Ghosh, D; Bernstein, JA; Hershey, GK K; Rothenberg, ME; Mersha, TB.
Leveraging Multilayered "Omics " Data for Atopic Dermatitis: A Road Map to Precision Medicine.
Frontiers in Immunology.
2018;
9.
Zeng, C; Vanoni, S; Wu, D; Caldwell, JM; Wheeler, JC; Arora, K; Noah, TK; Waggoner, L; Besse, JA; Yamani, AN; et al.
Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis.
Journal of Allergy and Clinical Immunology.
2018;
142:1843-1855.
Travers, J; Rochman, M; Miracle, CE; Habel, JE; Brusilovsky, M; Caldwell, JM; Rymer, JK; Rothenberg, ME.
Chromatin regulates IL-33 release and extracellular cytokine activity.
Nature Communications.
2018;
9.
Syed, M; Ball, JP; Mathis, KW; Hall, ME; Ryan, MJ; Rothenberg, ME; Cardozo, LL Y; Romero, DG.
MicroRNA-21 ablation exacerbates aldosterone-mediated cardiac injury, remodeling, and dysfunction.
American Journal of Physiology - Endocrinology and Metabolism.
2018;
315:E1154-E1167.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
142:1750-1751.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
142:1439-1440.
Trisno, SL; Philo, KE D; McCracken, KW; Cata, EM; Ruiz-Torres, S; Rankin, SA; Han, L; Nasr, T; Chaturvedi, P; Rothenberg, ME; et al.
Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification.
Cell Stem Cell.
2018;
23:501-515.e7.
Hiremath, G; Kodroff, E; Strobel, MJ; Scott, M; Book, W; Reidy, C; Kyle, S; Mack, D; Sable, K; Abonia, P; et al.
Individuals affected by eosinophilic gastrointestinal disorders have complex unmet needs and frequently experience unique barriers to care.
Gastroenterologie Clinique et Biologique.
2018;
42:483-493.
Dellon, ES; Liacouras, CA; Molina-Infante, J; Furuta, GT; Spergel, JM; Zevit, N; Spechler, SJ; Attwood, SE; Straumann, A; Aceves, SS; et al.
Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference.
Gastroenterology.
2018;
155:1022-1033.e10.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
142:1054-1055.
Rosenberg, CE; Mingler, MK; Caldwell, JM; Collins, MH; Fulkerson, PC; Morris, DW; Mukkada, VA; Putnam, PE; Shoda, T; Wen, T; et al.
Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis.
Allergy: European Journal of Allergy and Clinical Immunology.
2018;
73:1892-1901.
Chehade, M; Jones, SM; Pesek, RD; Burks, AW; Vickery, BP; Wood, RA; Leung, DY M; Furuta, GT; Fleischer, DM; Henning, AK; et al.
Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research.
Journal of Allergy and Clinical Immunology: In Practice.
2018;
6:1534-1544.e5.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
142:785-786.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
142:396-397.
Peinhaupt, M; Roula, D; Theiler, A; Sedej, M; Schicho, R; Marsche, G; Sturm, EM; Sabroe, I; Rothenberg, ME; Heinemann, A.
DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator.
Journal of Leukocyte Biology.
2018;
104:159-171.
Khoury, P; Akuthota, P; Ackerman, SJ; Arron, JR; Bochner, BS; Collins, MH; Kahn, J; Fulkerson, PC; Gleich, GJ; Gopal-Srivastava, R; et al.
Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).
Journal of Leukocyte Biology.
2018;
104:69-83.
Shoda, T; Wen, T; Aceves, SS; Abonia, JP; Atkins, D; Bonis, PA; Caldwell, JM; Capocelli, KE; Carpenter, CL; Collins, MH; et al.
Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study.
The Lancet Gastroenterology and Hepatology.
2018;
3:477-488.
Spergel, JM; Aceves, SS; Kliewer, K; Gonsalves, N; Chehade, M; Wechsler, JB; Groetch, M; Friedlander, J; Dellon, ES; Book, W; et al.
New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting.
Journal of Allergy and Clinical Immunology.
2018;
142:48-53.
Aceves, SS; King, E; Collins, MH; Yang, G; Capocelli, KE; Abonia, JP; Atkins, D; Bonis, PA; Carpenter, CL; Dellon, ES; et al.
Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites.
Journal of Allergy and Clinical Immunology.
2018;
142:130-138.e1.
Rochman, M; Azouz, NP; Rothenberg, ME.
Epithelial origin of eosinophilic esophagitis.
Journal of Allergy and Clinical Immunology.
2018;
142:10-23.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
142:62-63.
Azouz, NP; Ynga-Durand, MA; Caldwell, JM; Jain, A; Rochman, M; Fischesser, DM; Ray, LM; Bedard, MC; Mingler, MK; Forney, C; et al.
The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses.
Science Translational Medicine.
2018;
10.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
141:2017-2018.
Lynch, MK; Barnes, MJ; Dimmitt, RA; Martin, L; Rothenberg, ME; Goodin, BR.
Disease-Related Predictors of Health-Related Quality of Life in Youth With Eosinophilic Esophagitis.
