; Sturm, EM; Sabroe, I; Rothenberg, ME; Heinemann, A. DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator. Journal of Leukocyte Biology. 2018; 104:159-171.

Khoury, P; Akuthota, P; Ackerman, SJ; Arron, JR; Bochner, BS; Collins, MH; Kahn, J; Fulkerson, PC; Gleich, GJ; Gopal-Srivastava, R; et al. Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of Leukocyte Biology. 2018; 104:69-83.

Spergel, JM; Aceves, SS; Kliewer, K; Gonsalves, N; Chehade, M; Wechsler, JB; Groetch, M; Friedlander, J; Dellon, ES; Book, W; et al. New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting. Journal of Allergy and Clinical Immunology. 2018; 142:48-53.

Aceves, SS; King, E; Collins, MH; Yang, G; Capocelli, KE; Abonia, JP; Atkins, D; Bonis, PA; Carpenter, CL; Dellon, ES; et al. Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites. Journal of Allergy and Clinical Immunology. 2018; 142:130-138.e1.

Rochman, M; Azouz, NP; Rothenberg, ME. Epithelial origin of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 142:10-23.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 142:62-63.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:2017-2018.

Lynch, MK; Barnes, MJ; Dimmitt, RA; Martin, L; Rothenberg, ME; Goodin, BR. Disease-Related Predictors of Health-Related Quality of Life in Youth With Eosinophilic Esophagitis. Journal of Pediatric Psychology. 2018; 43:464-471.

Collins, MH; Hirano, I; Dellon, ES; Peterson, KA; Chehade, M; Schoepfer, AM; Safroneeva, E; Rothenberg, ME; Falk, GW; Assouline-Dayan, Y; et al. Sa1151 - Baseline Characteristics and Correlation Between Dysphagia and Disease Activity in Patients with Eosinophilic Esophagitis in a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial. Gastroenterology. 2018; 154:s-259.

Reed, CC; Pesek, R; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Ahmed, FN; DeMarshall, M; Carpenter, C; et al. Sa1123 - Histologic Characterization of a Multi-Center Retrospective Cohort of Patients with Eosinophilic Gastrointestinal Disorders. Gastroenterology. 2018; 154.

Dellon, ES; Collins, MH; Assouline-Dayan, Y; Evans, L; Gupta, SK; Schoepfer, AM; Straumann, A; Safroneeva, E; Woo, A; Opiteck, G; et al. Sa1114 - Efficacy and Safety of Rpc4046, an Anti-Interleukin-13 Monoclonal Antibody, in Patients with Active Eosinophilic Esophagitis: Analysis of the Steroid-Refractory Subgroup from the Heroes Study. Gastroenterology. 2018; 154:s-244.

Pesek, R; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; DeMarshall, M; et al. Sa1117 - Treatment Patterns for Eosinophilic Gastritis, Enteritis and Colitis Vary Across Sites and Patient Age in a Multi-Center Consortium. Gastroenterology. 2018; 154.

Hirano, I; Collins, MH; Dellon, ES; Rothenberg, ME; Schoepfer, AM; Chehade, M; Chen, Z; Mannent, L; Graham, NM; Pirozzi, G; et al. Sa1112 - Endoscopic Features are Significantly Associated with Histologic Measures of Disease Activity in Patients with Active Eosinophilic Esophagitis: A Post HOC Analysis of a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial. Gastroenterology. 2018; 154.

Hirano, I; Hamilton, JD; Collins, MH; Lin, Z; Dellon, ES; Chen, Z; Peterson, KA; Chehade, M; Schoepfer, AM; Safroneeva, E; et al. Sa1113 - Correlation Between Esophageal Distensibility and Objective Measures of Disease in Patients with Active Eosinophilic Esophagitis: A Post HOC Analysis of a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial. Gastroenterology. 2018; 154:s-244.

Pesek, R; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; DeMarshall, M; et al. Sa1116 - Demographic Features of Eosinophilic Gastritis, Enteritis and Colitis Using 10 Years of Retrospective Data from a Multi-Center Consortium. Gastroenterology. 2018; 154:s-245.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:1580-1581.

