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The Stem Cell Program at Cincinnati Children's is focused on these areas of research:
Click image to see a faculty member's interests.
Microenvironment dependent hematopoietic stem cell signaling: physiology and leukemia
Normal hematopoiesis: cell intrinsic and extrinsic mechanisms of hematopoietic stem cell self-renewal
Mechanism of neutrophil extravasation and impact on tissue inflammation
In leukemia, role of inflammatory factors in leukemia initiation and development
Regulation of hematopoiesis with a specific focus in using imaging and mouse genetics to understand the bidirectional communication between hematopoietic stem cells and their niches and how this communication regulates steady-state and regenerative hematopoiesis
Hematopoietic stem cell adaptation to obesity and other organismal stresses
Differential regulation and hematopoietic and leukemic stem cells
Mechanisms of leukemia initiation
If you are interested in learning more about opportunities in the Stem Cell Program, including faculty and postdoctoral positions, email Jose Cancelas, MD, PhD, at jose.cancelas@cchmc.org.