Journal of Pediatric Psychology.
2018;
43:464-471.
Martin, LJ; He, H; Collins, MH; Abonia, JP; Myers, JM B; Eby, M; Johansson, H; Kottyan, LC; Hershey, GK K; Rothenberg, ME.
Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci.
Journal of Allergy and Clinical Immunology.
2018;
141:1690-1698.
Collins, MH; Hirano, I; Dellon, ES; Peterson, KA; Chehade, M; Schoepfer, AM; Safroneeva, E; Rothenberg, ME; Falk, GW; Assouline-Dayan, Y; et al.
Sa1151 - Baseline Characteristics and Correlation Between Dysphagia and Disease Activity in Patients with Eosinophilic Esophagitis in a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial.
Gastroenterology.
2018;
154:s-259.
Reed, CC; Pesek, R; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Ahmed, FN; DeMarshall, M; Carpenter, C; et al.
Sa1123 - Histologic Characterization of a Multi-Center Retrospective Cohort of Patients with Eosinophilic Gastrointestinal Disorders.
Gastroenterology.
2018;
154.
Dellon, ES; Collins, MH; Assouline-Dayan, Y; Evans, L; Gupta, SK; Schoepfer, AM; Straumann, A; Safroneeva, E; Woo, A; Opiteck, G; et al.
Sa1114 - Efficacy and Safety of Rpc4046, an Anti-Interleukin-13 Monoclonal Antibody, in Patients with Active Eosinophilic Esophagitis: Analysis of the Steroid-Refractory Subgroup from the Heroes Study.
Gastroenterology.
2018;
154:s-244.
Pesek, R; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; DeMarshall, M; et al.
Sa1117 - Treatment Patterns for Eosinophilic Gastritis, Enteritis and Colitis Vary Across Sites and Patient Age in a Multi-Center Consortium.
Gastroenterology.
2018;
154.
Hirano, I; Collins, MH; Dellon, ES; Rothenberg, ME; Schoepfer, AM; Chehade, M; Chen, Z; Mannent, L; Graham, NM; Pirozzi, G; et al.
Sa1112 - Endoscopic Features are Significantly Associated with Histologic Measures of Disease Activity in Patients with Active Eosinophilic Esophagitis: A Post HOC Analysis of a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial.
Gastroenterology.
2018;
154.
Hirano, I; Hamilton, JD; Collins, MH; Lin, Z; Dellon, ES; Chen, Z; Peterson, KA; Chehade, M; Schoepfer, AM; Safroneeva, E; et al.
Sa1113 - Correlation Between Esophageal Distensibility and Objective Measures of Disease in Patients with Active Eosinophilic Esophagitis: A Post HOC Analysis of a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial.
Gastroenterology.
2018;
154:s-244.
Pesek, R; Reed, CC; Muir, AB; Fulkerson, PC; Menard-Katcher, CD; Falk, GW; Kuhl, J; Magier, AZ; Ahmed, FN; DeMarshall, M; et al.
Sa1116 - Demographic Features of Eosinophilic Gastritis, Enteritis and Colitis Using 10 Years of Retrospective Data from a Multi-Center Consortium.
Gastroenterology.
2018;
154:s-245.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
141:1580-1581.
Fulkerson, PC; Rothenberg, ME.
Eosinophil Development, Disease Involvement, and Therapeutic Suppression.
Advances in Immunology.
2018;
138:1-34.
Sherrill, JD; Kiran, KC; Wang, X; Wen, T; Chamberlin, A; Stucke, EM; Collins, MH; Abonia, JP; Peng, Y; Wu, Q; et al.
Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis.
JCI insight.
2018;
3.
Lu, TX; Rothenberg, ME.
MicroRNA.
Journal of Allergy and Clinical Immunology.
2018;
141:1202-1207.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
141:1210-1211.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
141:874-875.
Takemura, N; Kurashima, Y; Mori, Y; Okada, K; Ogino, T; Osawa, H; Matsuno, H; Aayam, L; Kaneto, S; Park, EJ; et al.
Eosinophil depletion suppresses radiation-induced small intestinal fibrosis.
Science Translational Medicine.
2018;
10.
Jensen, ET; Kuhl, JT; Martin, LJ; Langefeld, CD; Dellon, ES; Rothenberg, ME.
Early-life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis.
Journal of Allergy and Clinical Immunology.
2018;
141:632-637.e5.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
141:520-521.
Jensen, ET; Kuhl, JT; Martin, LJ; Rothenberg, ME; Dellon, ES.
Prenatal, intrapartum, and postnatal factors are associated with pediatric eosinophilic esophagitis.
Journal of Allergy and Clinical Immunology.
2018;
141:214-222.
O'Shea, KM; Aceves, SS; Dellon, ES; Gupta, SK; Spergel, JM; Furuta, GT; Rothenberg, ME.
Pathophysiology of Eosinophilic Esophagitis.
Gastroenterology.
2018;
154:333-345.
Rothenberg, ME; Bousquet, J.
News Beyond Our Pages.
Journal of Allergy and Clinical Immunology.
2018;
141:74-75.