Theresa Alenghat, PhD, Assistant Professor
Molecular mechanisms that mediate intestinal homeostasis and the host-microbiota relationship [Visit the Alenghat Lab ]

Paul Andreassen, PhD, Associate Professor
Fanconi anemia and breast cancer susceptibility proteins in DNA damage responses and genetic stability [Visit the Andreassen Lab ]

Bruce Aronow, PhD, Professor
Integrative bioinformatics and genomics relevant to human health and disease [Visit the Aronow / Jegga Lab ]

Artem Barski, PhD, Assistant Professor
Epigenomics of immunological memory [Visit the Barski Lab ]

Burns C. Blaxall, PhD, FAHA, Professor
Molecular mechanisms and therapeutic discovery for the treatment of heart failure and cardiac fibrosis [Visit the Blaxall Lab ]

Elisa Boscolo, PhD, Assistant Professor
The Boscolo laboratory currently investigates vascular anomalies affecting children, such as venous malformations. The lab is  devising different  murine models of vascular anomalies. The goal of this research is to discover effective molecular therapies for these disfiguring diseases. Research Area: Cardiovascular Biology [Visit the Boscolo Lab]

Jim Bridges, PhD, Research Assistant Professor
Research efforts in the Bridges lab are centered on understanding the molecular regulation of alveolar epithelial cell maturation and function in the developing and adult lung. [Visit the Bridges Lab ]

Samantha Brugmann, PhD, Assistant Professor
The Brugmann Lab studies craniofacial development and disease. [Visit the Brugmann Lab ]

Kenneth Campbell, PhD, Professor
Cellular and molecular control of vertebrate forebrain development [Visit Developmental Biology ]

Jose A. Cancelas Perez, MD, PhD, Associate Professor
Cellular and molecular mechanisms of norm and cancer hematopoietic stem cells [Visit the Cancelas Lab ]

Steven A. Crone, PhD, Assistant Professor
The Crone laboratory studies how neural circuits controlling motor behaviors are affected by disease and injury. Our goal is to develop strategies targeting neural circuits capable of improving motor function and the quality of life of patients suffering from developmental defects, neurodegenerative disease or injury. [Visit the Crone Lab ]

Steve Danzer, PhD, Associate Professor
My laboratory focuses on elucidating the mechanisms by which epilepsy develops, with the ultimate goal of developing novel therapies to prevent or treat the disease. We are currently conducting studies on the roles of the mTOR signaling pathway and adult generated neurons in epilepsy. [Visit the Danzer Lab ]

Biplab DasGupta, PhD, Assistant Professor
Neural stem cells, cancer stem cells, brain cancer and brain development [Visit the Dasgupta Lab ]

Andrew Dauber, MD, Assistant Professor
We are interested in identifying novel genetic etiologies of severe human growth disorders. We use next generation sequencing of patient samples to identify genetic candidates and then explore the underlying functional biology in the lab. [Visit the Dauber-Hwa Lab ]

Tony De Falco, PhD, Assistant Professor
The De Falco lab is interested in uncovering the mechanisms underlying the differentiation of the fetal gonad, focusing on how myeloid cells (such as macrophages) and vasculature promote tissue remodeling during organogenesis. Additionally, we are investigating the roles of myeloid cells in regulating spermatogonial stem cell differentiation in the adult testis. [Visit the De Falco Lab ]

Sudhansu K. Dey, PhD, Professor, Director Division of Reproductive Sciences
Molecular and genetic aspects of embryo implantation in mouse models [Visit the Dey Lab ]

Marie-Dominique Filippi, PhD, Associate Professor
Molecular mechanism of hematopoietic stem cell self-renewal and regeneration; molecular mechanism of neutrophil tissue infiltration and associated inflammation. [Visit the Filippi Lab]

Brian Gebelein, PhD, Associate Professor
Patterning of the nervous and digestive systems during development [Visit the Gebelein Lab ]

Lee Grimes, PhD, Professor
Hematopoiesis, molecular biology, and molecular oncology including mouse modeling of hematopoiesis, myelopoiesis and leukemia. [Visit the Grimes Lab ]

Christina Gross, PhD, Assistant Professor
Identification and analysis of shared molecular mechanisms underlying neurodevelopmental disorders such as Fragile X syndrome, epilepsy and autism, and their use for the development of therapeutic strategies. [Visit the Gross Lab ]

