Liver Development, Disease, Transplant and Regeneration
Our scientists are using cutting edge technologies and experimental model systems such as zebrafish, mouse and human tissue as well as organoids to discover the complex genetic and cellular interactions involved in normal liver development, liver disease pathogenesis and liver transplant rejection. We collaborate with colleagues in the Liver Care Center, Liver Transplant, Autoimmune Liver Disease, and Undiagnosed and Rare Disease Centers to reveal the genetic and developmental basis of liver disease with the goal of improving diagnosis, medical treatment and liver transplant outcomes.
- Akihiro Asai (PFIC, Hepatocyte Differentiation, Bile-Acid Metabolism)
- William Balistreri (Hepatitis, Choleostasis, Alagille, PSC, DILI)
- Julie Bonn (Liver Transplant, Fontan Liver Disease)
- Erica DePasquale (Bioinformatics, Single-cell Sequencing, Software Development)
- Stacey Huppert (Alagille, Bile Duct Development, Regeneration)
- Samuel Kocoshis (intestinal Failure, Cholestasis, Red Cells)
- Alexander Miethke (PSC, AIH, Biliary Atresia, Fibrosis, PFIC)
- Maria Fields (MASLD, Obesity, T cells, Inflammation, Liver)
- Anna Peters (Pediatric Liver Transplant Rejection and Tolerance)
- Takanori Takebe (Liver Development, Stem cell and Organoids, Disease Modeling, Drug Discovery, Regenerative Therapy)
- Amy Taylor (Autoimmune and Cholestatic Liver Disease)
- Yunguan Wang (Bioinformatics, Genomics, Spatial Omics, Autoimmune Liver Disease)
- Stavra Xanthakos (MASH, Obesity, Bariatric, Clinical Trials)
- Chunyue Yin (Cholestasis, Genetics of Rare Liver Diseases, Cholangiocyte Metabolism, PFIC)