Fulkerson, PC; Rothenberg, ME. Eosinophil Development, Disease Involvement, and Therapeutic Suppression. Advances in Immunology. 2018; 138:1-34.

Sherrill, JD; Kiran, KC; Wang, X; Wen, T; Chamberlin, A; Stucke, EM; Collins, MH; Abonia, JP; Peng, Y; Wu, Q; et al. Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis. JCI insight. 2018; 3.

Lu, TX; Rothenberg, ME. MicroRNA. Journal of Allergy and Clinical Immunology. 2018; 141:1202-1207.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:1210-1211.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:874-875.

Takemura, N; Kurashima, Y; Mori, Y; Okada, K; Ogino, T; Osawa, H; Matsuno, H; Aayam, L; Kaneto, S; Park, EJ; et al. Eosinophil depletion suppresses radiation-induced small intestinal fibrosis. Science Translational Medicine. 2018; 10.

Jensen, ET; Kuhl, JT; Martin, LJ; Langefeld, CD; Dellon, ES; Rothenberg, ME. Early-life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 141:632-637.e5.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:520-521.

Jensen, ET; Kuhl, JT; Martin, LJ; Rothenberg, ME; Dellon, ES. Prenatal, intrapartum, and postnatal factors are associated with pediatric eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2018; 141:214-222.

O'Shea, KM; Aceves, SS; Dellon, ES; Gupta, SK; Spergel, JM; Furuta, GT; Rothenberg, ME. Pathophysiology of Eosinophilic Esophagitis. Gastroenterology. 2018; 154:333-345.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2018; 141:74-75.

2017

Cheng, K; Gupta, SK; Kantor, S; Kuhl, JT; Aceves, SS; Bonis, PA; Capocelli, KE; Carpenter, C; Chehade, M; Collins, MH; et al. Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). 2017; 2:141-155.

Travers, J; Rochman, M; Caldwell, JM; Besse, JA; Miracle, CE; Rothenberg, ME. IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis. Scientific Reports. 2017; 7.

Rozenberg, P; Reichman, H; Zab-Bar, I; Itan, M; Pasmanik-Chor, M; Bouffi, C; Qimron, U; Bachelet, I; Fulkerson, PC; Rothenberg, ME; et al. CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production. Scientific Reports. 2017; 7.

Wen, T; Kuhl, J; Putnam, P; Mukkada, V; Farrell, M; Kaul, A; Cole, C; Rothenberg, ME. A flow cytometry-based diagnosis of eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2017; 140:1736-1739.e3.

Rothenberg, ME; Saito, H; Jr, PR S. Advances in mechanisms of allergic disease in 2016. Journal of Allergy and Clinical Immunology. 2017; 140:1622-1631.

Rothenberg, ME; Bousquet, J. NEWS Beyond our Pages. Journal of Allergy and Clinical Immunology. 2017; 140:1543-1544.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 140:1270-1271.

Rochman, M; Travers, J; Abonia, JP; Caldwell, JM; Rothenberg, ME. Synaptopodin is upregulated by IL-13 in eosinophilic esophagitis and regulates esophageal epithelial cell motility and barrier integrity. JCI insight. 2017; 2.

Miguel-Hidalgo, JJ; Hall, KO; Bonner, H; Roller, AM; Syed, M; Park, CJ; Ball, JP; Rothenberg, ME; Stockmeier, CA; Romero, DG. MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2017; 79:503-514.

Caldwell, JM; Paul, M; Rothenberg, ME. Novel immunologic mechanisms in eosinophilic esophagitis. Current Opinion in Immunology. 2017; 48:114-121.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 140:980-981.

Rothenberg, M; Durrani, S. Recent advances in eosinophilic esophagitis. F1000Research. 2017; 6.

Rochman, M; Travers, J; Miracle, CE; Bedard, MC; Wen, T; Azouz, NP; Caldwell, JM; Kiran, KC; Sherrill, JD; Davis, BP; et al. Profound loss of esophageal tissue differentiation in patients with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2017; 140:738-749.e3.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 140:683-684.