Fumika Hamada, PhD, Assistant Professor
My lab studies temperature sensation and circadian rhythms in Drosophila. [Visit the Hamada Lab ]

John Harley, MD, PhD, Professor
We work to bring the new technologies of genomics to clinical care. We do this for the institution as a service and for our own work in autoimmunity. At the moment we are evaluating the microbiome in blood for systemic lupus erythematosus. [Visit Rheumatology ]

Rashmi Hegde, PhD, Professor
The Hegde laboratory studies molecular mechanisms of angiogenesis in development, cancer and retinal diseases, and is involved in structure- and mechanism-based drug development [Visit the Hegde Lab ]

Gurjit Khurana Hershey, MD, PhD, Professor
Genetics and the pathogenesis of atopic disorders [Visit the Hershey Lab ]

David Hildeman, PhD, Professor
Molecular biology of antigen-specific T cells, including mechanisms involved in cell signaling, apoptosis, and sex-based differences in autoimmunity and the T cell response to viral infections [Visit the Hildeman Lab ]

Stacey S. Huppert, PhD, Associate Professor
Intercellular signaling pathways that regulate the patterning of liver architecture during development and regeneration. [Visit the Huppert Lab ]

Vivian Hwa, PhD, Associate Professor
Genetic and cellular basis of severe pre- and post-natal growth failure in children who often present co-morbitities (immunodeficiencies, insulin insensitivity). [Visit the Dauber-Hwa Lab]

Michael P. Jankowski, PhD, Assistant Professor
Our lab is interested in the molecular mechanisms of sensory neuron plasticity after peripheral injuries and focuses on peripheral mechanisms of ischemic myalgia, and the developmental sensitization of sensory afferents. Using a multidisciplinary experimental approach, our studies will hopefully lead to the development of new treatments for chronic pediatric pain. [Visit the Jankowski Lab ]

Rulang Jiang, PhD, Professor
Understanding the genetic basis and molecular mechanisms of major birth defects [Visit the Jiang Lab ]

Helen N. Jones, PhD, Assistant Professor
My research focuses on placental development and function in pathological pregnancies such as Fetal Growth Restriction and Hypoplastic Left Heart Syndrome. My laboratory is also developing placenta-specific Nanoparticle-mediated gene therapies to improve placental function and pregnancy outcome. [Visit the Jones Lab ]

Tanya V. Kalin, MD, PhD, Associate Professor
Molecular biology of cancer, tumor microenvironment and metastasis. Chemotherapeutic drug development. [Visit the Kalin Lab ]

Vladimir V. Kalinichenko, MD, PhD, Professor
Transcriptional regulation of epithelial and endothelial cell functions during lung embryonic development and lung carcinogenesis. [Visit the Kalinichenko Lab ]

Kenneth Kaufman, PhD, Professor
Utilization of next generation DNA sequencing data to identify variants that cause disease. We are particularly interested in autoimmune diseases such as systemic lupus erythematosus. [Visit CAGE ]

Rafi Kopan, PhD, Professor
The generation of different cell types and specialized organs. [Visit the Kopan Lab ]

Leah Kottyan, PhD, Assistant Professor
The Kottyan lab is focused on identifying the mechanisms that underlie specific genetic associations with immune associated human diseases.  We are especially focused on systemic lupus erythematosus (SLE or lupus) and the chronic food allergic disease eosinophilic esophagitis (EoE). Research Areas:  Genetics, Genomics & Bioinformatics, Immunology [Visit the Kottyan Lab]

Richard Lang, PhD, Professor
Eye development with an emphasis on lens induction and vascular patterning [Visit the Lang Lab ]

Tim Le Cras, PhD, Associate Professor
Chronic lung diseases: Asthma, Bronchopulmonary dysplasia, Pulmonary fibrosis, Pulmonary hypertension [Visit the Le Cras Lab ]

Qing Richard Lu, PhD, Professor
Transcriptional and epigenetic control of glial development and brain tumor initiation [Visit the Lu Lab ]

Satish K. Madala, PhD, Assistant Professor
My laboratory conducts research in pulmonary inflammation and fibrosis. Students working in my laboratory can expect to learn and use a multidisciplinary approach in involving biochemical and physiologic techniques to determine cellular and molecular mechanisms of lung remodeling diseases. [Visit the Madala Lab ]

