Hematological Malignancy Program
The Hematological Malignancy Program at Cincinnati Children's is focused on these areas of research:
- Molecular and cellular basis of leukemia, myelodysplastic syndromes (MDS) and bone marrow failure (BMF)
- Signal transduction, transcriptional control, epigenetics, genetic drivers, non-coding RNAs and RNA processing in normal and malignant hematopoiesis
- Metabolic and genotoxic perturbations during transformation
- Animal models of myeloid malignancies
- Drug discovery and development and pre-clinical studies
- Pediatric phase I new anti-cancer drug studies
