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In the past fiscal year, the outstanding faculty of the Cincinnati Children’s Research Foundation have collaborated on an impressive body of work.
The following stories summarize our most significant findings of the year, as selected by a committee of senior research leaders.
We hope that sharing these breakthroughs will inspire even more innovation to improve child health in the years ahead.
Single-Cell Approach Reveals Impact of Disease-Causing Gene Mutations Kyle Ferchen, BS, H. Leighton Grimes, PhD, Nathan Salomonis, PhD, and Andre Olsson, PhD
World's First Three-Organoid System Opens Doors for Medical Research Diagnosis Kentaro Iwasawa, MD, Jim Wells, PhD, Aaron Zorn, PhD, and Takanori Takebe, MD, PhD
Dose Escalation Sharply Improves Hydroxyurea Benefit for Children with Sickle Cell Anemia Russell Ware, MD, PhD, Teresa Latham, MA, and Adam Lane, PhD
Clinical Trial Success for HLH Treatment Alexi Grom, MD, and Michael Jordan, MD
Cardiac Stem Cell Therapy Improves Scar Formation Rather Than Prompting Cardiomyocyte Growth Ronald Vagnozzi, PhD, and Jeffery Molkentin, PhD
Our Research Annual Report highlights more than 50 research divisions and institutes, as well as funding, awards and statistics from across the Cincinnati Children's Research Foundation.