Doug Millay, PhD, Assistant Professor
We are interested in the mechanisms of cell-cell fusion, using skeletal muscle development and regeneration as a model system. [Visit the Millay Lab ]

Jeffery D. Molkentin, PhD, Professor
Transcriptional control of cardiac development and the molecular signaling pathways involved in cardiac hypertrophy [Visit the Molkentin Lab ]

Louis Muglia, MD, PhD, Professor
Genetic and developmental mechanisms controlling the timing of birth and risk of preterm birth; molecular genetic analysis of the behavioral and neuroendocrine responses to stress. [Visit the Muglia Lab ]

James C. Mulloy, PhD, Professor
Molecular mechanisms involved in leukemia induction and maintenance; mouse modeling of leukemia using primary human blood stem cells [Visit the Mulloy Lab ]

Masato Nakafuku, MD, PhD, Professor
Molecular control of neural stem cells in development and regeneration of mammalian central nervous system [Visit the Nakafuku Lab ]

Takahisa Nakamura, PhD, Assistant Professor
Functional analysis of small RNAs and their binding proteins in integrative organ crosstalk in metabolic diseases. [Visit Endocrinology ]

Satoshi Namekawa, PhD, Assistant Professor
The long-term goal of my research is to understand the mechanisms and evolution of epigenetic events during mammalian reproduction. We study epigenetic regulation of sex chromosomes during meiosis and the regulatory mechanisms in germline stem cells. [Visit the Namekawa Lab ]

A. P. Naren, PhD, Professor
Macromolecular Complexes of CFTR in Cystic Fibrosis and Secretory Diarrhea [Visit Pulmonary Medicine ]

Yuya Ogawa, PhD, Assistant Professor
Molecular mechanisms of long noncoding RNA-mediated epigenetic gene regulation during mammalian development; X-chromosome inactivation using ex vivo differentiation system with mouse ES cells. [Visit Reproductive Sciences ]

Ertugrul Ozbudak, PhD, Associate Professor
The Ozbudak laboratory studies how gene regulatory circuits and signaling pathways controlling pattern formation and cell fate determination in tissues and organs during embryonic development. [Visit the Ozbudak Lab ]

Dao Pan, PhD, Associate Professor  
Combining translational and basic research on virus-mediated, in vivo and ex vivo, gene transfer into stem cells or hepatocytes, as well as their potential application for gene therapy of patients with inherited or acquired diseases. [Visit the Pan Lab ]

Joo-Seop Park, PhD, Assistant Professor
Gene regulatory networks underlying organogenesis and disease, Kidney development. [Visit the Park Lab ]

Anne-Karina Perl, PhD, Associate Professor
We are using mouse models, in vitro organoids and human primary tissue to study alveolarization and alveolar regeneration. We are particularly interested in the plasticity of alveolar fibroblasts, and the fibroblast epithelial interaction that occur in lung development, lung fibrosis and lung regeneration. Research Areas:  Organogenesis, Pulmonary Biology, Stem Cell Biology [Visit the Perl Lab]

Steven Potter, PhD, Professor
Studies of homeobox genes that control mammalian development using gene targeting and transgenic mice [Visit the Potter Lab ]

Nancy Ratner, PhD, Professor
The Ratner lab studies how nerve development is subverted in cancer. We aim to identify targets for therapy in the inherited cancer predisposition syndromes neurofibromatosis type 1 and type 2. [Visit the Ratner Lab ]

Marc Rothenberg, MD, PhD, Professor
Eosinophil biology, chemokine receptor signaling pathways [Visit the Rothenberg Lab ]

Juan Sanchez-Gurmachesh, PhD, Professor

The Sanchez-Gurmaches lab works on understanding the developmental, signaling, and metabolic mechanisms that control adipocyte growth and functions and their contribution to metabolic disease.

