The Wen Lab investigates cutting-edge aspects of:
- single-cell RNA sequencing (scRNA-seq) of human tissue residential T cells, and
- thymic lymphopoietin (TSLP)—T helper type 2 (Th2) cell in-tissue differentiation
Our research utilizes genome-wide analysis and innovative techniques that Dr. Wen has developed to provide molecular and cellular insight regarding the pathogenesis of human Th2 disorders using EoE as the model disease.
Investigating the roles of TSLP in Th2 cells differentiation is an ongoing research interest in the Wen Lab. Dr. Wen supervises the Eosinophilic Diagnostic Panel (EDP) that he co-invented, as evidenced by collaborative projects with the Rothenberg Lab.