Qin, M; Wang, L; Li, F; Yang, M; Song, L; Tian, F; Yukht, A; Shah, PK; Rothenberg, ME; Sharifi, BG. Oxidized LDL activated eosinophil polarize macrophage phenotype from M2 to M1 through activation of CD36 scavenger receptor. Atherosclerosis. 2017; 263:82-91.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 140:379-380.

Wen, T; Rothenberg, ME. Clinical Applications of the Eosinophilic Esophagitis Diagnostic Panel. Frontiers in Medicine. 2017; 4.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 140:55-56.

Litosh, VA; Rochman, M; Rymer, JK; Porollo, A; Kottyan, LC; Rothenberg, ME. Calpain-14 and its association with eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2017; 139:1762-1771.e7.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 139:1784-1785.

Kottyan, LC; Rothenberg, ME. Genetics of eosinophilic esophagitis. Mucosal Immunology. 2017; 10:580-588.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 139:1459-1460.

Goldberg, MR; Elizur, A; Nachshon, L; Appel, MY; Levy, MB; Golobov, K; Goldberg, R; Stein, M; Rothenberg, ME; Katz, Y. Oral immunotherapy-induced gastrointestinal symptoms and peripheral blood eosinophil responses. Journal of Allergy and Clinical Immunology. 2017; 139:1388-1390.e4.

Hiremath, GS; Kodroff, E; Strobel, MJ; Scott, M; Book, W; Reidy, C; Kyle, S; Mack, D; Sable, K; Abonia, P; et al. Tu1073 Analysis of Unmet Needs of Individuals Affected by Eosinophilic Gastrointestinal Disorders: Towards Health Promotion and Effective Care. Gastroenterology. 2017; 152:s851-s852.

Jensen, ET; Shaheen, O; Koutlas, NT; Chang, AO; Martin, LJ; Rothenberg, ME; Baron, JA; Dellon, ES. Tu1100 Early Life Factors are Associated with Risk for Eosinophilic Esophagitis Diagnosed in Adulthood. Gastroenterology. 2017; 152.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 139:1129-1130.

Lyons, JJ; Liu, Y; Ma, CA; Yu, X; O'Connell, MP; Lawrence, MG; Zhang, Y; Karpe, K; Zhao, M; Siegel, AM; et al. ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans. Journal of Experimental Medicine. 2017; 214:669-680.

Collins, MH; Martin, LJ; Alexander, ES; Boyd, JT; Sheridan, R; He, H; Pentiuk, S; Putnam, PE; Abonia, JP; Mukkada, VA; et al. Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring. Diseases of the Esophagus. 2017; 30:1-8.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 139:762-763.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 139:453-454.

Wen, T; Rothenberg, ME. The Regulatory Function of Eosinophils. Myeloid Cells in Health and Disease. 2017.

Goodman, MA; Manesh, DM; Malik, P; Rothenberg, ME. CRISPR/Cas9 in allergic and immunologic diseases. Expert Review of Clinical Immunology. 2017; 13:5-9.

Verma, AH; Bueter, CL; Rothenberg, ME; Deepe, GS. Eosinophils subvert host resistance to an intracellular pathogen by instigating non-protective IL-4 in CCR2-/- mice. Mucosal Immunology. 2017; 10:194-204.

Rothenberg, ME; Bousquet, J. News Beyond Our Pages. Journal of Allergy and Clinical Immunology. 2017; 139:47-48.

Funding Support

Many foundations and agencies, such as the Campaign Urging Research for Eosinophilic Diseases (CURED), generously support our work in the lab to help patients with eosinophilic diseases, including gastrointestinal disorders, asthma and food allergies. Funding Support

CD22 Expression on Gastrointestinal Eosinophils

Reproduction of part of Figure 3, panel B published in The Journal of Immunology (February 1, 2012, vol. 188, p. 1075-1082), showing cell membrane expression of Pan-B cell marker CD22 on gastrointestinal eosinophils of wild type mice by FACS and flow imaging analysis. Copyright 2011. The American Association of Immunologists, Inc. Read More