Soona Shin, PhD, Assistant Professor
Molecular mechanisms of childhood liver cancer with a focus on hepatic stem/progenitor cells. [Visit the Shin Lab]

Rolf Stottmann, PhD, Assistant Professor
Mouse models of human congenital defects; development of the brain and face. [Visit the Stottmann Lab ]

Saulius Sumanas, PhD, Assistant Professor
Molecular mechanisms of the embryonic vasculature formation [Visit the Sumanas Lab ]

Takanori Takebe, MD, Assistant Professor
Developing a complex organoid (or organ bud) model using human pluripotent stem cells by studying endoderm organogenesis and promoting applications towards modern human development, disease model and therapeutic transplantation. [Visit Gastroenterology, Hepatology & Nutrition]

Bruce Trapnell, MS, MD, Professor
Dr. Trapnell is a physician-scientist with a long-standing focus on the pathogenesis, diagnosis, and therapy of rare lung diseases, the role of GM-CSF in lung homeostasis and defense, and human gene therapy. His laboratory follows a paradigm of translational, pathway-based diagnostic and therapeutic development. Experimental approaches utilize mouse- and non-human primate disease models, molecular and cell biology methodologies, natural history trials, and both investigator- and commercially-sponsored human treatment trials.[Visit Pulmonary Biology]

Charles Vorhees, PhD, Professor
Prenatal origins of neurocognitive and behavioral disorders: How developmental exposure to drugs, environmental agents, chronic stress, and genetic alterations adversely affect brain development and behavior. [Visit the Vorhees Lab ]

Ronald R. Waclaw, MS, PhD, Assistant Professor
Development of forebrain progenitor cells that contribute to the postnatal "neurogenic" niche in the subventricular zone [Visit Experimental Hematology and Cancer Biology ]

Stephen N. Waggoner, PhD, Assistant Professor
We are interested in host and viral factors that control disease pathogenesis by regulating development of long-lived immunological memory, generation of potent immune effector cells, and functional repression of immune function during chronic infection. [Visit the Waggoner Lab ]

Joshua Waxman, PhD, Assistant Professor
My lab is interested in the molecular and genetic mechanisms of organogenesis, with a focus on cardiovascular development. [Visit the Waxman Lab ]

Timothy E. Weaver, PhD, Professor
Lung development; chaperone biology and diseases of protein misfolding; pulmonary fibrosis; asthma; respiratory distress syndrome. [Visit the Weaver Lab ]

Matt Weirauch, PhD, Assistant Professor
My lab uses computational and experimental approaches to study gene regulation, and gene mis-regulation in disease. [Visit the Weirauch Lab]

Jim Wells, PhD, Professor
Endoderm organogenesis and promoting the differentiation of embryonic stem cells into therapeutic endoderm derivatives. [Visit the Wells Lab ]

Susanne Wells, PhD, Professor
Papilloma virus and cervical cancer [Visit the Susanne Wells Lab ]

Jeffrey A. Whitsett, MD, Professor
Organ morphogenesis, gene regulation, cell differentiation, respiratory disease [Visit the Whitsett Lab ]

Kathryn Wikenheiser-Brokamp, MD, PhD, Associate Professor
Our research aims to elucidate the molecular basis of lung development and disease with specific focus on identifying critical biologic functions of the Rb/p16, p53 and Dicer/miRNA pathways in pulmonary progenitor/stem cell growth in the context of organogenesis, repair after injury and disease pathogenesis to identify novel targets with diagnostic and therapeutic utility. [Visit Pathology ]

Michael Williams, PhD, Associate Professor
Interaction of stress-induced hormones and drugs of abuse on adult learning and memory abilities; physiological responses to later stressors; behavioral and physiological consequences of drug reexposure. [Visit the Michael Williams Lab ]

Chunyue Yin, PhD, Assistant Professor
The molecular and cellular mechanisms underlying liver development and disease pathogenesis using the zebrafish model organism. [Visit the Yin Lab ]

Kimberly Yolton, PhD, Associate Professor
Exposures and experiences that may divert infants or children off the typical trajectory of development [Visit the Yolton Lab ]

Yutaka Yoshida, PhD, Assistant Professor
Molecular mechanisms of neural circuit formation in the developing spinal cord, using many techniques including molecular biology, mouse genetics, biochemistry, and electrophysiology to understand them [Visit the Yoshida Lab ]

Katherine Yutzey, PhD, Professor
Morphogenesis of the heart and transcriptional regulatory networks involved in cardiac determination and differentiation; congenital heart disease [Visit the Yutzey Lab ]

Yi Zheng, PhD, Professor
Molecular mechanisms of Rho GTPase signal transduction. Development of novel therapeutic reagents to inhibit Rho pathways related to human pathological conditions [Visit the Zheng Lab ]

Aaron Zorn, PhD, Professor
Molecular mechanisms of endoderm organ development [Visit the Zorn Lab ]